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Doctor insights on: Mixed Connective Tissue Disease

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Dr. Laura Herpel
73 doctors shared insights

Mixed Connective Tissue Disease (Overview)

Mixed connective tissue disease is a broad disorder where the body's immune system attacks one's own tissues, affecting the connective tissues of the skin, joins, and muscles.


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Is mixed connective tissue disease considered a separate disease entity?

Is mixed connective tissue disease considered a separate disease entity?

Yes: If diagnosed solely on basis of anti-rnp antibodies, no; but if diagnosed clinically on the basis of signs of multiple connective tissue diseases, but which do not allow a specific one to be diagnosed. ...Read more

Dr. Laura Herpel
73 doctors shared insights

Mixed Connective Tissue Disease (Overview)

Mixed connective tissue disease is a broad disorder where the body's immune system attacks one's own tissues, affecting the connective tissues of the skin, joins, and muscles.


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What are the major presenting symptoms of mixed connective tissue disease?

What are the major presenting symptoms of mixed connective tissue disease?

Joint, skin, interna: Mctd can have a variety of signs and sympotms whichcan change with times. By the name it is a mixture of a variety of connective tissue diseases: systemic lupus erythematosus, scleroderma, polymyositis and rheumatoid arthritis. Depending on which condition is prominent at the time. When you are evaluated your physician will look for causes of the symptoms from these categories. ...Read more

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Managing Raynaud's Disease (Tip)

Managing Raynaud's Disease

Without concomitant vascular occlusive disease raynaud's patients rarely suffer tissue loss (ulcers). ...See more

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Living with Coronary Artery Disease (Checklist)

Take meds as prescribed
Once
Exercise daily as recommended by your doctor or trainer
daily
Limit meat, dairy, and fats as much as possible
Once
Eat whole grains only - not white bread
Once
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What specialists can diagnose mixed connective tissue disease besides rheumatologists?

What specialists can diagnose mixed connective tissue disease besides rheumatologists?

Any physician: It depends on the expertise. As a rheumatologist we may not necessarily have a corner on the market, but depending on what signs and symptoms the patient has they may be diagnosed by other physicians. It is important to be clear what the true diagnosis is since mctd people can have skin, joint, muscle, lung, heart, kidney involvement to name some. It depends on the stage of the mctd. ...Read more

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What are the tests for mixed connective tissue disease?

What are the tests for mixed connective tissue disease?

Not my definition!: Mctd is a non-serious problem for most. The lab definition is usually an rnp antibody without a smith (sm) antibody. ...Read more

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Living with Addison's Disease (Checklist)

Wear a medic alert
Once
Take additional hydrocortisone/prednisone for fever or injury
Once
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Can a person have mixed connective tissue disease with a positive ANA and low positive rnp levels?

Can a person have mixed connective tissue disease with a positive ANA and low positive rnp levels?

Inprobable: Hight titers of anti rnp antibodies are the trade mark of mctd however it is possible to be in early phase of transformation from a lupus background were other anas are still dominant. The clinical picture would take precedent with overlapping signs such as raynaulds, myositis and other signs of scleroderma. None of these tests are diagnsotic in the absence of clinical illness. ...Read more

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Could undifferentiated connective tissue disease (poss sjogrens +\or lupus) cause increased feeling of being winded when it is humid outside?

Could undifferentiated connective tissue disease (poss sjogrens +\or lupus) cause increased feeling of being winded when it is humid outside?

Difficult question: And one that probably can not be answered on this sit specific to you. Some kinds of connective tissue diseases can cause constriction and make you feel short of breath, others not. It is vert variable. The ones you mentioned probably not ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


Connective Tissue (Definition)

There are many types of connective tissue, but in general it is a mass of fibers and thick "goopy" fluids secreted by specialized cells. The body often uses connective tissue to help ...Read more