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Doctor insights on: Methylphenidate Vs Amphetamine Adhd

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Which is safer methylphenidate or amphetamine for ADHD ?

Which is safer methylphenidate or amphetamine for ADHD ?

Adderall vs Ritalin (methylphenidate): Some patients do not tolerate one but tolerates well the other without any uncomfortable side effect. Both are safe if used and followed up properly. If in adult, insure no cardiac problem before starting stimulants. ...Read more

Amphetamine (Definition)

A psychostimulant, controlled drug schedule ii, with abuse potential. It acts to enhance Dopamine and norepinephrine in the body, including the brain. It can decrease appetite- was used as a diet pill, treat narcolepsy and adhd, pathological fatigue, sea sickness. Derived from ephedra plant ...Read more


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If I'm tolerant to amphetamines like adderall in adhd treatment would the tolerance cross over to ritalin (methylphenidate) if I switched?

If I'm tolerant to amphetamines like adderall in adhd treatment would the tolerance cross over to ritalin (methylphenidate) if I switched?

Tolerance likely: You say you're "tolerant" to amphetamines rather than they're not helping your ADHD. That is a word most ADD/ADHD patients don't use in my experience. If you mean you're not feeling a buzz or more pleasant mood effect from amphetamines, I would recommend avoiding any medication including Ritalin (methylphenidate) which is potentially addictive. There are other meds for ADHD which are safer for you. ...Read more

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If ritalin didn't help my ADHD & strattera (atomoxetine) didn't also, which other options do I have if there are no amphetamine medications here ?

If ritalin didn't help my ADHD & strattera (atomoxetine) didn't also, which other options do I have if there are no amphetamine medications here ?

Non-drug solutions: Medications are not the only solution to adhd, and many people with mild adhd (myself included) manage with making lists and developing habits of checking those lists at specific intervals, and of not trying to carry around more than 2 thoughts at any given time. If vyvanse, (lisdexamfetamine) which is an amphetamine precursor, is not available, am not sure what drug options you have, if doses have been optimal. ...Read more

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Will ritalin (methylphenidate) show up as an amphetamine on a drug screen?

Will ritalin (methylphenidate) show up as an amphetamine on a drug screen?

Not likely: Usually methylphenidate will only show up if specifically tested for. Since it isn't an amphetamine, it will not trigger that test. Some rehabs look for it as do some employers. If you take any controlled substance under a doctor's prescription, you should have documentation from that doctor so that you won't be penalized. ...Read more

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Are Ritalin (methylphenidate) and Adipex amphetamines?

Both stimulants: Ritalin (methylphenidate) is a safe medication when taken as prescribed. Adipex ha been shown to be a dangerous medication and there are warnings about the potential dangers. It is taken as a weight loss treatment. ...Read more

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Does amphetamine appear as a false positive of ritalin (methylphenidate)?

In a drug screen, : methylphenidate, the generic name for Ritalin & other preparations, does not show up as amphetamine. Amphetamine products like Adderall & Vyvanse (lisdexamfetamine) can show up in a drug test, but are not a problem if the persons being tested present their prescription bottles at the time of testing. ...Read more

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What are the differences in levels of pns stimulation among commonly prescribed amphetamines, specifically dextroamphetamine and methylphenidate?

Depends on dose: The two medication families are comparable. It depends on the dose prescribed and factors of absorption and metabolism. ...Read more

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Hi, does anyone know what the dose of ritalin is compared to the dose of adderall (dextroamphetamine and racemic amphetamine)? I.E. Is 20mg of methylphenidate equal to roughly 20mg of adderall (dextroamphetamine and racemic amphetamine)?

Hi, does anyone know what the dose of ritalin is compared to the dose of adderall (dextroamphetamine and racemic amphetamine)? I.E. Is 20mg of methylphenidate equal to roughly 20mg of adderall (dextroamphetamine and racemic amphetamine)?

No: As i understand it, the rule of thumb for dosing-equivalence between Ritalin (methylphenidate) and amphetamine (d-amphetamine) is 1mg dexamphetamine = 2mg Ritalin (methylphenidate) (approximately). So the amphetamine is roughly twice as potent. However, Adderall is not pure amphetamine--it's a mix of amphetamine compounds--various versions of d-amphetamine bonded to other chemicals. They do this so mostly that the dose enters the bl. ...Read more

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Why does ritalin (methylphenidate) show up as an amphetamine ?

Stimulant x-reaction: Methylphenidate (ritalin) may cross-react with the amphetamine screen in a urine or saliva drug test. Urine samples may be sent for confirmation testing, which should separate Ritalin (methylphenidate) from the other stimulants. But it will cost more to get confirmation than the drug screen costs. ...Read more

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What's the difference between methylphenidate and regular amphetamine?

Chemical structure: The main difference is simply in chemical structure. The actions are similar. The effects of amphetamines last, in adults, on average 4 hours and those of methylphenidate last about 2.5 hours. ...Read more

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Is it true that methylphenidate is a pro-amphetamine and that, when you take it, it transforms, inside of your body, into amphetamine?

Not really: While they have similar actions methylphenidate is a dopamine reuptake inhibitor while true amphetamine is a dopamine reuptake inhibitor and a dopamine releasing agent. ...Read more

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Is it okay to use beta blockers (propranolol) with amphetamines and methylphenidate to counteract uncomfortable stimulant effects?

Is it okay to use beta blockers (propranolol) with amphetamines and methylphenidate to counteract uncomfortable stimulant effects?

It can be tricky: Beta blockers block only one arm of the adrenaline response that methylphenidate and/or amphetamines stir up - the Alpha adrenergic effects are not blocked, and may be relatively increased in people on beta blockers, especially hypertension. If you are getting uncomfortable stimulant effects, it would generally be better to either reduce the dose of the med or switch to constant-release form. ...Read more

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Is it possible for methylphenidate produce tolerance for amphetamines? Or the other way around?

Is it possible for methylphenidate produce tolerance for amphetamines? Or the other way around?

No: Methylphenidate and amphetamine are two different, chemically unrelated stimulants. Of the 20-30% of nonresponders to one medication, about half will respond to the other stimulant. ...Read more

Dr. Carla Enriquez
1,150 doctors shared insights

Attention Deficit Hyperactivity Disorder (Adhd) (Definition)

A bio-psycho-social disorder characterized by inattentiveness, hyperactivity, and impulsivity. ADHD typically interferes with daily functioning or mental and social development. It is usually present in childhood, continuing into adulthood, and is genetically transmitted. ...Read more


Methylphenidate (Definition)

Is the generic name of ritalin (methylphenidate). It is a ...Read more