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Doctor insights on: Methylmalonic Acid Urine

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Why would a person need a urine methylmalonic acid level test?

Why would a person   need a urine methylmalonic acid level test?

Not needed except ?: Renal disease can impair mma secretion, raising the serum levels. This test is not needed to assess B12 status unless renal insuffiency is present. Otherwise, the serum test is all that is needed! ...Read more

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Urine (Definition)

Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more


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My methylmalonic acid level is <20 is this normal? My B12 is 260 & homocysteine 12.

Yes: You have low normal b-12 levels, but with a normal methylmalonic acid and homocysteine, then you have b-12 in the body. ...Read more

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GP does not agree to a homocysteine serum Test or methylmalonic acid test. GP explains B12 Normal not low in the Range130-800pg/L My Result 155pg/L?

GP does not agree to a  homocysteine  serum Test or methylmalonic acid test.
GP explains B12 Normal not low in the Range130-800pg/L
My Result 155pg/L?

I agree: Testing involving homocysteine and one of the genes involved in its metabolism, and methylmalonic acid screens, have been heavily promoted to the public as tests that should be part of routine health care. Most of my fellow-pathologists are skeptical at best. I'd be thankful for good health as demonstrated in your serum B12 and look for some other explanation for whatever symptoms / signs you have ...Read more

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Methylmalonic acid was 115 nmol/mL and Folic acid was 24ng/mL. No reference ranges were listed. Are these normal? I have Fe deficiency anemia.

Methylmalonic acid was 115 nmol/mL and Folic acid was 24ng/mL. No reference ranges were listed. Are these normal? I have Fe deficiency anemia.

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, The data you provided indicate that you do not have folic acid or B12 deficiency. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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What should I eat or avoid if I have urine acid?

What should I eat or avoid if I have urine acid?

Normal: Urine is normally acidic and there is no need to change your diet because of that. ...Read more