Doctor insights on:
Microcytic Macrocytic Anemia
Can macrocytic anemia be due to colon cancer? Mcv 103 and hemoglobin 9.8 for old male. I know only microcytic anemia aan be due to colon cancer?
Yes it depends: You are right that anemia from blood loss like from colon cancer is typically microcytic with a low MCV but the MCV in your case is not high enough to suspect a typical macrocytic anemia like one due to B12 deficiency. Yet we can have a mixed picture. At the moment we are only guessing all this till you have the right investigating/testing done. So i would check your B12 level and bone marrow exam. ...Read more
My dad has macrocytic anemia. His liver and kidney tests are normal. Mch, b12, WBC normal. Could it be due to zyprexa (olanzapine)? Is it riskier than microcytic?
More info: Macrocytic anemia can have many causes and more information is needed. Alcohol intake is a common cause especially when it is accompanied by ingestion of nsaids, the combination causing gastritis and bleeding. There are also hereditary hemoglobin abnormalities that can be detected with additional testing. He should continue to pursue an answer with the help of his primary care provider. ...Read more
Both are ways of....: Describing features of blood cells. Anemia means your red cell mass is 2 standard deviations below the lower norm for age and sex. Macrocytic means the rbcs are bigger than expected (normal red cell size falls within a normal range) and size gives us clues as to the cause of the anemia. Leukopenia means your total WBC count is below normal. A differential is really needed to interpret leukopenia. ...Read more
What is considered abnormal retic count for a 70 yrs man with macrocytic anemia? His Hb is 9. His retic count .85% and retic shape is normal.
Depends.: Retic count should be 1% with a normal Hgb. For a 70 y/o male, that would be about 13. As Hgb goes down young red cells (retics) should go up to correct the deficit. In this case about 2.5 - 3% at least. 0.85% shows poor RBC production. With macrocytosis (large RBCs) consider B12, folate (folic acid) deficiency, certain drugs, liver disease, low thyroid, myelodysplastic syndrome & other bone marrow disease ...Read more
Iron: Most common cause of hypochromic microcytic anemia is iron deficiency in the us. This is particularly true in females. Please discuss with your doctor about getting iron studies and possibly treatment if necessary. There are hemoglobinopathies which can also cause this, but less commonly. ...Read more
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