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Doctor insights on: Mirtazapine Amitriptyline Terms Pain

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Is there a difference between mirtazapine and amitriptyline in terms of effectiveness for pain and sleep?

Is there a difference between mirtazapine and amitriptyline in terms of effectiveness for pain and sleep?

No direct answer: These are 2 different drugs. Again, there is "no better than" or "as good as". Treatment of any disorder should be individualized. I would think that Remeron (mirtazapine) is more often prescribed for sleep disorders where as Amitriptyline is more often prescribed for pain when talking about these 2 conditions specifically. ...Read more

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Mirtazapine (Definition)

Mirtazepine (remeron) is a noradrenergic/specific serotonergic antidepressant [nassa]. It is used for major depressive d/o, various anxiety disorders, chronic pain, and others. In some, it can help ssri-induced sexual dysfunction & "poop out." it can be sedating and also increase appetite -- good for some ...Read more


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Dr gave me amitriptyline 50 mg 1 a day & gave me remeron (mirtazapine) 15mg 1day, im allergic to vistaril does remeron (mirtazapine) have that in it. And which 1 is better to use?

Dr gave me amitriptyline 50 mg 1 a day & gave me remeron (mirtazapine) 15mg 1day, im allergic to vistaril does remeron (mirtazapine) have that in it. And which 1 is better to use?

Different drugs: Benadryl, (diphenhydramine) Remeron &amitriptyline can all have the side effect of sedation & each is sometimes prescribed for use as as sleep aid rather than their primary clinical benefit for allergy related symptoms ( Benadryl) & antidepressant (Remeron & Amitriptyline ). But they are differ in how they are constructed chemically or in the way they work . You & your doctor can decide which medivine may be best. ...Read more

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Would smoking a small amount of weed be safe ( for nerve pain ) be ok with other meds I'm taking. Amitriptyline, mirtazapine, venlafaxine ?

Would smoking a small amount of weed be safe ( for nerve pain ) be ok with other meds I'm taking. Amitriptyline, mirtazapine, venlafaxine ?

Most likely.: While federal regulations prohibit me from recommending the use of schedule I medications such as cannabis I can tell you that there is overwhelmingly scant evidence that its consumption with the drugs that you listed would be risky. That said IF you were to consume it any option other than burning it to ingest it would be preferable: i.e. consider an edible, atomized or nebulized form. ...Read more

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Besides remeron, (mirtazapine) what other med is good for sedation and anxiety? Trazodone gives me terrible nightmares & elavil is evil to get used to.

Besides remeron, (mirtazapine) what other med is good for sedation and anxiety? Trazodone gives me terrible nightmares & elavil is evil to get used to.

Buspar (buspirone) is another: Buspar (buspirone) is a non-addictive anti-anxiety medication. Studies have also shown that approximately 70% of individuals taking anti-anxiety medications can learn to manage anxiety without medication with a course of focused cognitive-behavioral treatments by a psychologist. ...Read more

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My Dr put me on 10mg elavil a tricylic antidepressants.I am Lexapro (escitalopram) 20mg and remeron 30.mg. I suffer from G A D.Are these o k together. Thanks?

My Dr put me on 10mg elavil a tricylic antidepressants.I am Lexapro (escitalopram) 20mg and remeron 30.mg. I suffer from G A D.Are these o k together. Thanks?

Not recommended...: The Mirtazapine (Remeron) is fine. Elavil (amitriptyline) oral and Lexapro or escitalopram oral both increase affecting serotonin levels in the blood. Too much serotonin is a potentially life-threatening situation. Severe signs and symptoms include high blood pressure and increased heart rate that lead to shock. ...Read more

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I needed a second opinion. Is it safe to taper off remeron (mirtazapine) 15mg to 7.5mg while increasing a new antidepressant elavil 12.5mg to 25mg at same time?

Yes, it's safe: It's possible to safely "cross-taper" medications like this -- meaning to lower and stop one while gradually raising the other. Remeron (mirtazapine) and Elavil will be fine in this way, and hopefully the Elavil will be helpful by itself. Be well, . ...Read more

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Does elavil or tofranil help with sleep along with depression thinking of changing my remeron (mirtazapine) because still depressed and massive weight gain?

Elavil? Remeron (mirtazapine)?: Elavil (amitriptyline) and tofranil (imipramine) are both sedating antidepressants. These can also contribute to weight gain, however. It is essential to speak with your prescribing doc so you can discuss your current sxs and side effects and determine the best plan for you going forward. ...Read more

Dr. Robert Kent
362 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Dr. Heidi Fowler
303 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more