Top
10
Doctor insights on: Methotrexate

Share

Methotrexate (Overview)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases.


1

1
What are methotrexate and fluconazole?

What are methotrexate and fluconazole?

Meds: Methotrexate is a medicine that treats several kinds of cancer, including cancer of the blood, bone, lung, breast, head, or neck. Also treats rheumatoid arthritis and psoriasis (a skin disease). Fluconazole prevents and treats certain fungus infections. Belongs to a class of drugs called antifungals. ...Read more

Methotrexate (Overview)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases.


2

2
Please describe the medication: methotrexate?

Please describe the medication: methotrexate?

Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read more

See 2 more doctor answers
3

3
Are there more risks or benefits with use of weekly methotrexate as injection vs oral for arthritis or ctds. Why is oral usually prescribed?

Are there more risks or benefits with use of weekly methotrexate as injection vs oral for arthritis or ctds. Why is oral usually prescribed?

No: There is no increased risk in fact many believe the injectable form is better as it gets directly into bloodstream and does not depend on absorption from the gut. ...Read more

See 1 more doctor answer
4

4
My mother have rheumatoid arthritis and her doctor prescribed methotrexate & adalimumab (sub-q), did this combination too heavy for health or normal?

My mother have rheumatoid arthritis and her doctor prescribed methotrexate  & adalimumab (sub-q), did this combination too heavy for health or normal?

No: This is appropriate combination therapy for uncontrolled ra. The benefits of these meds in preventing joint damage and disability far outweighs the risks. ...Read more

See 1 more doctor answer
5

5
Can I use methotrexate to treat psoriatic arthritis when I also have gallbladder stones and severe attacks?

Yes, but...: ...Why are you enduring the pain and risk of frequent gallbladder attacks? In the modern era of minimally invasive surgery, the risks are often greater to continue to have gallbladder attacks rather than the risk of surgery. Have you spoken with your primary care physician or rheumatologist about these attacks? ...Read more

See 2 more doctor answers
6

6
Can the typical dose methotrexate used for lupus increase ones chance of developing cancer? I'm worried about it. How many years is it "safe" to be on?

Can  the typical dose methotrexate used for lupus increase ones chance of developing cancer? I'm worried about it. How many years is it "safe" to be on?

Very, very, unlikely: The dose is so small on the doses of mtx used for other things, other than arthritis an autoimmune diseases, it is something you should not worry about! ...Read more

See 1 more doctor answer
8

8
How well does methotrexate work?

Need more info: Methrotrexate is used for many diseases. Please ask this question again and be specific about what the Methotrexate is being used for. ...Read more

9

9
For dose 6 of methotrexate for ctd, my dose is increased. I take on tues but concern w/ side effects & work.Okay to take 4 days early (sat from now on)? My rhemd said okay 2switch to a day that works.

For dose 6 of methotrexate for ctd, my dose is increased. I take on tues but concern w/ side effects & work.Okay to take 4 days early (sat from now on)? My rhemd said okay 2switch to a day that works.

Yes: It's okay to switch to Saturday. Remember not to do your blood tests on the same day as you take your methotrexate (MTX). The blood test monitoring for MTX is sometimes abnormal (but not significant) on the day or the day after taking MTX. ...Read more

See 2 more doctor answers
10

10
For juvenile arthritis is methotrexate safe?

For  juvenile arthritis is  methotrexate  safe?

Very safe!: Although i frequently use other agents for jia, i frequently add mtx to the therapeutic mix. Considering that the dose should be lower, i still favor the subcutaneous route rather than oral. However, I have not had serious issues with mtx and children. Make sure they get supplemental folic acid! ...Read more

See 1 more doctor answer
Dr. Robert Lowe
329 doctors shared insights

Rheumatrex (Definition)

Rheumatrex ...Read more