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Sleep disorder in which there is inability to fall asleep &/or stay asleep, followed by daytime functional impairment. It accompanies several sleep, medical, or psychiatric disorders. It can occur at any age, but more common in elderly. It can be short-term (up to 3 weeks) or long-term. It can lead to memory impairment, mood changes, & increase risk of ...Read more
Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?
May not be best: Dysautonomia due to lupus could be due to neurological involvement such as autonomic neuropathy, or due to adrenal suppression as a consequence of prolonged steroid treatment. In the first case Methotrexate might not be a strong enough immunosuppressor; its role in lupus is mainly limited to treating arthritis. In the second case, the treatment would be supplemental steroids such as florinef. ...Read moreSee 2 more doctor answers
Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read moreSee 2 more doctor answers
Ankylosing spondylit: As treatment is to reduce inflammation , reduce and prevent complications. Rx consist of pt , breathing exercises, posture and meds .Of meds pain and nsaids are followed by dmrd which include sulfasalazine, steroids, mtx and Cyclosporine . Newer tnf blockers include embrel, humira, Remicade , tociizumab and Rituxan . Lung disease, heart (ai) , uveitis , joint replacements by specialists ...Read moreSee 1 more doctor answer
Many and quite safe!: Mtx is used in many autoimmune diseases with great effect. The drug is given IV in high doses to treat cancer. In much lower doses, given subcutaneously like insulin, with fewer side-effects than the same oral dose, does not go to the liver. And you absorb 100%, not the 40-90% when taken by mouth. Great drug. Ist line in ra! ...Read moreSee 1 more doctor answer
A mainstay for...: The treatment of rheumatoid arthritis and psoriatic arthritis, and other inflammatory conditions! i administer to my patients mtx by the subcutaneous route, thereby insuring 100% absorption and bypassing stomach and liver. When given with folic acid, i rarely see significant problems for my patients! ...Read moreSee 1 more doctor answer
If i took 1st dose of methotrexate 10mg weekly last friday, can I take it 1-2 days early to switch to wed or thursays from now on?
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
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