Doctor insights on:
Microangiopathic Disease Of The Brain
I had an MRI done of my brain. I was told it showed that I have mild microvascular disease of the brain. What is that and should I be concerned?
MRI brain results Impression- there is cerebral atrophy with subcortical WMC, consistent wit microangiopathic disease, demyelination, or giliosis?
Covering the bases: That signal that is seen in patients who age is seen very frequently. Most of the time it is what has become known as microangiopathic disease or small vessel disease. Demyelination and gliosis come with a more notable history. Gliosis or scarring and demyelination also produces symptoms that MRI is useful for. Depends on why you had the MRI in the first place. The first entity more common than 2 ...Read more
At different times over the past 2 years on both my brain and heart MRI there has been noted "chronic microvascular disease" changes. What is this?
Tiny artery disease: Micro vascular disease is inside matrix changes with decrease blood flow in tiny arteries effecting brain, heart and kidneys. Also known arteriosclerosis and different from large blood vessel disease[atherosclerosis]with no plaques. Causes are blood pressure, diabetes, cholesterol, uric acid, arthritis, poly cystic ovary. Effects;mini stroke, angina, heart attack and kidney failure. Treat the disease. ...Read more
I had an MRI done an it says mild patchy white matter hyperintensity of the pons is stable likely representing microangiopathic disease mean what doe?
What does "microangiopathic changes in brain scan" mean? Particularly in conjunction with hypertension (on scan)?
If a person has microangiopathic ischemic changes and involutional changes in his brain, could this cause frequent headaches?
No: At your age it would be more surprising if you DIDN'T have such changes. This is extremely common, and doesn't cause headaches. Someone your age who has the new onset of frequent headaches should see their doctor. There are a couple of diagnoses that should be ruled out. ...Read more
I am 54, never smoked, no diabetes with dizziness and resting leg pain. MRI brain showed microangiopathic ischemic change and gliosis. What's this?
Ischemic change: It means cerebral small vessel disease with scarring. High blood pressure and high cholest can contribute to lack of blood supply through small blood vessels leading to lack of sufficient oxygen. Please return to your physician for further workup and treatment or consult a physician on this site. You may be a candidate for aspirin therapy. Could there be a clot causing your leg pain? ...Read more
Signal alteration involving the deep and Periventricular white matter is nonspecific but may represent minimal chronic microangiopathic change. ?
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MRI shows microangiopathic changes of the white matter in both hemispheres. Taking Lamictal and have follow up next week. Should I be upset bc I am!
UNCLEAR QUESTION: Not understanding what you are asking so will comment on what you mentioned. At age 37, unless you possess a vasculitis or have uncontrolled hypertension or smoking, the "microangiopathic" interpretation is totally misleading. You don't say why you take Lamictal, so not sure why you might or might not be upset. Help us to help you. Tell us what you need us to help with. ...Read more
MRI Noted "microangiopathic ischemia with significant white matter changes advanced for patient age (30-35)." What further consultation, examination, and/or testing is needed to determine significance where no risk factors are present (no diabetes, hyper
You should see: a neurologist to minimize further worsening of your condition. ...Read more
Vascular/hematologic: Depends on the source of the microangiopathy. If it is age/atherosclerosis there are progression risk reduction strategies such as blood pressure, lipid control. If you have a microangiopathic hemolysis, that requires a specialist and is an urgent matter that requires immediate evaluation and management. ...Read more
Brain: Gliotic changes are the formation of scar tissue which in this case would be due to small bleeds within the brain ...Read more
It is difficult to explain it this limited space. Refer to the following website for simplistic explanation:
http://www.Heart.Org/heartorg/conditions/heartattack/symptomsdiagnosisofheartattack/coronary-microvascular-disease-mvd_ucm_450320_article.Jsp. ...Read more
What is coronary microvascular disease? What are the symptoms of coronary microvascular disease, and is it true that it is more prominent between women?
Small vessels :
In the heart there are larger epicardial vessels that we bypass and stent , and smaller vessel dz that are too small to mechanically intervene. They both can cause pain but small vessel dz is treated with medications and risk factor modification.
And yes its more commonly diagnosedin women. ...Read more
Small vessel: The big coronary vessels divide and subdivide to form micro vessels which supply the muscles of the heart. Diseases like diabetes can cause atherosclerosis of those tiny vessels where our catheters and wires don't go and we can't balloon or stent it. Usually if you have micro vascular disease we just treat with medications which can help in dilating them. ...Read more
No: Micrvascular disease is a disease process internally. ...Read more
Mild periventricular and subcortical abnormal T2 and FLAIR signal is
nonspecific, but likely representative of chronic microvascular disease ?
Need clarification.: Tiny white matter spots like these can be due to small vessel vascular insufficiency, as mentioned, as well as conditions like multiple sclerosis and Lyme disease. Or they can have no specific cause at all. But in a young person like yourself, a good examination and testing would be in order. ...Read more
What is the difference between coronary vasomotor dysfunction and coronary microvascular disease?
Apples vs oranges:
Coronary Vasomotor dysfxn has to do with autoreg of blood flow to the heart. This involves sympath / parasympathetic innervation of the heart from the brain stem.
Coronary Microvascular dz specifically involves the meta-arterioles in the myocardium that regulate blood flow to a defined local area of the heart. Meta arterioles react to metabolic by-products opening or closing blood flow in that zo ...Read more
See below: The goal of therapy is to reduce myocardial oxygen consumption: reduce heart rate, contractility and wall stress. Betablockers, calcium channel blockers, nitrates and Ranolazine are all used. Aspirin and statins are used to prevent clotting and progression of disease. Anemia should be corrected if present. No smoking. Prognosis depends on on the extent of disease and overall health of the heart. ...Read more
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