Doctor insights on:
Methotrexate And Shingles
Not a good idea: The shingles vaccincation (known as zostervax) is a live virus, therefore you would run the risk of infection from the vaccination itself. Any medication in the class of drugs like Humira (adalimumab) would be a no-no to receiving the shingles vaccine. This is the official published guidelines from rheumatologists that just came out in early 2012. ...Read moreSee 1 more doctor answer
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Better to be on methotrexate and hydroxychloroquine or methotrexate and a biologic when treating jra? Methotrexate only doesn't help
Depends on severity: Since you have already been on Methotrexate and its not helping you get complete relief from symptoms, further addition of therapies will depend on severity of your current symptoms. Hydroxychloroquine is milder in efficacy as compared to biologics & both have different side effect profiles. Talk to a rheumatologist who can assess your clinical course & treatment needs & then advise accordingly. ...Read moreSee 1 more doctor answer
Daughter on methotrexate and enbrel and indocin for JRA but hates getting shots every week. Could remicade (infliximab) be a better choice?
Dose dependent: This judgement has to be made by the provider. Technically low dose Methotrexate is not considered a contraindication to receiving the shingles vaccine. But only your provider will have a full picture of your immune status. Shingles vaccine is a live vaccine and not given to those with significant immunosuppression. ...Read more
On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.
Follow laboratory: You are correct that liver problems are risk with this regimen. Your physician needs to be certain that you are followed closely and correctly. Your own responsibility is to refrain from alcohol, and be certain no additional medicines you take do not worsen this risk. If you are concerned you need to discuss this with your physician. There are other therapy choices available. ...Read more
Yes.: My colleagues believe it is the first choice (acr and eular), but while I use it as a second or third drug, the benefit/risk ratio is incredibly good. Methotrexate has little or no justification to be taken orally though. Unpredictable absorption, stomach concenbration build up, and going to the liver on first-pass! the liver sees 600x the ultimate concentration in the blood. ...Read more
On enbrel 50mg weekly for 3 mos, methotrexate 25mg weekly 3mos, arava (leflunomide) 20mg 1 month, still have psoriasis lesions.Is this possible&willl psor. Ever clear?
Still a bit early: So many of these medications requires several weeks or months to start working. Enbrel and Arava usually works around 3 months after starting it, and Methotrexate can take as long as 6 months before working. I would give it another month, then reconsider. There are other good medicines that could work for you including stelara (ustekinumab). ...Read more
My anti ccp is 300 , am taking 17.5 mg mtx and will start soon a combination of enbrel (etanercept) and mtx is that good ?
Combination therapy: Rheumatoid arthritis should be diagnosed and managed by a trained rheumatologist. The anti-ccp antibody is highly specific for RA. Methotrexate, in combination with other medications, can often successfully treat RA and prevent joint damage. Sometimes, MTX is combined with sulfasalazine and hydroxychloroquine. Alternatively, a "biologic" agent is added such as Etanercept (Enbrel), which blocks TNF ...Read moreSee 1 more doctor answer
Since starting Accutane i've experienced more frequent herpesvirus outbreaks consisting of more lesions. Why? Valtrex (valacyclovir) and Accutane together?
Possibly related: There are some reports in the literature of increased h. Simplex perioral outbreaks with Isotretinoin use. Some dermatologists recommend pre-treatment with herpecidal medication (such as valtrex) for one week prior to starting Isotretinoin in those with a history of outbreaks. ...Read more
Have taken enbrel (etanercept) 50 mg sq x 10 weeks for RA + psoriasis. Ra barely better. Psoriasis worse. Would enbrel (etanercept) 2x per week help the psoriasis and RA or not?
For rheumatologists, my mom's dr prescriped methotrexate, HQ, and prednisone plus Humira (adalimumab) q2wks for her RA..is that very strong drugs on her or normal?
"Normal" Combination: That is a reasonable combination.Get a more detailed answer ›
Yes: If i understand correctly, the answer is yes; it is normal to get shingles at age 35, or even younger. Shingles is caused by the "sleeping" chicken pox virus becoming active and causing a painful blistering rash, at most any age. The shingles vaccine, recommended at age 60 or over, reduces the risk by about 50%. A good prevention resource is an iphone/ipad app called prevention checklist 2013. ...Read more
Do medications (eg: lyrica, (pregabalin) prednisone, methotrexate, azathioprine) have any effect on a skin test for small fiber neuropathy?
How serious is staphylococcal folliculitis for someone on methotrexate and remicade (infliximab)?
Realistically, how long before, plaquinil, imuran, (azathioprine) and low dose prednisone, should control a lupus flare. I'm at 3 months starting to get discourage. ?
Shingles (Herpes Zoster) (Definition)
A painful blistering skin rash caused by the chickenpox virus (varicella zoster), occurring in people who have had chicken pox some time in their past. ...Read more
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