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Doctor insights on: Methotrexate And Alopecia

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Can psoriasis and alopecia areata occur together?

Can psoriasis and alopecia areata occur together?

Of course: While this is not common, they are both autoimmune disorders. Anyone with one of these has a greater than average risk of having the other. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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I was diagnose with alopecia areata. My dermatologist prescribed clobetasol.Is topical ic clobetasol .05 okay to treat hair loss in women?

I was diagnose with alopecia areata. My dermatologist prescribed clobetasol.Is topical ic clobetasol .05 okay to treat hair loss in women?

Any prescription....: ...Medicine should be used only by the person for whom it was prescribed, and for the purpose for which it was prescribed. Not for anything else, and not by anyone else. ...Read more

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Better to be on methotrexate and hydroxychloroquine or methotrexate and a biologic when treating jra? Methotrexate only doesn't help

Better to be on methotrexate and hydroxychloroquine or methotrexate and a biologic when treating jra? Methotrexate only doesn't help

Depends on severity: Since you have already been on Methotrexate and its not helping you get complete relief from symptoms, further addition of therapies will depend on severity of your current symptoms. Hydroxychloroquine is milder in efficacy as compared to biologics & both have different side effect profiles. Talk to a rheumatologist who can assess your clinical course & treatment needs & then advise accordingly. ...Read more

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On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.

On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.

Follow laboratory: You are correct that liver problems are risk with this regimen. Your physician needs to be certain that you are followed closely and correctly. Your own responsibility is to refrain from alcohol, and be certain no additional medicines you take do not worsen this risk. If you are concerned you need to discuss this with your physician. There are other therapy choices available. ...Read more

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Can beetroot reduce methotrexate side effects in a psoriasis and psoriatic arthritis patient?

Can beetroot reduce methotrexate side effects in a psoriasis and psoriatic arthritis patient?

Not really!: Beet root is high in folic acid, but we routinely give Folic Acid to patients on methotrexate, usually 2mg/day. This would be overkill, and add unnecessary expense! ...Read more

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
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Do etoposide and cisplatin cause alopecia?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Do etoposide and cisplatin cause alopecia?

Yes: Yes, the regimen will give you alopecia. ...Read more

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Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?

Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read more

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Hair loss from imuran (azathioprine) or prednisolone more likely? Stopped imuran (azathioprine) (100mg)still on prednisolone (20mg).Is there anything i can do to reduce loss please

Potential relapse: I see from your history you have ulcerative colitis. Every medicine i know can cause hair loss insurance is a very powerful immunosuppressive medication. This could precipitate flair of ulcerative colitis. Ulcerative colitis if it has been bad could also precipitate hair loss. Would discuss with managing physician before interrupting or altering these medications. ...Read more

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On enbrel 50mg weekly for 3 mos, methotrexate 25mg weekly 3mos, arava (leflunomide) 20mg 1 month, still have psoriasis lesions.Is this possible&willl psor. Ever clear?

On enbrel 50mg weekly for 3 mos, methotrexate 25mg weekly 3mos, arava (leflunomide) 20mg 1 month, still have psoriasis lesions.Is this possible&willl psor. Ever clear?

Still a bit early: So many of these medications requires several weeks or months to start working. Enbrel and Arava usually works around 3 months after starting it, and Methotrexate can take as long as 6 months before working. I would give it another month, then reconsider. There are other good medicines that could work for you including stelara (ustekinumab). ...Read more

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I'm 59 and dx with UCTD three years ago. I have been taking plaquenil (hydroxychloroquine) for 16 months. Could plaquenil (hydroxychloroquine) contribute to thinning hair?

I'm 59 and dx with UCTD three years ago. I have been taking plaquenil (hydroxychloroquine) for 16 months. Could plaquenil (hydroxychloroquine) contribute to thinning hair?

Yes, and...: Hair loss was listed as one of its side effects as detailed in http://www.webmd.com/drugs/2/drug-6986/plaquenil-oral/details#side-effects. Based on your clinical profile, you have been struggling for bettering your life. To help reach such goals, perusing articles in http://formefirst.com/eNewsletter06.html, http://formefirst.com/eNewsletter.html, & http://formefirst.com/eBlogList.htmlm may help. ...Read more

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Dx w/ lcv- plaquenil (hydroxychloroquine) and colcrys kept at bay. I've gained weight & considered "obese"-began w/flares again. Can that be a factor?

Dx w/ lcv- plaquenil (hydroxychloroquine) and colcrys kept at bay. I've gained weight & considered "obese"-began w/flares again. Can that be a factor?

LCV: Rx Issues: The issue with Plaquenil (hydroxychloroquine) is not your total weight, but your lean body mass (lbm). You may weigh 160 lbs, but your lbm might be only 120. The less the lbm, the greater the danger of Plaquenil (hydroxychloroquine) toxicity, including retinal and liver problems. This is a complex problem, and you should definitely seek immediate evaluation by your provider and follow up to avoid exacerbating your vasculitis or eye probs. ...Read more

Dr. Emily Altman
585 doctors shared insights

Baldness (Definition)

Baldness is a lack of hair on the scalp (it could ...Read more


Dr. Robert Lowe
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Rheumatrex (Definition)

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