Doctor insights on:
Methotrexate And Pancreatitis
I have Crohn's and have been on pentasa, (mesalamine) humira and imuran which severely increase my liver enzymes. Would remicade be less liver toxic then imuran?
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Persistently high ggt, why? Alt sometimes high. Sle sufferer. Liver biopsy, gallbladder, blood tests normal. On plaquenil and cellcept (mycophenolate mofetil). No alcohol.
Liver function: Tests could become elevated from any number of things, most commonly from medications or alcohol, or even blunt external injury. If your liver biopsy is completely normal, you probably should not worry too much. Ask your doctor for specific recommendation. ...Read moreSee 1 more doctor answer
What are my chances of getting liver disease while taking arava (leflunomide) and methotrexate together?
See details: Studies of this combination have shown increased risk of liver disease over taking just one of these meds alone. The exact risk is open to debate. I personally never prescribe this combination of meds although other rheumatologists do. ...Read more
Is my pancreatitis autoimmune pancreatitis as i have no pain with elevated serum and urine amylase levels no pain.
Fatty liver and hypothyroid ok to take metformin even with gallstones?No attack of gallstones so far
After an emergency cholecystectomy, pancreatitis, and liver disease, i was diagnosed with sle. Did the lupus cause all that damage?
Can I use methotrexate to treat psoriatic arthritis when I also have gallbladder stones and severe attacks?
Yes, but...: ...Why are you enduring the pain and risk of frequent gallbladder attacks? In the modern era of minimally invasive surgery, the risks are often greater to continue to have gallbladder attacks rather than the risk of surgery. Have you spoken with your primary care physician or rheumatologist about these attacks? ...Read moreSee 2 more doctor answers
Met colon cancer pt with liver mets . Has enteritis so on antibiotics .
Fever , nausea and bilirubin fluctuating up and down... Can
This be liver failing ?
Yes: if the bilirubin is going up, then the liver is obstructed and cannot get rid of it and.. is failing but can be fixed perhaps by putting a tube through to the intestines. If the liver enzymes are elevated and the proteins the liver puts out (albumin and clotting proteins) are low, then it is failing. ...Read more
Taking cyclosporine and cellcept (mycophenolate mofetil) due to liver transplant, can I take SUKROL ( glutamic acid ), my memory and concentration been decreased lately. ?
Don't take it.: Sukrol is an OTC supplement containing multiple ingredients, including glutamic acid, lecithin, and thiamine. It is impossible to predict whether any of these could have an interaction with your cyclosporine or CellCept (mycophenolate mofetil). Given the potentially dire consequences of an interaction, it is not worth it to take your chances with an unproven supplement. Good luck. ...Read more
I take nabumetone, methotrexate, enbrel, plaquenil, vitamin d and folic acid for RA & dermatomyo. Which of these is making it difficult to lose wight?
Take propecia 1mg, methotrexate 25mg, arava (leflunomide) 20mg, enbrel weekly, B12 & folic acid..Which ones are most likely to cause high liver enzymes(ast&alt)?
Idiopathic recurring pancreatitis, no alcoholism, gallstones, pain, high triglycerides. Only elevated amylase and lipase. What is next step?
See your doctor soon: It is wise to see your doctor soon regarding this. Depending on how high your amylase and lipase are it could be acute or chronic pancreatitis, and considering that you're on medications and have a history of acute pancreatitis, it's even more important to see your doctor. Diet restrictions like low fat intake and fluid replacement and monitoring are needed to be done, so see dr. Asap. ...Read moreSee 2 more doctor answers
Why does serum lipase and amylase increase during acute pancreatitis? Shouldn't it decrease since there is problem with pancreas (inflammation)?
Lipase serum levels: I believe the reasons both rise in the bloodstream is because there is disruption of the pancrease (pancrelipase) and these enzymes get into the blood stream. They are both part of the exocrine function and should not be in the blood steam. The endocrine portion of the organ involves insulin production. This chemical is supposed to be in the blood. The other are designed to be released into the duodenum . ...Read more
Diagnosed with acute alcohol induced hepatitis and early cirrhosis denied a liver transplant bleeding and infection are risks. On dialysis--prognosis?
Still drinking?: Acute liver injury due to alcohol use is unlikely to have a good outcome unless abstinence occurs. That is the only chance of surviving. The kidney injury may improve - insufficient info to respond. Top priority now is alcohol abuse treatment. - for long term prognosis. ...Read moreSee 1 more doctor answer