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Doctor insights on: Methotrexate H Cg Increase After Second Dose

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I had a d&c on 1/14 at 9.5 wks. My hCG has been going down but has plateaued at about 2. My doc wants to give me methotrexate. Is it really necessary?

I had a d&c on 1/14 at 9.5 wks. My hCG has been going down but has plateaued at about 2. My doc wants to give me methotrexate. Is it really necessary?

Undetectable HCG: The level at which an HCG is considered undetectable can be different between different institutions. However i would think that a level of two (usually anything less than 3miu/ml) is undetectable and therefore a negative test, thus not warranting methotrexate. I would discuss this further with your doctor as Methotrexate is not benign. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Is it safe to go on the hCG diet while taking methotrexate for sle?

Probably ok but....: It is probably ok but don't do it. Methotrexate is an extremely potent medication with lots of side effects. ...Read more

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I was just given a methotrexate shot at 6wks with hCG my levels at 670. When will i start bleeding and cramping?

Any time is possible: There is no set time to expect bleeding and cramping. However, weekly measurements of your bhcg levels need to be obtained to make sure you are responding appropriately. ...Read more

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Missed miscarriage, 6.5 wks took cytotec at 11wks to abort. 6wks later HCG 59, had methotrexate. 3wks later still have HCG of 34. Why wont it go down?

It should over time: Methotrexate causes slow deterioration of the HCG producing chorionic villi and as a result serial HCG's are done to note if the result is trending downward or not. ...Read more

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4 hCG levels over 10 days stay around 2500. 2 vag. Ultrasounds show no sign of pregnancy. Is methotrexate a reasonable option to d&c?

4 hCG levels over 10 days stay around 2500.  2 vag. Ultrasounds show no sign of pregnancy.  Is methotrexate a reasonable option to d&c?

?: You are asking a serious question that may have many pitfalls. You need to talk to an ob-gyn who knows your medical history to get informed advice from an expert. ...Read more

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I had a positive pregnancy test . Hcg was 330 48h after 454 and 48h after 660 i might have a methotrexate injection can I go to work the day after?

Methotrexate injecti: These injections are well tolerated, produce minimal if any side effects. So you should be able to go to work fine. ...Read more

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Why hcg levels rise after methotrexate shot? is it normal for Hcg levels to drop frm 9000 to 1000 after MTX in 1 wk for supposed ectopic?

Bhcg : the Bhcg often rises the first few days after treatment with methotrexate for an act topic pregnancy. Typically a level is checked on day four. This establishes the baseline. Then we expect to see at least a 15% drop between day for an day seven. A larger drop is even better ...Read more

Dr. Robert Lowe
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Rheumatrex (Definition)

Rheumatrex ...Read more