Doctor insights on:
Mosaic Trisomy 22
Trisomy 22: Trisomy is a big word that really only means three copies. Trisomy 22 means three copies of chromosome 22. Trisomy 22 causes many spontaneous pregnancy losses. If a fetus has trisomy 22 it rarely survives into the second or third trimester. If born alive, the newborn usually dies. ...Read more
Ordinary chromosomal traits require a pair of chromosomes to determine the traits. Occasionally, as a mistake in cellular division, there is a tripling of one of the chromosomes. When these occur, they usually cause unpleasant, and sometimes deadly conditions in the inheritor of these traits (e.g. Down's). Many we do not know about as they are ...Read more
Rarely: Most trisomy is due to lack of separation of chromosomes in the maternal gamete (egg). Rarely is trisomy of paternal origin although in downs syndrome, trisomy 21, it occurs in about 5-10%% of cases. Usually, trisomy in sperm results in a selective disadvantage and the sperm rarely compete to fertilize the egg. Trisomy 16 usually results in miscarriage. ...Read more
Can Be: Sometimes it may be the result of abnormal parental chromosomes, sometimes it is spontaneous.Are you rferring to trisomy 21 or down's syndrome? ...Read more
Hx of 4 diagnosed chromosomal pregnancies in a row trisomy 22, 18, 13 & mono 21. I'm 39 yrs old. Is there hope of a normal pregnancy using my own eggs?
Hope yes, but..: Remember, the ancient greeks said that hope was the last evil in pandora's box.. Your history sounds horrible and I am very sorry. There is always a chance of normal pregnancy with your own eggs, however i would recommend genetic counseling and ivf with preimplantation genetic diagnosis in your case (or donor eggs). Take Folic Acid 1-5 mg daily and best of luck! ...Read more
I have trisomy 8 mosaicism without any physical or mental difficulties. I have low platelets and neutrophil levels. Is rai suitable for me hyperthyroi?
Extrachromosome: This means your fetus had 3 copies of the number 20 chromosome, and no evidence of any tissue with the normal 2 copies.Chromosomes carry the instructions that tell the fetus how to form its organs and tissues. When an extra one shows up, it causes confusion in that process and many will miscarry. A few combinations like trisomy 21 can be born but have predictable health problems through life. ...Read moreSee 2 more doctor answers
Chromosomal tripled: Ordinary chromosomal traits require a pair of chromosomes to determine the traits. Occasionally, as a mistake in cellular division, there is a tripling of one of the chromosomes. When these occur, they usually cause unpleasant, and sometimes deadly conditions in the inheritor of these traits (e.g. Down's). Many we do not know about as they are lethal prior to birth. ...Read more
Trisomy 13: Patau syndrome is also called trisomy 13. It occurs when a baby has 3 copies of the number 13 chromosome instead of the usual 2 copies. It causes severe physical problems and most babies with trisomy 13 die before birth or within the first year after birth. It usually happens because of an accident which occurs when the egg is fertilized, and occurs more commonly as mothers get older. ...Read moreSee 1 more doctor answer
See below: It's a rare genetic disorder where duplication of genetic material from chromosome 17 causes various abnormalities. The type and severity of symptoms varies depending on the size and location of the genetic material that is duplicated. Possible symptoms: •impaired intelligence •developmental delay •reduced muscle tone •various facial anomalies •short stature. ...Read moreSee 1 more doctor answer