Doctor insights on:
Methotrexate And Exercise
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Need more info: Methrotrexate is used for many diseases. Please ask this question again and be specific about what the Methotrexate is being used for.
Many: Methotrexate toxicity can take many forms, from extreme mucositis, low blood counts, and kidney damage. If Methotrexate is given intrathecally (into spinal csf) as is done to treat leukemia, it can sometimes cause toxicity to the brain, which can manifest itself as seizures. Methotrexate can also affect the liver and lungs. If you are having new symptoms, talk with the prescribing doctor.
Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases.See 2 more doctor answers
Yes: Mtx appears to be safe for long term use if side effects are mild. However, many patients have other treatments in addition to mtx which may affect levels and require monitoring for toxicity, .See 1 more doctor answer
Depends on…: Dose & how long you were on it. Mtx's half life (amount of time for active med to be reduced by 1/2) is given as 3-15 hours but varies according the dose. It takes at least 4-5 half lives for a drug to be eliminated from the system, assuming there is normal liver & kidney function.
See details: It is given as a subcutaneous injection, similar to an insulin shot. The discomfort is very minimal. If you have any other questions, list them.
Many and quite safe!: Mtx is used in many autoimmune diseases with great effect. The drug is given IV in high doses to treat cancer. In much lower doses, given subcutaneously like insulin, with fewer side-effects than the same oral dose, does not go to the liver. And you absorb 100%, not the 40-90% when taken by mouth. Great drug. Ist line in ra!See 1 more doctor answer
A mainstay for...: The treatment of rheumatoid arthritis and psoriatic arthritis, and other inflammatory conditions! I administer to my patients mtx by the subcutaneous route, thereby insuring 100% absorption and bypassing stomach and liver. When given with folic acid, I rarely see significant problems for my patients!See 1 more doctor answer
Exercise Or Physical Activity (Definition)
Exercise is a physical activity that is completed to maintain or improve health. Benefits of exercise include weight maintenance, improving mood, increasing energy, preventing or controlling chronic diseases, promoting better sleeping, and improving sex life and libido. ...Read more