Doctor insights on:
Methotrexate To Treat Autoimmune Disease
In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more
Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read moreSee 1 more doctor answer
Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read moreSee 2 more doctor answers
Not commonly: Unlike many meds used to treat autoimmune diseases (immune modulators that suppress the immune system) Plaquenil (hydroxychloroquine) has an antiinflammatory effect on autoimmune dss. So the risk of infections (seen with immune suppression) is uncommon. Major concern with this drug is effect on vision. Regular eye exams are recommended. ...Read more
Immunosuppressives: Big word but the goal of therapy in crohn's disease is to decrease the inflammation in the lining of the bowel. The two familes of medications used are anti-inflammatory medications - thick Motrin for the gut and immunosuppressive medications. Asa compounds such as pentasa, (mesalamine) steroids and medications such as 6-mercaptopurine and remicaide are all used based on how severe your symptoms are. ...Read more
How can you cure or treat orbital inflammatory disease besides using humira, imuran, (azathioprine) or prednisone?
IV Remicade (infliximab): You need to discuss this with your physicians and rheumatologist. The next move is IV infliximab (the brand name is Remicade). There is no FDA approved therapy for Orbital inflammatory disease and there are other choices but would feel this is the next best move. There are other choices like a different cytotoxic medication, IVIG, ...Read more
Yes. Agree, but....: Methotrexate can be very effective. However, the first studies raising the specter of liver disease came from psoriasis patients on daily low dose oral mtx!. The first pass effect is dangerous for the liver. Mtx cannot be adjudicated aqs an oral drug. Absorption is variable (40-90%), causes GI upset, and hits the liver first. I only use subcutaneous mtx once weekly. This is the safest! ...Read moreSee 1 more doctor answer
Yes: Doxycycline is the most commonly used drug for acute lyme disease but Minocycline (minocin), its close cousin, is also very effective. If someone has been recently bitten by a tick a good course of either will generally result in cure. If lyme has been present for weeks or months treatment becomes more challenging & complex. See www.Lymediseaseresource.Com/burrguide2008.Pdf for details. ...Read more
Not usually : The most common anti-inflammatories are nsaids and these are not considered immunosuppressive's. Corticosteroids may have somewhat of an immunosuppressive effect. And biologics which are used for autoimmune disease but not lyme disease can be immunosuppressive ad well as anti-inflammatory. ...Read more
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
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