Doctor insights on:
Methotrexate To Treat Autoimmune Disease
It depends: Methotrexate is a potent immunosuppressive medication . It also helps reduce the need for corticosteroids that have significant side effects. Its major side effect is on the liver, causing liver damage; it can affect the lining of the gut; rarely it causes a hypersensitivity inflammation of the lung (Methotrexate pneumonitis). Therefore, patients need to be carefully monitored while on the drug, . ...Read moreSee 1 more doctor answer
Autoimmune disease is also known as Autoimmune conditions. In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more
Yes, good for many: Low dose weekly Methotrexate is an excellent and safe drug (as long as you don't drink alcohol) that is useful for treating a number of autoimmune diseases either alone or combination with other drugs. I sometimes use it in kids with an autoimmune disease where the exact diagnosis is not clear since it is excellent for long term control of inflammation without the use of steroids. Talk to your doc. ...Read more
Do you think there will be new, effective and cheap drugs within 5 years to treat autoimmune diseases?
NO- Not cheap 4 sure: I don't know if there will be new & effective drugs to treat autoimmune disease within 5 years but if there are I am certain they will NOT be cheap- hardly any new drugs are cheap; they cost a lot to develop & drug companies charge a lot of money for new drugs. But I don't think drugs are the best approach. See The Immune System Recovery Plan by Susan Blum for a better approach & my comment. ...Read more
Complex question: The term "autoimmune" means, literally, "self immune". These diseases run a wide spectrum and extend to multiple specialities. Rheumatologists deal with connective tissue diseases, gastroenterologists deal with crohn's disease, ulcerative colitis, etc..., neurologists deal with multiple sclerosis and others, and even endocrinologists treat thyroiditis and diabetes which can be immune related. ...Read more
Not even close: There are no low cost biosimilar drugs that have any value. All biologics are still under patent protection so no generics are available. ...Read more
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
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