Doctor insights on:
Molecular Pharmacology Definition
Not sure of question:
If you want to design, research or test drugs, you will have to go thru rigorous study usually ending with a PhD in pharmacology. If you just want some references, I recommend a text "Pharmacotherapy- a physiologic approach bi DiPiro, et al.
Good Luck ...Read more
Pharmacology question - which drugs tend to have generics that may not be equal to the brand name drugs?
Some not all: Those drugs that have a very small difference between effectiveness and toxicity (narrow therapeutic window) are often the target of generic versus brand. Some drugs that fall into this category include warfarin, digoxin, and Phenytoin (extended release capsules). This "window" pertains to oral drugs not usually to injectables. ...Read more
CBT: Seek a cognitive-behavioral therapist who specializes in phobias. One method they use is systematic desensitization which slowly and incrementally brings the person closer and closer to the thing they are afraid of in slow, graduated steps that help make the anxiety more tolerable. ...Read more
Tramadol: Tramadol treats moderate to moderately severe pain. It is an atypical opiod analgesic. It binds to mu opioid receptors & inhibits re-uptake of serotonin/ norepinephrine. Tramadol is narcotic-like pain medication that will be classified as a Schedule IV substance by the DEA in the US effective on 18 August 2014. ...Read more
How severe can become anxiety? Is pharmacology really necessary after several years of psychotherapy all alone?
What's the pharmacology of vistaril (hydroxyzine)? I took it 2 days ago & had slight lip quivering yesterday. How long until it's gone & the quivering is over?
Depends on dose/dura:
Comes in only 2 strengths.
May take up to 1 week but varies with total dose taken. ...Read more
Are there any p450 enzymes that act upon things like acetaminophen and nsaids? I'm really into pharmacology and pharmicokinetics. And take them.
Yes: Cytochrome p450 metabolism accounts for about 5% of the breakdown of acetaminophen, and produces the toxic compound napqi that is responsible for its toxic effect on the liver. Nsaids are hydroxylated by 2c8 & 2c9 in the liver as one of several paths before conversion to the glucuronide & excretion in the urine. ...Read more
Other than topical preparations, 5-FU is a chemotherapeutic drug available by prescription only and often used with other drugs. You should discuss it with your doctor. You may consult this site for info.
http://www. Drugs. Com/sfx/fluorouracil-side-effects. Html ...Read more
SIADH drug treatment:
For information on drugs that treat siadh, please go to this link:
http://www. Webmd. Com/drugs/condition-624-siadh+syndrome. Aspx? Diseaseid=624;diseasename=siadh+syndrome. ...Read more
Doctors who know do: So called sinclair method is effective and I use it not only for problems with alcohol, but also with many other behaviors that needs to be changed, such as gambling, sex addiction, hair pulling and even cravings to food. It works only if not only the patient, but also the family understands the idea and instead of bugging the patient to stop drinking, helps to go along with the program. ...Read more
Common cold: Tips: sore throat – gargle with warm salt water (1/2 tsp salt in 8 oz of water). Get strep test/culture if very sore. Congestion – saline nose drops or netti pot. For anti-inflammatory effect & mobilizing mucus- homemade chicken noodle soup. Hydrate- lots of water/clear broth/ add honey & a small amt. Of lemon juice to chamomile tea. Fever/ pain – Acetaminophen / nsaid’s rest! ...Read more
Hypertension: You can try low salt diet and exercise, along with meditation and yoga but if you have more than a borderline hypertension, you're better off doing those and consulting and doctor for medication. If good control is obtained and you're sticking to the diet, exercise, etc. Can always try to back off the drugs at that point. ...Read more
My 19 days old son gets periodical rash on all over his skin. No other symptoms are noted. Please mention pharmacological and non pharmacological Tx?
Normal?: Without seeing the rash it is impossible to tell; however, there are some "normal" rashes in newborns that go away without treatment. Erythema Toxicum Neonatorum (ETN) and baby acne are two such rashes that need no treatment and will resolve with some patience and time. To get an actual diagnosis, your baby will need to see the pediatrician who can examine the skin and then offer advice. ...Read more
Etomidate (tradenames, mode of action, phamacokinetics, pharmacological action, uses, side effects.), can you tell me this info?
Briefly: Etomidate=Amidate, hypnotic agent used in general anesthesia and brief sedation. It works by altering specific brain receptors (GABA). We use it when we need to have stable or increased heart rate and blood pressure at the beginning of anesthesia (a time when those things can drop quite a bit with other drugs). So, we use for people with certain heart disease, blood loss, trauma, critically ill ...Read more
Does it make pharmacological sense to take 20mg fluoxetine 1 wk per month or better to take it daily for PMDD?
Are there any links between depression and the mechanism (pharmacological action) of isotretinoin in the body? If so, please elaborate on this topic:)
Section 3.3 "biological plausibility" of the linked review paper by bremner et al, 2012:
http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/pmc3276716/
retinoic acid via gene expression has a broad range of effects on the brain, all can lead to mood changes. Although the exact mechanism has not been worked out, bremner et al provides a concise summary of current understanding. ...Read more
How?????: Liver is a complex organ, most of the time protects itself by detoxifying chemicals rarely fails, . Remarkable progress has been made in control of infections, b.P. Stroke, cancer, vas dis meta. Diseases etc by use of medications, prolonging life and virtually every drug could be hepato toxic and unavoidable. Watchful fda withdrawn several (duracet, ruzulin, pemolin etc) may be more to go. ...Read more
What are the possible pharmacological basis of a patient's complain of non response to Sildenafil recommended for management of sexual dysfunction.
Other illness: When a medication for erectile dysfunction doesn't work, assuming the person took the medication as directed, it may be because there are other medical illnesses. Diabetes, high blood pressure, alcohol dependence, or other medications interfering with the sildenafil. Discuss all of this with your treating physician to determine the cause, and you should be able to get this cleared up. ...Read more
Started 28daymarvelon, +have had side effect of sore breasts, only while taking active pills. Quite bad; non-pharmacological way alleviating pain?
Besides reducing salt intake, exercise, and massage, what pharmacological treatments other than diuretics, may be helpful for facial edema?
Causes of facial edema: allergic reactions,
blood transfusion reaction,
conjunctivitis (inflammation of the eye),
drug reactions, including those due to aspirin, penicillin, sulfa, glucocorticoids, and others,
head, nose, or jaw surgery,
injury or trauma to the face (such as a burn),
malnutrition (when severe),
salivary gland disorders,
sinusitis. ...Read more
I read that the pharmacological classification of oral mycostatin (nystatin) is a antifungal antibiotic is this true?
In retinal detachment surgery, how far are we from finding a pharmacological cure for / preventative agent against proliferative vitreoretinopathy?
Decades if ever. Why: Because humans=Hi-Tech, medical system=Low-Tech & issues=complex. Study: https://en. Wikipedia. Org/wiki/Proliferative_vitreoretinopathy & http://goo. Gl/Blh6rW & http://goo. Gl/44sPmg for perspective. The pharma industry (crucial to many easy to use advances) looks for single molecules which interact with our fantastic complexity for more benefit than harm, though later always easier & more common. ...Read more
What is the pharmacological mechanism of action of lithium carbonate when used to treat bipolar disorder?
Unknown: The exact mechanism is not fully understood. It effects sodium transport in nerve cells and may have effects on several neurotransmitters, most notably glutamate and serotonin. It is the most effective agent for mood stability, but may have effects on thyroid and kidneys after many years of continuous use. ...Read more
Do you think pathologies have increased in number/form after the development of modern pharmachology? After all meds create many free radicals.
No: There have always been more pathologies (disorders) than doctors could take care of, and there always will be. We are an imperfect species in an imperfect world. At first, we take care of the pathologies that are very bad and/or the ones that are very easy to treat. Then we go after the other pathologies. Existing diseases sometimes are cured, but new ones do get created, either by man or nature. ...Read more
Supply & demand: Shock occurs when blood flow isn't enough to meet the body's energy needs. Usually, the blood pressure and/or output of the heart is low-the tissues of the body don't get enough oxygen due to inadequate blood flow/perfusion. Sometimes, if the energy requirements of the body are high (hypermetabolic), then seemingly normal supply just isn't enough to meet the demand. ...Read more