Doctor insights on:
Moderately Differentiated Adenocarcinoma Lung
My husband is diagnosed with poorly differentiated adenocarcinoma of the right lung with alk & egfr mutations; stage 3b what is the prognosis and life?
It is extremely unusual to have both mutations. They are mutually exclusive. Patients that do carry one of these mutations are eligible for various medications that target these mutations.
Crizonitib for alk and tarceva (erlotinib) for egfr and new agent recently to the market. These new finding have improved the prognosis. Other factors do enter in. Age, ps, smoking history if any, wt. Loss, etc. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
It is cancer: Adenocarcinoma is a cancer that originates from glandular epithelial cells. This is usually classified as poorly, moderately or well differentiated based on the resemblance of these cells to normal epithelium with the well-differentiated cells being most similar in appearance to the normal cells. The poorer the differentiation, the more aggressive and poorer prognosis. ...Read more
The biopsy results says invasive moderately differentiated adenocarcinoma. Please what does this means and what is the medical cure for this?
My husband was diagnosed with invasive moderately differentiated pulmonary adenocarcinoma. What is the course of treatment?
Your oncologist is t: Your oncologist should guide you in the decisions towards treatment. Cancer treatments are dictated by the stage of disease. So you need to know what stage of lung cancer he has. For early stages, surgery can be the best option but as it goes from stage 1 to 3, chemotherapy and radiotherapy are used in combination. For stage 4 it is mostly chemotherapy which is most useful. ...Read more
What has to be performed in order for the results to show a moderately differentiated adenocarcinoma?
Biopsy: but that result is a simple biopsy, making regular slides and regular coloring of it and looking under the microscope. Identical technology from the 19th century. ...Read more
What does each word/phrase mean?Infiltrating, well differentiated adenocarcinoma; carcinoma focally invades superficial submucosa;no lymphovascular invasion?Is surgery advised for this type of report?
It depends: The answer will depend on several factors, including the location this biopsy came from. ...Read more
64 YO female, biopse: ulcerated colonic mucosa with moderately differentiated adenocarcinoma ... what does it mean and is there a cure?
Yes good out look: If localized has excellent prognosis , get it treated , follow your doctors advise , share your fears with your family and they will give you all the support you need and help you to pass this crisis. good Luck ...Read more
What can be done for poorly differentiated adenocarcinoma arising in the setting of intestinal metaplasia?
CUP?: Cancer 1-2-3 -- 1) diagnosis -- we know cancer , but what kind? May need additional information -- is this a colon polyp, now cancer or what? Pathologist can help and may need special testing. 7% of cancers have know known primary (cup or upc). 2) staging and prognostic factors. 3) treatment. Need all of the pieces of the puzzle before treating. ...Read more
Hello can u tell me what I do histopathology report : section show poorly differentiated mucinous adenocarcinoma with ulceration of mucosal surface?
It is a subtype of cancer that arises from cell of the glands that produces some mucin/mucous.
Where is this located? Colon?
You need to discuss further re- treatment plan with your oncology team. Treatment and everything will depend on what kind of cancer is this? The stage? The molecular pattern/biology of the cancer? Your overall condition? Etc. Good luck. ...Read more
Yes: endometrial cancer which begins in the endometrial mucosa, before invading myometrium or muscle of uterus is virtually 100% cureable. Even if D&C shows tumor cells spreading to blood stream this is not metastasis but cells pushed by curettage into the blood. Even early muscle invasion followed by hysterectomy with node diss. can be cured. ...Read more
What's the option for a patient diagnosed with poorly differentiated adenocarcinomas with mixed inflammation?
Options for Cancer: Need more information, such as where is it located (adenocarcinomas can be in many different organs), is there lymph node involvement, etc Important to remember that there is alway more than one option or approach, including choosing not to treat. Talk it over thoroughly with your oncologist, ask lots of questions, have someone with you to take notes, get 2nd (and 3rd) opinions if necessary. GL ...Read more
My fil,68 yrs,biopsy report stating "well differentiated papillary adenocarcinoma" @ rectosigmoid junction. Dr suggests surgery -R we doing right ?
Any hope for 87 yr old w/ moderately differentiated adenocarcinoma infiltrating lamina propria & muscularis mucosa w/ assoc. Ulceration & necrosis?
Yes: Yes. Which part - colon or rectum? Has it been removed or is this known by ultrasound? Need more info but don't just give up. ...Read more
What prognosis can be expected with a stage 4 appendix cancer diagnosis? It is mucinous adenocarcinoma well differentiated. First diagnosed may 2011 and have had two bowel resections , cytoreductive and hipec followed up with 12 chemo folfox tx
30 year old female, stage iii-b well differentiated adenocarcinoma in sigmoid colon 4 lymph nodes affected was surgically removed. What's better xelox or folfox for chemo? And why?
Trust oncologist: 30 yr old stage iii b needs all that is needed to prevent recurrence , both drugs have oxaplatin , folfox has 5 fu & Folic Acid , xelox has Capecitabine , all comparative studies showed almost equal results, please rely and trust your oncologist advise , as therapies are changing so fast for good , will encourage if you want to take a second opinion good luck ...Read more
Biopsy: "sigmoid colon, well differentiated adenocarcinoma, grade i" does this indicate that the tumor won't probably metastasize? Triphasic CT shows a lesion in the liver (1cm) as well.
Grade 1 is a good:
Sign, but nothing is guaranteed. Need to further understand the liver lesion as well.
Work with the medical team to put together the best treatment plan for the individual patient situation. ...Read more
Lung cancer is curable when found early. There are two broad categories of lung cancer; small cell and non small cell.
Adenocarcinoma is the most common form of non smal cell lung cancer. The prognosis of non small cell lung cancer is impacted more by the stage than it is by the cell type. Adenocarcinoma can be cured. In early stages, only surgery may be required. ...Read more
See doctor: Adenocarcinoma is one of the most common forms of lung cancer and should be taken very seriously. Treatment many times involves surgery, but speak with your doctor about this. Only when knowing the size, stage, location, etc. of the tumor can one give you a reliable recommendation on treatment options. ...Read more
Lung adenoCA at apex: Adenocarcinoma is originated from epithelial tissues which has glandular (with secretory property) and malignant appearance. It is the most common type of lung cancer. When it is located at the 'apex' of the lung, that means at the tip of the upper portion of the lung. ...Read more
Not known at present: Although it can run in families if there is exposure to tobacco smoke or other environmental carcinogens (radon). ...Read more
I dignosed adenocarcinoma lungs stage 4. I am on maintainance chemotharapy of pemetraxed.I want to have a child. Is it safe for me and my child?
Sounds like lung Can: Your biopsy shows cancer, likely arising in your lung.You need to see an oncologist who can run more tests to do the staging. This means trying to determine if it is localized to one spot or could it have spread inside the body. The stage will determine the type of appropriate treatment. ...Read more
What is best treatment if interpretation and comment is grade 2 infiltrating adenocarcinoma of lung ?
Depends on stage: The pathology report is used along with body scans and tests to determine the full stage of the adenocarcinoma. Once the stage and medical history in known then the oncologist, radiologist, and thoracic surgeon can suggest the best surgical, chemotherapy, radiation and/or, immuno therapy, personalized treatment based on the actual oncogenes may also be considered. ...Read more
Dads friend diagnosed with stage 1 non small cell lung adenocarcinoma. Is there a chance of complete cure since its only stage 1?
Yes: stage 1 adeno ca of the lung is generally resectable and therefore has a reasonably good prognosis ...Read more
I have stage IV adenocarcinoma of the lungs. I have had 7 chemo tx. I am more symptomatic at this point. What would you suggest for next treatment?
Can't answer, dear: Seven treatments of the same or different chemos? Has it worked? Are you felling worse because of the chemo or the cancer? More symptomatic like how? Talk openly to your oncologist about your concerns, he/she can answer your questions best. I'm very sort you are not doing well and hope you feel better soon. God bless. ...Read more
Rare: While some very rare genetic syndromes may increase the risk of developing long cancer, the vast majority of lung cancers occur in people without genetic cancer syndromes. While smoking clearly increases the risk of lung cancer, in many patients we can only attribute their development of cancer to bad luck. ...Read more
Survival: Tumor stage and tumor burden meaning what organs are involved and how much disease is there plays a role. Similarly tumor subtype adenocarcinoma, tumor profile egfr mutation or alk mutation can affect survival. Non smokers have better prognosis. For advanced stage, all measures are still considered palliative. Other factors such as general health, infections and thromboembolism can affect survival. ...Read more
The process by which cells become progressively more specialized; a normal process through which cells mature. This process of specialization for the cell comes at the expense of its breadth of potential. Stem cells can, for example, differentiate into secretory ...Read more
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