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Doctor insights on: Methotrexate And Bactrim

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I'm on methotrexate, can I still drink?

I'm on methotrexate, can I still drink?

Absolutely NOT!: The combination of alcohol and Methotrexate has caused many people to have liver failure requiring a liver transplant to survive. Methotrexate can irritate the liver by itself but is quite safe at the low weekly doses used to treat many autoimmune conditions.Never drink any alcohol while on methotrexate. If you absolutely "must" drink alcohol, tell your doc so he/she can take you off methotrexate. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Can I take cold medication if I'm taking methotrexate.?

See below: As a good rule of thumb, if you have an infection, you would want to leave off your Methotrexate and Imuran (azathioprine) and when the infection resolves, you can resume them. ...Read more

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I'm on drug trial for toccilizumab with methotrexate, what to do about liver problems?

I'm on drug trial for toccilizumab with methotrexate, what to do about liver problems?

You will be monitore: Your will be monitored in the trial for liver problems. Each of these drugs methotrexate and tocilizumab can possibly cause liver problems. The trial protocol will decide about medication dose adjustment. You may have no liver problems with either of these. ...Read more

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My age is 29yrs. For psoriasis, I'm taking methotrexate 7.5 mg since 7yrs. Using this, what are the side effects to me in long term. Plz suggest?

Probably not much: This is a small dose of methotrexate. Assuming you have blood tests to screen for medication toxicity and these tests are normal, the long term risk is small. Make sure blood is screened for liver toxicity and reduced blood counts every 3 months. ...Read more

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I have stopped taking my Crohn's medication (methotrexate)i was suffering severe side effects. I'm still incredibly sick & wondering when it will stop?

I have stopped taking my Crohn's medication (methotrexate)i was suffering severe side effects. I'm still incredibly sick & wondering when it will stop?

Could be Crohn's: Some of the most common side effects can be similar to symptoms of crohn's. These include mouth sores, fever, diarrhea, blood in your stools, body aches and abdominal pain. You may want to check with your doctor and make sure this is not a flare up of your disease. ...Read more

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Is it o.K. To tan while on methotrexate?

Is it o.K. To tan while on methotrexate?

No: While this is actually unlikely to cause problems, sunburn may be more likely while using methotrexate. Though it may depend on why and how you're using it. ...Read more

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Please describe the medication: methotrexate?

Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read more

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Any methotrexate side effects?

Any methotrexate side effects?

Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid. ...Read more

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Can methotrexate treat psoriasis?

Can methotrexate treat psoriasis?

Yes. Agree, but....: Methotrexate can be very effective. However, the first studies raising the specter of liver disease came from psoriasis patients on daily low dose oral mtx! . The first pass effect is dangerous for the liver. Mtx cannot be adjudicated aqs an oral drug. Absorption is variable (40-90%), causes GI upset, and hits the liver first. I only use subcutaneous mtx once weekly. This is the safest! ...Read more

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Is it harmful to take methotrexate?

Is it harmful to take methotrexate?

Yes, if no indicatio: It will be harmful if no indication to take. However, if there is a strong indication- it is something that is tolerable. Just like any other medication, there will be some possible adverse events- and this is something that you have to discuss with your doctor- to weigh the benefit and the risk and make a decision. ...Read more

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Is tanning ok while on methotrexate?

Is tanning ok while on methotrexate?

Yes, but: Tanning ages skin and causes cancer. But that having been said, Methotrexate does not make tanning more dangerous! ...Read more

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Is methotrexate safe to use with CKD?

Avoid using Abbrevia: What is CKD? Is it chronic Kidney disease? If so, what is your kidney function in terms of your blood Creatinine levels? . What is the cause? Methotrexate is not safe to use for patients with kidney diseases.
Please clarify, so that we can guide you further. ...Read more

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Should I take methotrexate if I have a cold?

See details: When in doubt it is always prudent to skip a week. This question is best directed to the doctor who is prescribing it. ...Read more

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How well does methotrexate work on psoriasis?

How well does methotrexate work on psoriasis?

Psoriasis: Methotrexate is a terrific therapy for severe psoriasis. It works well, is very inexpensive and is relatively safe when its effects are carefully monitored. ...Read more

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Need to know about a drug called methotrexate?

Need to know about a drug called methotrexate?

Folic acid inhibitor: It inhibits Folic Acid and can help treat inflammatory disorders like rheumatoid arthritis, psoriasis, tumors, etc, it can help vasculitis also whether it is due to an inflammatory or infectious etiology. It needs to be carefully monitored, can cause liver disease so we recommend no alcohol, can cause low blood counts and mouth ulcers and hair loss so we supplement therapy with folic acid. ...Read more

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Can methotrexate help herpes or cause a out break?

Outbreak...: Methotrexate is an immunosuppressive drug and is not an antiviral compound. Thus some patients can have flares of viruses like herpes or varicella (chickenpox and shingles) when they receive Methotrexate because their white blood cell numbers and/or activity are decreased. ...Read more

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What are some of the side effects of methotrexate?

Several.: Fatigue after taking your weekly dose. Gi quiziness. Hair loss. Potential liver issues, especially taken orally. Your white count can be lowered, as well as hemoglobin. Everyone on mtx should take folic acid. Monitoring for side effects (benefits too) should take place every three months or sooner. ...Read more

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Bactrim (Definition)

Trimethoprim and sulfamethoxazole, cotrimoxazole is a combination antibiotic that is used to treat a ...Read more


Dr. Robert Lowe
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