Doctor insights on:
Minimal White Matter Disease
Maybe of no signif.: White matter lesions may be caused from a host of circumstances, such as migraine, prior head or neck trauma, hardening of the arteries, inflammation like multiple sclerosis, prior small strokes, effect of some medications such as methotrexate, and is not specific. The location of your concern maybe actually a chronic, lifelong issue. Consult your doctor. ...Read more
White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more
Signal alteration involving the deep and Periventricular white matter is nonspecific but may represent minimal chronic microangiopathic change. ?
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Explain: Minimal punctate FLAIR/T2 hyperintensities are present in the subcortical & deep white matter of the cerebral hemispheres.(Otherwise normal)?
Here goes: I am unaware of why you required an MRI of brain, but the described lesions could be present due to migraine, prior head trauma, smoking, prior infections, even MS, but the description is not the common pattern. Does this help, or do you need more involved answers via Concierge visit? ...Read moreSee 1 more doctor answer
Mri says scattered white matter, also says no lessions or mass effect detected, isn't scattered white matter lesions?
Yes, but...: Nonspecific abnormality (lesion). From your submission, there are no masses, clots, tumors, increased pressure in the brain, etc.-all reassuring. Talk to your doc. ...Read more
Could a finding of multiple small nonspecific subcortical and deep white matter foci of T2 prolongation have any correlation with neuroborreliosis?
Possibly: Yes possibly but that's. not how it's diagnosed. You need clinical evidence ideally with lab confirmation ...Read more
Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more
What does mulitple(atlest 10)tiny t2/flair hyperintense foci in cerebral white matter, predominantly subcortical and deep white matter implies?
See your doctor: Hyperintense white matter signals may mean nothing clinically or could be related to a host of diagnoses, including multiple sclerosis, autoimmune, etc. It has to be correlated to an exam and other testing to make any sense of it, a lot of times it is an incidental finding and means very little clinically. Your doctor will help you understand what this report means to you clinically. ...Read moreSee 1 more doctor answer
Age 66; right hearing loss; MRI; dx: mild chronic deep white matter ischemic changes in the periventricular and subcortical white matter. Please expla?
Mild atrophy with fairly prominentperiventricular and subcortical nonspecific white matter changes. Chronic. What does this mean?
See below: These findings are not uncommon in older persons. They are nonspecific but are more frequently related to chronic small vessel ischemic disease from diabetes or hypertension. The more severe the findings, the more likely they may be related to future development of vascular dementia. If the findings are in a young person, they could be from mutlple sclerosis or other causes & need further eval. ...Read more
Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. Is this serious?
NONSPECIFIC : Although the films were read as suggesting ischemia, location might also suggest prior head trauma, congenital lesions of no consequence, genetic or hereditary issues, even underlying inflammatory condition. This is only "serious", if clinically you are having stroke symptoms or you possess uncontrolled blood pressure or elevation of blood lipids. Likely quite non-diagnostic. ...Read moreSee 1 more doctor answer
Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. What does this mean?
Subcortical ischemia: This translates to changes in the smaller blood vessels that lead to loss of blood flow to the area and then scarring. Somewhat like a small silent stroke and frequently seen in people with migraines. The opinions about this have swayed from very worried, to common and mundane and more recently back to looking to stop the damage (help the blood flow, oxygen and glucose status optimize). ...Read more
My CT report states that there white matter decreased attenuation which is most evident in the parietal white matter. What does this mean?
WM disease: This could be a million things depending on the extent and location. Likely this will require further eval with mr and/or labs to narrow diagnosis. ...Read more
Mild periventricular and subcortical abnormal T2 and FLAIR signal is
nonspecific, but likely representative of chronic microvascular disease ?
Need clarification.: Tiny white matter spots like these can be due to small vessel vascular insufficiency, as mentioned, as well as conditions like multiple sclerosis and Lyme disease. Or they can have no specific cause at all. But in a young person like yourself, a good examination and testing would be in order. ...Read more
Mom is 79 brain CT scan: moderate cerebral volume loss, mild widening of the cortical sulci, mild white matter microvasc. Ischemic disease serious?
Depends: Most likely these are aging changes that have occurred with time. ...Read more
A few scattered punctate foci of increased T2/flair signal of the supratentorial white matter which is nonspecific meaning?
See below: It means you may have tiny lesions in white matter where nerve fibers extend away from nerve cells. The increased signals may indicate areas of injury due to ischemia (lack of oxygen) or other causes. They are too small and few in number to be significant. If you are worried, discuss your concerns with your Dr. You can change your diet, exercise regularly, manage stress and quit smoking if you do. ...Read more
Why did you get it?: If the radiologist knew your age and still read the report in that way I think that is a little bit unusual. But, it kind of depends on the reason you had the MRI done in the first place. Typically, that type of a read would be more common for someone who had long-standing hypertension, diabetes, high cholesterol, smoker for many years and so forth. Do you have a copy of the report or the films ...Read more
81 year old mother, CT periventricular deep white matter changes and moderate small vessel iscjaemic disease. serious?
Not enough info: Not sure what you mean by "white and grey brain matter disorder". Grey matter is basically where brain cell bodies (neurons) are, and white matter is mainly the cables (axons) connecting neurons. Sounds like you had an MRI and need to talk with your doctor about what it shows - "white and grey brain matter disorder" is too vague and doesn't tell me anything useful. ...Read moreSee 1 more doctor answer
Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?
Chronic ischemia: What you are seeing on the mr are common aging changes seen on mr. As for a "cure" being available, not at the moment and likely years before any solution. ...Read more
Highly nonspecific scattered nonenhancing white matter lesions (3mm) the bilateral cerebral hemispheres. Possible ms?I have no other symptoms of ms
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