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Doctor insights on: Minimal Change Disease

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Does kidney disease specifically minimal change disease have any connection with allergies?

Does kidney disease specifically minimal change disease have any connection with allergies?

A possible trigger: The cause of minimal change disease is not fully known but it is believed to be an immune disorder in which t cells release a cytokine that damages the epithelial foot processes of the glomeruli. This leads to a leakage of Albumin by the kidney. Certain events such as a viral infection, an allergic reaction, a bee sting, or an immunization may trigger an attack of mcd. ...Read more

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Dr. Donald Batisky
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Nephrotic Syndrome (Definition)

A condition caused by dysfunction of the kidney in which large amount of protein leak into the urine. Typically three components of the syndrome are 1) protein greater than 3.5 grams per day, 2) low serum albumin, and ...Read more


Dr. John Landi Dr. Landi
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Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Primary tx: Steroids are still primary treatment for minimal change disease; however, treatment is usually limited, as remission is often achieved in a matter of months, with a slow taper off over the following two years or so. If yours can't be tapered off, there are alternatives such as Cyclophosphamide that can be used as steroid-sparing agents, but these require discussion with your nephrologist. ...Read more

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What is a treatment for nephrotic syndrome?

What is a treatment for nephrotic syndrome?

Proper medication: Minimal change (or nil) disease. Correctly diagnosed by biopsy but frequently diagnosed by the symptoms of proteinuria, edema and intact renal function with a bland urine sediment. This responds to steroid therapy most of the time. The presence of blood in the urine, or failure to respond to steroids indicates need for biopsy of kidney with therapy based on those results. Case needs nephrologist. ...Read more

Dr. Joshua Batt Dr. Batt
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Is nephrotic syndrome a genetic disorder and hereditary ? As we need to know this from as our doctor isn't sure many thanks

Is nephrotic syndrome a genetic disorder and hereditary ? As we need to know this from as our doctor isn't sure many thanks

Nephrotic syndrome: Nephrotic syndrome is mainly the loss of protein through the kidneys, sometimes with hypertension, edema, even diabetes. So you see the conditions that can lead to nephrotic syndrome can have genetic predisposition. The nephrotic syndrome is a result of such conditions. ...Read more

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Minimal change disease prognosis?

Minimal change disease prognosis?

Good: With ace inhibitors and steroids it can usually be kept in remission. Compliance with the physicians care plan is essential. It is a good idea to have a nephrologist helping you with this. ...Read more

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Dr. Felix Toro Dr. Toro
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Can you tell me if i could get the lap band surgery with minimal change disease?

Can you tell me if i could get the lap band surgery with minimal change disease?

Here are some...: This Q has been longstanding with no answering. Despite not an expert in bariatrics, based on my lifelong digestion of medical knowledge coupled with common sense, I could not see any interaction between both through uneventful lap band surgery since minimal change disease denotes the usually uneventful kidney changes from various reasons. More? Ask your doctor straight, not circuitous timely. ...Read more

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How dangerous is minimal change disease when steroid resistant? He is 4 yrs old....

How dangerous is minimal change disease when steroid resistant?  He is 4 yrs old....

Poor control ; ...: There is no uniform approach for the individuals with steroid-resistant nephrotic syndrome. Clinical trials utilizing cyclosporin, tacrolimus, or Mycophenolate Mofetil (mmf) with corticosteroid show variable success rate of inducing remission. Therefore, poor control of proteinurua and edema and higher rate of drug toxicity is common. ...Read more

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Eliminate low-fat, high-carb foods from your diet
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Monitor your weight and review your diet daily.
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Is there any new and better treatment for minimal change disease? Im 25yrs on steroids. Was diagnoised wit mcd in 2007. Thank u in advance sir.

Primary tx: Steroids are still primary treatment for minimal change disease; however, treatment is usually limited, as remission is often achieved in a matter of months, with a slow taper off over the following two years or so. If yours can't be tapered off, there are alternatives such as Cyclophosphamide that can be used as steroid-sparing agents, but these require discussion with your nephrologist. ...Read more

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Had nephrotic syndrome 12 yrs ago..minimal change disease. Should I always be on bp drug to protect kidneys? I've been on Losartan and my new dr disc

Had nephrotic syndrome 12 yrs ago..minimal change disease.  Should I always be on bp drug to protect kidneys? I've been on Losartan and my new dr disc

See answer: Minimal Change Disease is one of the more common and treatable kidney diseases. >90% of patients respond to oral steroids, with most having a complete remission. However, >50% of the adults who go into remission will relapse at some point. A nephrologist is the best MD to follow you and determine what medications are best for you based on your BP, edema, renal function, urine protein amount, etc. ...Read more

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Does kidney disease specifically minimal change disease have any connection with allergies?

A possible trigger: The cause of minimal change disease is not fully known but it is believed to be an immune disorder in which t cells release a cytokine that damages the epithelial foot processes of the glomeruli. This leads to a leakage of Albumin by the kidney. Certain events such as a viral infection, an allergic reaction, a bee sting, or an immunization may trigger an attack of mcd. ...Read more

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I have minimal change disease. I want to start using wild yam 2000mg daily as a contraception option. Will this herb damage kidneys more?

I have minimal change disease. I want to start using wild yam 2000mg daily as a contraception option. Will this herb damage kidneys more?

Wild Yam: I do not know of any studies that show that wild yam helps with contraception but it may cause scarring of the kidneys based on a study in 2008 "food and chemical toxicology" journal. Taking unregulated herbs can be a very risk proposition as no one is 100% sure what potential side effects you may have. ...Read more

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Living with Irritable Bowel Syndrome (Checklist)

Try to notice and avoid precipitating factors
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Can secondary infections (sinusitis) cause minimal change disease to flare up...spilling protein.

Can secondary infections (sinusitis)  cause minimal change disease to flare up...spilling protein.

Not really: get a repeat urine analysisi, culture and kidney function studies. You may need a 24 hour urine analysisi and/or a reanl ultrasound if symtoms persisit. ...Read more