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Doctor insights on: Methacholine Challenge

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Can a person fake a methacholine challenge?

Can a person fake a methacholine challenge?

It's hard: An experienced physician, pulmonologist, allergist, etc. Is able to tell when patients are not putting enough effort into a test. ...Read more

Dr. M. Hytham Beck
40 doctors shared insights

Provocholine (Definition)

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How can i prepare to pass a methacholine challenge?

Methacholin: Challenge is used if the diagnosis of asthma is in question. There is nothing to do to prepare to pass the test.you need to follow your doctors instructions exactly and stop any medications as directed. This is a potentially dangerous test and should only be done in a pulmonary function lab or in a doctors office with those trained to treat acute bronchospasm. It is better in ruling out asthma. ...Read more

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How long will the methacholine challenge usually take?

How long will the methacholine challenge usually take?

Less than 1hr: Less than 1 hr. 30min is about average, depending on how efficient the staff performing the test is in setting up each step, etc. It also depends on whether you have a positive result early vs towards to the end of the test. ...Read more

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How long until you get results of the methacholine challenge test?

Same day...: ... If your doctor is available when performing the test. They should be able to tell you immediately the results. ...Read more

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How long does it take to get results of the methacholine challenge test?

Methacholine test: The test result is available as soon as the test is completed. It can take half to one hour. A physician has to interpret the test results. Some times the answer may not be clear cut. ...Read more

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What factors could produce a negative methacholine challenge. Detail Please?

Maybe not asthma: A 19 yo with a negative methacholine challenge. A methacholine challenge test is ordered when a diagnosis of asthma is suspected but cannot be proven by history or in-office simple spirometry. A negative test usually means there is not a diagnosis of asthma. Please see your physician to determine exactly what is going on. ...Read more

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Are people still doing the methacholine challenge, and are there risks to it?

Are people still doing the methacholine challenge, and are there risks to it?

Methacholine test: Mostly it is done where the diagnosis of asthma is doubtful. It should be done under the careful supervisision of a physician who has experience in the bronchial challenge tests. The test can be done in the hospital pulmonary lab or in the office setting with appropriate. Staff and safety equipment to treat asthma like symptoms. The test is still being done when indicated. ...Read more

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What medication effects a methacholine challenge causing false negatives? In detail please?

What medication effects a methacholine challenge causing false negatives? In detail please?

There's a list of...: Things that may lead to a false negative: inhaled and oral bronchodilators, cromolyn, nedocromil, hydroxyzine, cetirizine, leukotriene modifiers, coffee, tea, cola drinks, and chocolate. Sometimes oral or inhaled corticosteroids are included in the list. Whether or not these things "cause" a negative depends on many factors. The list and more information is from the Cleveland Clinic website. ...Read more

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What are the risks doing the methacholine challenge?

Asthma diagnosing: This test is indicated when the diagnosis of asthma is in question (eg, symptoms are atypical, baseline testing is normal). There are contraindications to test such as pregnancy, recent heart attack and severe asthma. Also there are medicines, such as bronchodilators and steroids that must be stopped before the test is done to make it valid. Risks include severe asthmatic attack or heart attack. ...Read more

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Will Budesonide effect a methacholine challenge?

Medications: Yes it can by reducing inflammation and treating your asthma, bronchial responsiveness may be effected. Please consult with your PFT lab technician regarding which medications will need to be stopped prior to testing. ...Read more

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Will singulair (montelukast) significantly effect a methacholine challenge test?

Will singulair (montelukast) significantly effect a methacholine  challenge test?

Yes it will: Before doing Methacholine Chalenge test you are adviced to stop taking long acting Bronchodilaters,Allergy Meds Steroids and Singular as it may affect the test Singular needs to be stopped at least 24 hour before your test It can significantly affect the test ...Read more

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Would taking allegra (fexofenadine) before a methacholine challenge effect the results?

Would taking allegra (fexofenadine) before a methacholine challenge effect the results?

It can: You should obviously avoid asthma inhalers. The longer the work, the longer you should stop them for (eg advair for 24hrs). Antihistamines may not have as big an impact on the test as inhalers, but they should also be avoided for 24-48hrs. ...Read more

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Why do doctors tell you not smoke or to use caffeine before a methacholine challenge test?

Why do doctors tell you not smoke or to use caffeine before a methacholine challenge test?

For unaltered result: Since both caffeine (which can relax the bronchial muscle tone) and smoking - (which can irritate bronchial muscle tone making it more sensitive) - can affect the test - these factors and others are to be avoided ahead of a methacholine test which is trying to guage the patient's baseline bronchial reactivity (often to investigate the presence of asthma). ...Read more

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Why do doctors tell you not smoke or to use caffine before the methacholine challenge test?

Why do doctors tell you not smoke or to use caffine before the methacholine challenge test?

For unaltered result: Since both caffeine (which can relax the bronchial muscle tone) and smoking - (which can irritate bronchial muscle tone making it more sensitive) - can affect the test - these factors and others are to be avoided ahead of a methacholine test which is trying to guage the patient's baseline bronchial reactivity (often to investigate the presence of asthma). ...Read more

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I had the methacholine challenge test and it triggered bronchospasm on the lowest dose. What does this mean? Should i be on bronchodialators? I'm 27.

I had the methacholine challenge test and it triggered bronchospasm on the lowest dose. What does this mean? Should i be on bronchodialators? I'm 27.

Probably: It means you may have reactive airways disease. There are many inhaled drugs that can treat this, and published guidelines. Talk with your doctor about any further testing and follow his/her advice. ...Read more

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Asthma methacholine challenge. Is there side-effects from the test?

Asthma methacholine challenge. Is there side-effects from the test?

No...: If a patient is given methacholine and it results in bronchospasm, the patient is then given a bronchodilator which reverses the effect of the methacholine. ...Read more

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Will Dulera (formoterol and mometasone) significantly affect a methacholine challenge?

Yes: Should meds be stopped before a methacholine challenge? Yes. A methacholine challenge is used to diagnose asthma. Dulera (formoterol and mometasone) is a combination medication with a long-acting beta agonist and a steroid. Long-acting beta agonists should be stopped prior to testing for accurate results. Speak with your doctor to find out exactly how long you need to be off prior to testing (usually 2 days). ...Read more

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What are the chances of dulera (formoterol and mometasone) cause a negative methacholine challenge?

Very high: In fact, we ask our patients to avoid using Dulera (formoterol and mometasone) for at least 2 weeks before doing any methacholine challenge. In research settings however, methacholine challenge may be used to assess the effectiveness of Dulera (formoterol and mometasone). ...Read more

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Dr. Abraham Jaskiel
52 doctors shared insights

Methacholine (Definition)

Methacholine is an asthma agent which is a ...Read more