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Doctor insights on: Mixed Cryoglobulinemia

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Dr. Sheila Smith
23 doctors shared insights

Cryoglobulinemia (Definition)

In cryoglobulinemia blood contains large amounts of cryoglobulins - these abnormal proteins are insoluble at low temperatures. These are present in lot of autoimmune conditions as ...Read more


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Whats mixed connective tissue disease?

Whats mixed connective tissue disease?

Labs can confuse.: The labs are just a fraction of what needed to get you better. Your history and physical exam will determine your treatment. Looking for which labs will delay and confuse. You need to develop a few paragraphs of all your issues and sit down with your doctor to put the pieces together. Began a wellness program and add in magnesium and acupuncture. ...Read more

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Is Mixed Connective Tissue Disease Hereditary?

Is Mixed Connective Tissue Disease Hereditary?

Partly: The exact cause of this disease is still unknown. We believe that there is a genetic or inherited predisposition and a second enviorental trigger for this disease. It is rate to see 2 family members with this disease. Basically this means it is not an inherited disease. The abity to get this disease may be inherited but not the disease itself. ...Read more

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Possible mixed connective tissue disease, doctor says? What is a mixed disease?

Possible mixed connective tissue disease, doctor says?  What is a mixed disease?

MCTD!: Mixed connective tissue disease a much milder disease than the cousins it may share features with: sly, sjogren's, scleroderma. It is characterized by find the "rnp" antibody, in the absence of the sm-antibody. Usually treated with plaquenyl. May have milder sjogren's, raynauds than other diseases, may cause joint pain, but no damage. We treat the sx that dominate and vary between pts with mctd. ...Read more

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What is mixed connective tissue disease?

What is mixed connective tissue disease?

Combination of CTD: Mixed connective tissue disease is an autoimmune conditions with a combination of autoimmune diseases systemic lupus erythematosus, rheumatoid arthritis, scleroderma and polymyositis. One of these conditions is usually more prominent than the others at one time and with time it can progress to the other autoimmune diseases. Thus you may have arthritis, or a rash, or internal medical probelm. ...Read more

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Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

No: It's neither. It's an overgrowth of fibrous tissue that's poorly understood. Sometimes an injection can break it, or surgery's an option. Best wishes. ...Read more

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Is mixed connective tissue disease considered a separate disease entity?

Is mixed connective tissue disease considered a separate disease entity?

Yes: If diagnosed solely on basis of anti-rnp antibodies, no; but if diagnosed clinically on the basis of signs of multiple connective tissue diseases, but which do not allow a specific one to be diagnosed. ...Read more

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Can mixed connective tissue disease be diagnosed with a positive ANA and positive rnp anitibodies?

Can mixed connective tissue disease be diagnosed with a positive ANA and positive rnp anitibodies?

NO.: You must have a compatible clinical picture first and the absence of another diffuse connective tissue disorder which could explain the symptoms and lab findings. A high titer ANA and anti-u1-rnp is a pretty good marker of mctd though. ...Read more

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What is a mixed connective tissue disorder like?

What is a mixed connective tissue disorder like?

Connective Tissue : There are over 200 disorders that impact connective tissue. Some, like cellulitis, are the result of an infection. Injuries can cause connective tissue disorders, such as scars. Others, such as ehlers-danlos syndrome, marfan syndrome, and osteogenesis imperfecta, are genetic. Still others, like scleroderma, have no known cause. Each disorder has its own symptoms and needs different treatment. ...Read more

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What exactly is a mixed connective tissue disorder?

Combination: Combination of signs of a several connective tissue diseases associated with hand swelling and often specific antibodies. ...Read more

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Can a person have mixed connective tissue disease with a positive ANA and low positive rnp levels?

Inprobable: Hight titers of anti rnp antibodies are the trade mark of mctd however it is possible to be in early phase of transformation from a lupus background were other anas are still dominant. The clinical picture would take precedent with overlapping signs such as raynaulds, myositis and other signs of scleroderma. None of these tests are diagnsotic in the absence of clinical illness. ...Read more

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Disease processes associated with a high positive ANA other than autoimmune disorders?

Positive ANA: Conditions that can result in an elevated ANA include autoimmune disorders, certain drugs, uncommon infections, chronic lung or liver disease, kidney failure, ultraviolet light therapy, malignancy, pregnancy, and false positive/lab error. Hope this helps. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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What does mixed atonal/demyelinating poly neuropathy mean and what are diseases associated with it?

What does mixed atonal/demyelinating poly neuropathy mean and what are diseases associated with it?

CIDP-GUILLIAIN BARRE: ATONAL MEANING DYING BACK.IT CAN EFFECT POLY NEUROPATHY DUE TO DEMYELINATION. IT IS CIDP-GUILLIAN BARRE SYNDROME.THERE ARE CASES OF IT IN MANY COUNTRIES. IT CAN DEVELOP AFTER PREVENTIVE SHOT OF INJECTION FOR INFLUENZA. OCCASIONALLY IT CAN BE FATAL, IF IT INVOLVES INTERCOSTAL MUSCLES. ...Read more

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What specialists can diagnose mixed connective tissue disorder?

What specialists can diagnose mixed connective tissue disorder?

Rheumatologist: A rheumatologist is the specialist with the most in depth knowledge of connective tissue disorders. Caution: blood tests such as the rnp antibody do not diagnose mctd nor do they rule it out. The diagnosis must be made from the history and physical examination with blood tests playing a confirmatory role. ...Read more

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Is autoimmune hepatitis connective tissue disorder?

No: Autoimmune hepatitis is an inflammatory condition that effects the liver cells. Antibodies from a patient's own immune system attack the cells of the liver. ...Read more

Dr. James Lin Dr. Lin
4 doctors agreed:
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Does kidney stones go along with having lupus and mixed connective tissue disease?

Dr. James Lin Dr. Lin
4 doctors agreed:
Does kidney stones go along with having lupus and mixed connective tissue disease?

No, ....: To find and establish a connection of a disease with others is essential in medical care with a mind of prevention, but not easy. In the case of kidney stone with le, I have exhausted my recollection of studies, articles, professional meeting and discussion over my 45-yr study and practice in urology, but I have never come across such concern that you raised. So, i would say "no." for now. ...Read more

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What does mixed axonal/demyelinating poly neuropathy mean and what are diseases associated with it?

What does mixed axonal/demyelinating poly neuropathy mean and what are diseases associated with it?

Neuropathy: neuropathies are normally differentiated between axonal and or demyelinating. Axonal is nerve fibers are damaged and demyelinating is covering of the nerves are damaged. All neuropathies may be mixed such as in Guillain-Barré, but most neuropathies are related to hypothyroidism, diabetes, vitamin B12 deficiency and/or alcoholic. A mixed pattern does not provide diagnostic help. Hope that helps ...Read more