Doctor insights on:
Metolazone And Furosemide
If I took an overdosage of furosemide (2x40mg)/ metolazone (1x2.5mg) taken at 8am and 2pm combos, would I be ok the next day? Or still affected?
Furosemide is a potent diuretic which increases dramatically urine output in most patients. It is most frequently used in patients who are fluid overloaded such as in congestive heart failure. Potassium, sodium and magnesium can be lost in excess with the use of Furosemide and must be closely monitored. It is much stronger than other diuretics used for ...Read more
If I had an overdosage of furosemide (2x40mg)/metolazone (1x2.5mg) taken at 8am and 2pm for edema, would I be ok the next day? What electrolytes lost?
Can I take metolazone (5mg) in the morning and hydrochlorothiazide (25mg) in the evening together with furosemide (60mg) for stubborn edema?
No: They are drugs of the same class and there's no benefit in taking both. You list nephrotic syndrome. You will likely need a higher dose of lasix (furosemide). I would start by trying 60 mg twice day (with supervision! As it is dangerous to do this on your own!). Alternatively, change lasix (furosemide) to torsemide which is more potent. ...Read more
Diuretic combo: Yes, both can be taken at the same time. Lasix (furosemide) is a loop diuretic and can be used in combination with Metolazone to deliver a greater diuresis than Lasix (furosemide) gives by its self. You should have your doctor test the patient for other causes of leg edema, such as varicose veins or pulmonary artery hypertension to make sure the edema is being treated appropriately, good luck. ...Read more
Bun creatinine high taking lasix 60 3 days week zaroxolyn (metolazone) 5 mg had chf in march, have afib on heart meds too. Help?
Labs: The increase in your creatinine can be dye to many reason. HF itself can cause abnormal kidney function. Excessive use of Lasix (furosemide) also can make things worse. Suggest you see a kidney doc soon and seek input. Testing is needed including a urine test and a detailed history and exam. Best of luck ...Read more
Water pill: Furosemide is a potent diuretic which increases dramatically urine output in most patients. It is most frequently used in patients who are fluid overloaded such as in congestive heart failure. Potassium, sodium and magnesium can be lost in excess with the use of Furosemide and must be closely monitored. It is much stronger than other diuretics used for high blood pressure control. ...Read more
"Could" cause Overdose w/LASIX (furosemide) can cause dehydration, hypotension, electrolyte imbalance, hypokalemia and hypochloremic alkalosis.
The acute toxicity of LASIX (furosemide) has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. ...Read more
Usually: Lasix (furosemide) is not know to cause birth defects. However, it can cause low potassium levels and, sometimes, rapid loss of fluid through urination. If it is needed to control swelling, it needs to be monitored closely by a nephrologist. Blood tests to confirm the kidney status and potassium level need to be done frequently during the pregnancy. Avoid becoming dehydrated. ...Read more
Furosemide: There are lots of possibilities why a doctor might change a dosage strength. You provide no way to tell. Why don't you ask your doctor? ...Read more
Maybe: Furosemide may decrease breast milk volume by causing dehydration in the mother, which could decrease infant growth. It is excreted into human milk and may inhibit lactation. There are no reports of adverse effects in nursing infants. The manufacturer recommends that caution be used when administering Furosemide to nursing women. ...Read more
Ask provider: Furosemide is often a critical part of keeping a heart with CHF in balance. Without it, there may be swelling, and usually with it, more shortness of breath. Not all CHF patients need a diuretic however, and excessive use may lead to dehydration or even worsening renal function. This is a question best asked of the provider that follows the patient regularly. ...Read more
Possible obstruction: I do not know findings of renal scan. Some people develop pain with diuresis from lasix (furosemide) because of sudden distension of collecting system. This may mean there is obstruction to collecting system or ueter and the sudden increased volume not handled well. Sometimes this occurs in obstructed kidneys following beer ingestion, another diuretic. Pain a lot of times when supine at night. ...Read more
Lasix allergy: Allergic to it.Get a more detailed answer ›
Maybe: What is your kidney function? The response of the kidney to lasix (furosemide) is complex and depends on getting lassie into your blood, then it is bound to albumin and delivered by a complex mechanism to the site where it works. Many factors affect the response of the kidney. You medications reflect you have PPH, and sounds like right side HF. You may not respond because your kidney is sensing pre-renal. ...Read more
Several things: You may need to restrict your salt and fluid intake. You may need a higher dose of Lasix (furosemide) or change to another loop diuretic. You may need additional diuretics which are complementary to the lasix (furosemide). Sometimes lying down and resting after taking the Lasix (furosemide) helps mobilize the fluid. Please talk to your doctor about it. ...Read more
Depends: Depends on 1) what's causing the leg swelling - could be a heart problem, a kidney problem, a liver problem, or just sluggish leg veins, 2) if he's eating salt which makes the body retain water and interferes with the lasix, (furosemide) and 3) what's the dose of Lasix (furosemide) - the effective dose is 20 mg daily for some and 400 for others. Why not go along on the next doctor visit, so you can get more answers. ...Read more
Sometimes helps: One of the first drugs generally tried is acetazolamide (Diamox) which may reduce the production of cerebrospinal fluid. Also, it has been shown to improve symptoms in 47 to 67 percent of patients. If acetazolamide alone isn't effective sometimes it's combined with furosemide (Lasix), a potent diuretic that decreases fluid retention by increasing urine output. ...Read more
High Ceiling Diureti: Increasing the dose above the threshold will ellicit a dose-dependant increase in diuresis until they reach maximum effectiveness. This is called the ceiling effect. So, if you go above the ceiling dose, no extra effect will be achieved. Compared to other diuretics Furosemide has high ceiling effect. ...Read more
I would start by: Drinking more waterGet a more detailed answer ›
Edema: It is necessary to know the reason your husband's feet are swollen as well as the state of his heart and kidneys and venous system. The problem could be not enough dose of Lasix (furosemide) but there are many other possibilities. Should discuss with husband's doctor to get the full explanation of what's going on. ...Read more
Not really: Hyperbaric oxygen treatment actually puts stress on the heart by making it pump against higher pressure. By doing so, it can put patients with weak heart muscle into heart failure which will then require Lasix (furosemide) to treat it. This could happen during the treatment or immediately after. In my practice, we are very careful when treating patients with an EF less than 35% (a sign of a weak pump). ...Read more