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Doctor insights on: Methotrexate And Neuropathy

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Dr. Olav Jaren
1,343 Doctors shared insights

Nerve Damage (Definition)

A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more


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What treats neuropathy?

What treats neuropathy?

Most Rx limited help: The central nervous system is made up of the brain and the spinal cord; all the nerves to the rest of the body stem from the cns, and is called peripheral nervous system; neuropathy (n) is a disorder of the peripheral nerves. Examples are diabetic neuropathy, alcohol-induced n. And carpal tunnel, a n. Of the median nerve in the wrist. Gabapentin, lyrica, (pregabalin) tegretol etc may help but no cures, yet. ...Read more

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How to manage neuropathy?

How to manage neuropathy?

Nerve symptoms: Peripheral neuropathy can be secondary to numerous causes. It is best to uncover the cause and treat directly. To treat symptoms, doctors might use gabapentin, lyrica, (pregabalin) or cymbalta, but a medical food such as metanx might be useful. ...Read more

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Best thing for neuropathy?

Find the cause: The best treatment for neuropathy is to treat the cause (for diabetic neuropathy: control blood sugars, lose weight. For thyroid-related neuropathy, optimize thyroid medication dose. For B12 deficiency, replace lost vitamin b12. For toxic neuropathy, drink no alcohol; etc). Prescription medications for neuropathy do not cure the condition or heal the nerves, they only help alleviate nerve pain. ...Read more

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Does neuropathy come and go?

Does neuropathy come and go?

Yes: Almost any disease process has its ups and downs, especially dependent upon the cause of the neuropathy. ...Read more

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Different types of neuropathy?

Different types of neuropathy?

Way too broad: That question can't possibly be answered in 400 characters, or 400 words, or 400 lines, or even, if you're a neuroscientist, in 400 pages. Some researchers spend their entire careers studying just one type of neuropathy. If you want to educate yourself, I recommend starting at http://www. Neuropathy. Org. ...Read more

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What are diabetic neuropathies?

What are diabetic neuropathies?

Poor nerve function: Nerve disease/damage thought to be caused by poor blood supply to nerves &/or high blood sugar. There are 2 types of neuropathy: peripheral and autonomic. Peripheral causes loss of feeling in hands/feet, weakness & imbalance. This can lead to wound development & possible amputation. Autonomic leads to heart problems, problems w/ body temp, erectile dysfunction, dry skin, & digestive problems. ...Read more

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What are the symptoms of neuropathy?

What are the symptoms of neuropathy?

Numbness, pain, weak: Just as there are many causes for neuropathy, there are many symptoms as well. Neuropathy can cause numbness, pain (typically with a burning or electrical quality), or weakness. It can also cause imbalance (due to inability to feel in the feet) as well as blood pressure problems (because of loss if innervation of the heart and blood vessels). ...Read more

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Is it o.K. To tan while on methotrexate?

Is it o.K. To tan while on methotrexate?

No: While this is actually unlikely to cause problems, sunburn may be more likely while using methotrexate. Though it may depend on why and how you're using it. ...Read more

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What foods should I avoid for neuropathy?

No specific foods: While no foods will improve your neuropathy, unless you have a vit b deficiency, keeping the factors that caused the neuropathy in control are most important. For example, patients with diabetic neuropathy need to keep their sugars under control to decrease the risk of progression of their neuropathy. Diabetics should try eating healthier, lower glycemic foods. Hope that helps! ...Read more

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What does the pain feel like in neuropathy?

What does the pain feel like in neuropathy?

Burning tingling: Sensory neuropathy is broken down into large fiber (loss of sensation, loss of proprioception) and small fiber (burning, tingling sensation). It's the small fiber component that most patients complain about. They also relate sensation of ants crawling on their feet and legs. ...Read more

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What are the different kinds of neuropathy?

What are the different kinds of neuropathy?

Many types: There are many types of neuropathy, many associated with other disorders. Just a few. Acute motor, subacute sensorimotor, asymmetric polyneuropathies, chronic sensorimotor polyneuropathies, inherited polyneuropathies of mixed sensorimotor types-idiopathic type, metabolic type, neuropathy with mitochondrial disease, relapsing polyneuropathy, mononeuropathy/plexopathy. Some examples in topic tags. ...Read more

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Please describe the medication: methotrexate?

Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read more

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What are the presenting symptoms of neuropathy?

Pain and numbness,: These are the most common symptoms of polyneuropathy:
tingling
numbness
loss of sensation in the arms and legs. ...Read more

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How to treat neuropathy?

How to treat neuropathy?

Many ways: Neuropathy in of itself can be related to many different disease processes, such as diabetes. Improved control of the disease process may result in some improvement in the neuropathy symptoms. Other treatments may include meds in anti-seizure class that act to "calm" over active nerves causing discomfort. If refractory to meds and conservative tx, neuromodulation through spinal cord stimulation. ...Read more

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Is there any cure for neuropathy?

Is there any cure for neuropathy?

Depends: There are many causes of neuropathy, including diabetes, B12 deficiency, alcohol, autoimmune (lupus, rheumatoid, vasculitis), heavy metal toxicity, chemotherapy, nerve entrapment. Many forms of neuropathy can be treated and pain can be reduced or eliminated. Treatment depends on the cause. ...Read more

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Is tanning ok while on methotrexate?

Is tanning ok while on methotrexate?

Yes, but: Tanning ages skin and causes cancer. But that having been said, Methotrexate does not make tanning more dangerous! ...Read more

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What exactly is alcoholic neuropathy?

Poisoned nerves: Long term use of excessive alcohol causes nerve damage. The symptoms can be burning pain, tingling sensation, numbness, or weakness. Other symptoms of alcohol polyneuropathy include problems with walking, blood pressure that drops too much when standing causing lightheadedness/fainting. Symptoms are worse when there is also vitamin deficiency such as thiamine deficiency, which can cause dementia. ...Read more

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I'm having issues describing neuropathy to a teacher?

What are you saying: Neuropathy refers to damage to nerves and in the case of peripheral neuropathy nerve of the peripheral nervous system. This may be caused either by diseases of or trauma to the nerve or the side-effects of systemic illness. There are central neuropathies also which can be related to the damage to the nerves of the central nervous system. Are you saying this to the teacher? ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


Dr. Bennett Machanic
1,459 Doctors shared insights

Neuropathy (Definition)

Weakness, numbness, and pain from nerve damage, usually in ...Read more