Doctor insights on:
Methotrexate And Shingles
Dose dependent: This judgement has to be made by the provider. Technically low dose Methotrexate is not considered a contraindication to receiving the shingles vaccine. But only your provider will have a full picture of your immune status. Shingles vaccine is a live vaccine and not given to those with significant immunosuppression. ...Read more
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
My RA doc recommended stopping my wkly sunday dose of 20 mg methotrexate, getting my shingles vaccine monday, resume next sun dose. Is 20 a low dose?
The dosage is vary and will be different for different patients. Do not adjust the dose by yourself. Take this medicine only as directed by your doctor.
If concern, is always good to ask your physician. ...Read more
2 months: The recommendation is 2 months.Get a more detailed answer ›
Can I get the shingles shot while being on methotrexate, or should I not get the? What's the pros and cons?
Is it possible for new shingles lesions to erupt after finishing a 7 day course of an antiviral drug? I have RA and diabetes and I am on methotrexate.
No as a general rule: Its best to offer live vaccines such as zostavax prior to initiating therapy with immunosupressive agents. Combination of Rituximab with a live vaccine may cause more harm than good. In rare cases, only your doctor can decide if the benefit of this vaccine outweighs the potential risks. If feasible, Rituximab may be stopped for a few months prior to administering live vaccine. ...Read more
Would you recommend the shingles vaccine for a 65 year old patient taking 7.5mg methotrexate once weekly for rheumatoid arthritis?
Hello~ ZOSTAVAX +65yo + MTX??
ANSWER: YES ABSOLUTELY DEFINITELY
THANKS ...Read more
Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read more
Yes: NSIDs can be taken with Methotrexate. With or without Methotrexate, NSAIDs have many possible side effects and need to be used carefully. Gastrointestinal issues such as ulcers/gastritis can occur. Studies continue to show NSAIDs are associated with increased risks of cardiovascular side effects such as heart attacks and strokes. Routine labs are needed to watch for other side effects of both meds ...Read more
Methotrexate is a medicine that treats several kinds of cancer, including cancer of the blood, bone, lung, breast, head, or neck. Also treats rheumatoid arthritis and psoriasis (a skin disease).
Fluconazole prevents and treats certain fungus infections. Belongs to a class of drugs called antifungals. ...Read more
Methotrexate cheaper: Generic Methotrexate is very inexpensive. If you get name brand pills it's more, but generic version of Arava (leflunomide) is more expensive than Methotrexate and Arava is the most expensive. In my experience, Methotrexate works better and has less frequent dosing (weekly instead of daily). I only use Leflunomide (arava) if Methotrexate can't be used for some reason. Side effects are similar. ...Read more
Not a good idea!: Wait!Get a more detailed answer ›
Shingles (Herpes Zoster) (Definition)
A painful blistering skin rash caused by the chickenpox virus (varicella zoster). Early treatment with antiviral medication (within 72 hours) lowers the risk of post-herpetic neuralgia, which is lingering skin pain after the rash disappears. ...Read more