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Doctor insights on: Methotrexate Headaches Excedrin Harm

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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I'm 12 weeks pregnant I took a Excedrin for my headache.. dis I harm my baby?

I'm 12 weeks pregnant I took a Excedrin for my headache.. dis I harm my baby?

Probably not: But a good policy is: you should always check with your OB Doc BEFORE you take any medicines incuding over the counter medicines ESPECIALLY in your first trimester. ...Read more

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Why do methotrexate pills harm the liver?

Why do methotrexate pills harm the liver?

Mechanisim of med: Methotrexate pills are broken down in the liver and effect several liver enzymes. You can get the specific details in Kelly's textbook of Rheumatology or a pharmacology text. This effect is multiplied by alcohol which should be avoided when you take methotrexate. ...Read more

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I've randomly got a severe headache and under when to worry section on google says when ur on immuno suppressants get checked out im on methotrexate?

I've randomly got a severe headache and under when to worry section on google says  when ur on immuno suppressants get checked out im on methotrexate?

Lo dose methotrexate: A severe headache could be a symptom of a life threatening infection such as meningitis, but if you are taking low dose Methotrexate for arthritis, or psoriasis, the chances of meningitis are virtually zero. None the less, you should discuss your headaches with your doctor. ...Read more

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Methotrexate is harming my liver and i can't afford biologic meds. What can I do ?

Methotrexate is harming my liver and i can't afford biologic meds. What can I do ?

See details: You can switch to the subcutaneous form of Methotrexate as this may be less likely to cause liver toxicity. You can try Arava (leflunomide) although there is also a risk of toxicity with this med. Then there is a combination of Plaquenil (hydroxychloroquine) and sulfasalazine. ...Read more

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Does methotrexate affect the.Eyes? If yes how can it be prevenred from.Harming the eye?

No: Methotrexate does not harm the eyes in any way. In fact, low dose weekly Methotrexate is an excellent treatment for autoimmune inflammation of the eyes (called uveitis). It is actually much safer than long term steroids (eye drops or oral) since long term use of steroids can cause cataracts and other eye problems. ...Read more

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Dr. Bennett Machanic
4,158 doctors shared insights

Headache (Definition)

The medical term is cephalalgia. It is a feeling of pain that can occur on either both sides or just one side of the head or neck. Headaches can be sharp, dull, or throbbing, and can radiate to different areas of the head. They typically last less than an hour but can ...Read more


Dr. Robert Lowe
329 doctors shared insights

Rheumatrex (Definition)

Rheumatrex ...Read more