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Excess of Plasma cel: Plasma cells in our bone marrow make antibodies. Sometimes they become overly active/reactive and produce abnormal proteins called paraproteins. Most such protein production is benign and not uncommon in older folks. Sometimes it is excessive(more than 1gram/day) then we get concerned about a condition called multiple myeloma (paraproteins over 3 grams). ...Read more
Mayo Clinic say: Plasma cells are a type of white blood cell. They are found in your bone marrow. Plasma cells produce some of the antibodies that help your body fight infection. Monoclonal gammopathy of undetermined significance occurs when plasma cells in your bone marrow produce an abnormal protein called monoclonal protein (m protein). ...Read more
MGUS: Is a common precancerous condition affecting people 50 years of age and older. It was first described by mayo clinic researchers in 1978 and is characterized by the presence of an abnormal protein in the blood called a (monoclonal) protein or m protein.Mgus has a small risk (1 percent each year) of progressing to a blood cancer called multiple myeloma or a related condition. ...Read more
Nope: You don't treat an mgus, it is a condition that can ultimately lead to multiple myeloma (risk is about 1% per year) but as of itself does not need therapy (assuming it was correctly diagnosed). You need to have labs checked at least 1 or 2 times a year so you should follow up with your doc indefinitely. ...Read more
What are possible causes of highly elevated ImM levels with low ImG levels with no monoclonal gammopathy present?
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