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Doctor insights on: Methylmalonic Acid And Homocysteine Nutritional And Congenital

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My methylmalonic acid level is <20 is this normal? My B12 is 260 & homocysteine 12.

My methylmalonic acid level is <20 is this normal? My B12 is 260 & homocysteine 12.

Yes: You have low normal b-12 levels, but with a normal methylmalonic acid and homocysteine, then you have b-12 in the body. ...Read more

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GP does not agree to a homocysteine serum Test or methylmalonic acid test. GP explains B12 Normal not low in the Range130-800pg/L My Result 155pg/L?

GP does not agree to a  homocysteine  serum Test or methylmalonic acid test.
GP explains B12 Normal not low in the Range130-800pg/L
My Result 155pg/L?

I agree: Testing involving homocysteine and one of the genes involved in its metabolism, and methylmalonic acid screens, have been heavily promoted to the public as tests that should be part of routine health care. Most of my fellow-pathologists are skeptical at best. I'd be thankful for good health as demonstrated in your serum B12 and look for some other explanation for whatever symptoms / signs you have ...Read more

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Why would a person need a urine methylmalonic acid level test?

Why would a person   need a urine methylmalonic acid level test?

Not needed except ?: Renal disease can impair mma secretion, raising the serum levels. This test is not needed to assess B12 status unless renal insuffiency is present. Otherwise, the serum test is all that is needed! ...Read more

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Methylmalonic acid was 115 nmol/mL and Folic acid was 24ng/mL. No reference ranges were listed. Are these normal? I have Fe deficiency anemia.

Methylmalonic acid was 115 nmol/mL and Folic acid was 24ng/mL. No reference ranges were listed. Are these normal? I have Fe deficiency anemia.

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, The data you provided indicate that you do not have folic acid or B12 deficiency. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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Homocysteine 10.9 normal is lower than 10.4. B12 folic acid came back normal. So what else can cause it to be high?

Homocysteine 10.9 normal is lower than 10.4. B12 folic acid came back normal.  So what else can cause it to be high?

Stop worrying: Reference ranges are set so that a few percent of healthies fall outside. I wouldn't give that stuff another thought. A decade ago, this was being tooted as a new coronary risk factor but most of the pathologists I know disregard it. Your B12 and folate (folic acid) are fine. There's nothing you're going to do about this. It probably means nothing. * say, "Forget it." But ask your own physician. ...Read more