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Doctor insights on: Methadone Benzodiazepines Interaction

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Dr. James Dukelow
109 doctors shared insights

Benzodiazepines Level (Definition)

Testing blood levels of benzodiazepines is not a routine or common clinical test. It is done by simply taking a blood sample and testing it in the lab. It is most commonly done in research studies. An example of clinical use would be when there is a discrepancy between the prescribed dosage and ...Read more


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I take methadone and I am wanting to start a 3 day trial of plexus slim. Will this cause any drug interactions?

Plexus Slim: I agree with dr. Ibrahim. The main weight-loss ingredients in the supplement appear to be chlorogenic acid (like in green tea), garcinia cambogia, fiber, chromium, and components of hoodia. Other parts are sweeteners, flavorings, and antioxidants. This hasn't been tested in humans to see whether it interacts with medications (including methadone). It's ~$80/month after your 3 day "trial.". ...Read more

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What are the drug interactions between methadone and azithromycin ?

What are the drug interactions between methadone and azithromycin  ?

Arrthymia: There is a caution in combining the two medications due to the risk of qt prolongation resulting in an arrhythmia. ...Read more

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What would be symptoms ofa bad reaction to methadone or interaction of it with cipro (ciprofloxacin) or cymbalta or sudafed?

What would be symptoms ofa bad reaction to methadone or interaction of it with cipro (ciprofloxacin) or cymbalta or sudafed?

Methadone interactio: Cipro (ciprofloxacin) and Methadone together cause problems with cardiac arrhythmias prolonging what's called the qt interval. If you're on this combination then monitoring with an ekg would be a good idea. Cipro (ciprofloxacin) can increase Cymbalta levels. If you are already having side effects from the cymbalta, these will increase. Cymbalta and Methadone together can very rarely cause serotonin syndrome. I would recommend the google that so you know what the symptoms are. There's not enough space here to allow me to write those all out. Best wishes. ...Read more

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What to do if I am taking methadone I want to stop its been 2 years 105 ml a day .is ther anything I can take for withdrawal s?

TAPER THE METHADONE: If you stop cold turkey, you are going to feel like you have been hit by a truck for many weeks and even months. You will also very likely relapse to your drug of choice again after feeling that withdrawal day after day. The best way is to taper, ideally over at least a 90 day period. There are medications like clonidine that your doctor can prescribe, and you can treat the pain/diarrhea/nausea. ...Read more

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! hve been on 120 methadone maintenance for 16 yrs. I have weaned myself down to 50 n past 2 months . what dosage will be safe to just stop taking it?

Any dose: Withdrawal from methadone is safe for a reasonably healthy (and non pregnant) person from any dose. Having said that, you would be more comfortable continuing to taper slowly to about 5 or 10mg , then stopping. ...Read more

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How did i fail my drug test for methadone n benzos even when i haven't taken them?

How did i fail my drug test for methadone n benzos even when i haven't taken them?

Long half life: Certain benzo such as Klonopin (clonazepam) and valium have longer half life and stay in your body longer which is why they are detected a few days later, Methadone has the same property. ...Read more

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I am on methadone i can't sleep n I've gained , 50 lbs in two months n I have hives on ankles what is going on?

Go see your doctor: Methadone is used either to manage chronic pain or to treat heroin addiction. You didn't mention which but regardless, you need to see your prescribing doc. Methadone & other narcotics should be sedating rather than stimulating. Weight gain can be due to under active thyroid while insomnia can be due to over active thyroid. That's why you need to see your family doc who knows you to run right test. ...Read more

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Dr. Stuart Wasser
638 doctors shared insights

Methadone (Definition)

Methadone is a synthetic opiate used for pain control and in the rehabilitation of opiate addicts. Methadone used in rehabilitation relieves craving, suppresses withdrawal symptoms, and blocks the euphoric effects associated with ...Read more


Benzodiazepine (Definition)

They are used for anxiety ...Read more