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Doctor insights on: Microcytic Macrocytic Anemia

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Can macrocytic anemia be due to colon cancer? Mcv 103 and hemoglobin 9.8 for old male. I know only microcytic anemia aan be due to colon cancer?

Can macrocytic anemia be due to colon cancer? Mcv 103 and hemoglobin 9.8 for old male. I know only microcytic anemia aan be due to colon cancer?

Yes it depends: You are right that anemia from blood loss like from colon cancer is typically microcytic with a low MCV but the MCV in your case is not high enough to suspect a typical macrocytic anemia like one due to B12 deficiency. Yet we can have a mixed picture. At the moment we are only guessing all this till you have the right investigating/testing done. So i would check your B12 level and bone marrow exam. ...Read more

Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


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My dad has macrocytic anemia. His liver and kidney tests are normal. Mch, b12, WBC normal. Could it be due to zyprexa (olanzapine)? Is it riskier than microcytic?

My dad has macrocytic anemia. His liver and kidney tests are normal. Mch, b12, WBC normal. Could it be due to zyprexa (olanzapine)? Is it riskier than microcytic?

More info: Macrocytic anemia can have many causes and more information is needed. Alcohol intake is a common cause especially when it is accompanied by ingestion of nsaids, the combination causing gastritis and bleeding. There are also hereditary hemoglobin abnormalities that can be detected with additional testing. He should continue to pursue an answer with the help of his primary care provider. ...Read more

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What are macrocytic anemia and mild absolute leukocytopenia?

What are macrocytic anemia and mild absolute leukocytopenia?

Both are ways of....: Describing features of blood cells. Anemia means your red cell mass is 2 standard deviations below the lower norm for age and sex. Macrocytic means the rbcs are bigger than expected (normal red cell size falls within a normal range) and size gives us clues as to the cause of the anemia. Leukopenia means your total WBC count is below normal. A differential is really needed to interpret leukopenia. ...Read more

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What is considered abnormal retic count for a 70 yrs man with macrocytic anemia? His Hb is 9. His retic count .85% and retic shape is normal.

What is considered abnormal retic count for a 70 yrs man with macrocytic anemia? His Hb is 9. His retic count .85% and retic shape is normal.

Depends.: Retic count should be 1% with a normal Hgb. For a 70 y/o male, that would be about 13. As Hgb goes down young red cells (retics) should go up to correct the deficit. In this case about 2.5 - 3% at least. 0.85% shows poor RBC production. With macrocytosis (large RBCs) consider B12, folate (folic acid) deficiency, certain drugs, liver disease, low thyroid, myelodysplastic syndrome & other bone marrow disease ...Read more

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What is microcytic anemia?

What is microcytic anemia?

SMALLER THAN: Normal red cells (''micro" cytic). This is more times than not associated with iron deficiency. ...Read more

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What are the causes of macrocytic hypochromic anemia?

See below: Macrocytic anemia has several causes. Most common causes are vitamins B12 and folate (folic acid) deficiency, liver disease, alcohol excess. There are other less common causes. ...Read more

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What is microcytic anemia and how is it caused?

Several causes: Microcytic anemia means that the red blood cell count is low, and that the red blood cells are small. This is most common in iron deficiency anemia and in thalassemia (a hereditary form of anemia). It may also be seen in less common forms of anemia. ...Read more

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What is hypochromic microcytic anemia?

What is hypochromic microcytic anemia?

Smaller & paller RBC: Anemia where the RBC look smaller in size and paller- due to decrease hemoglobin content in the rbc. Can be found in iron deficiency anemia, also in Alpha or beta thalassemia minor for instance. ...Read more

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I have hypochromic and microcytic anemia?

I have hypochromic and microcytic anemia?

Iron: Most common cause of hypochromic microcytic anemia is iron deficiency in the us. This is particularly true in females. Please discuss with your doctor about getting iron studies and possibly treatment if necessary. There are hemoglobinopathies which can also cause this, but less commonly. ...Read more