Doctor insights on:
Replication error: Most changes in dna come from errors in the duplication of the dna. But changes can occur in the structure from radiation and some chemicals especially those used in chemotherapy. Most mutations are harmless, some are tracked down by your normal reparative mechanism but a few can cause trouble including cancer. ...Read more
Tumor: Monoclonal proliferation of lymphoid cells is usually an indication of tumor of the lymphoid tissue. ...Read more
DNA breakdown: Carcinogens can cause cells to rapidly divide in response to the continual attack on their survival. With this high cell turnover coves oxidative/free radical damage (stealing of electrons) and in many case errors in dna sequencing resulted in a mutated dna stand. The body sees this imperfect dna strand as a foreign invader and eliminates it through the immune system. ...Read more
hepatitis b surface antigen reactive and hepatitis b surface antibody nonreactive and core antibody total reactive and HBV DNA detected sir plz reply?
You carry hep B: I am assuming you feel well and this was a surprise finding. There are millions of people like yourself. You will require lifelong health care for it unless / until a means of eradicating it is found. You pose no danger to a partner who is immunized. ...Read more
Flu virus genes: The hemaglutinin and neuraminidase genes are in influenza viruses. They code for proteins that are found on the surface of the flu virus. The viruses are named according to which type of hemaglutinin and neuraminidase proteins are on their surfaces (for example: h1n1 or h7n9). ...Read more
Hbv DNA viral load result: 451.35 iu/ml (1895.67 copies/ml) HBsAG 4.441 and antihbs 0.10. What does this mean? Thank you!
Hepatitis B carrier: You are a hepatitis b carrier - with high levels of hepatitis b surface antigen (hbsag) as well as hbv dna positive. You should see a hepatologist, a liver md for treatment. In this era, there are medications that can suppress hbv dna replication, i.e. Decrease the generation of new viral particles, decreasing injury to the liver and long term complications, such as cirrhosis and liver cancer. ...Read more
Several: Rod monochromatism is most common form of achromatopsia, inherited as autosomal recessive condition; it can be can be caused by more than one gene mutation. So far, mutations or variants of any of 4 genes, cnga3, cngb3, gnat2 and recently pde6c, have been linked to each causing rod monochromatism. These 4 genes appear to account for about 79% of cases of rod monochromatism. See comment below—>. ...Read more
Mitochondria: It sounds like you have been reading about mitochondria, the powerhouse organelle of cells. These organelles use methods to create the cellular currency of energy, Adenosine triphosphate. You probably read that a portion of the ATP synthase complex is embedded in the mitochondrial membrane. Read about it here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278611/ You can consult me if you have Q's ...Read more
Blood flow cytmtry shows dual positive cd4cd30 cells absolute count of 2354. IGG slightly elevated with elevated light chains, T cell Beta clone noted?
Asking what?: If your are requesting a diagnosis online, this is not the appropriate venue. Though the flow cytometry results are not totally normal, your results should be reviewed with the physician who ordered it. This format does not give us the ability to determine if your clinical presentation and lab results are consistent with a specific diagnosis. ...Read more
There are: literally millions of genes that control cell growth not only in pancreatic tissue but throughout the entire body. Why do you ask? ...Read more
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?
Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more
Can autoantibodies against glutamine synthetase and/or glutamate dehydrogenase cause glutamate metabolism disorders?
Still searching: Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. I am unble to find references in my search so far as to autoantibodies to these but see comment. ...Read more
Gene Mutation: This is a mutation in one of the genes that help to process iron absorption. The mutation, if present in 2 copies, can cause too much iron to be absorbed. The excess iron then deposits in other organs and can cause disease - cirrhosis, diabetes, impotence. Having only one mutation may not lead to disease. You should discuss this with your doctor to see if you are at risk of developing disease. ...Read more
Six : Chromosome 6. Why?Get a more detailed answer ›
?: Your question doesn't make any sense. Re-write. ...Read more
Auto-Immune Disorder: I think what you are asking is "elevation of anti-bodies to single strand dna". This means that you body is producing antibodies to specifically target proteins found throughout your body. This is process scene in some common rheumatologic disorders. I would suggest that since you are on Plaquenil (hydroxychloroquine) you physician is already aware of this or at least had the correct suspicion. ...Read more
DNA replication: I would go to wikipedia for this. Cannot think of only 3 steps. There are many more. But if you are taking a class I would look it up in the class text book. ...Read more
Not routinely: But family history and your own risk factors are certainly a way that we individualized care ...Read more
It's complicated...: Dna tests don't compare every gene-pair in one person with those in another person. Instead, there are many types of tests. The tests look at only some sections of people's dna. One can ask the person doing the test which kind of test it is and how likely it is for various matches to occur. Lots of information is at: http://en.Wikipedia.Org/wiki/dna_profiling. ...Read more
Not a chance: At any age all pregnancies have about 4% risk of an unexpected outcome.(Premi, cleft palate, infection,DS,etc) As you pass 40 you begin to add higher risk of DS,as lifelong exposures to toxins affects egg quality.You can get non-invasive (mother's blood) information on a pregnancy as early as 8-10 wks with NIPP.This test commonly done for paternity can also detect DS very early. ...Read moreSee 2 more doctor answers
How safe is it to get a DNA on a baby before its born? And how far along do you need to be? How is it done?
Fetal DNA -: hello ! Firstly, fetal DNA comes from fetal cord sample, done after 16 wks AND before 21 weeks under u/sound. Its risky, significant risk of miscarriage, but if you are looking for significant disease AND are prepared to abort the pregnancy if you find it, then its invaluable. I would NOT advise it if you are not prepared to have an abortion if the fetus proved +ve for the disease you are seek.THX ...Read moreSee 1 more doctor answer
The double strand break in DNA used in Crispr tecnique, is this alteration then passed on to the offspring and future generations..?!
Do all or most blacks get high unassigned levels on 23andme dna ancestry test at the 90% confidence level? I did. Is this common for blacks?
Uncertain: Your best bet is to ask the site what type of genetic material they have. This is how they develop the profile. Your suggestion sounds like it is valid but it is best to ask the source. ...Read more