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Doctor insights on: Metformin Cause Megaloblastic Anemia

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Does metformin cause megaloblastic anemia?

Does metformin cause megaloblastic anemia?

It can: Megaloblastic anemia is caused by a deficiency in vitamin B12 or folic acid. Taking metformin can cause your body to "use up" vitamin b12, and become deficient in b12, which, in severe cases, could lead to megaloblastic anemia. This can usually be corrected with a vitamin B12 pill, unless there is also a problem with absorbing b12. ...Read more

Dr. David Sneid
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That reduces liver production of glucose- other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk ...Read more


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How follic acid deficiency causes megaloblastic anemia?

How follic acid deficiency causes megaloblastic anemia?

It just does :): Hello-
your body needs Folic Acid to make red blood cells properly. If you do not have enough it compromises the process. The body will not be able to produce red blood cells as well (anemia) and they will be bigger than normal red blood cells (megaloblastic = big). Thankfully some Folic Acid replacement should fix the problem quite easily. ...Read more

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How vit cyanoCObalamine deficiency causes megaloblastic anemia?

How vit cyanoCObalamine deficiency causes megaloblastic anemia?

B12: You need this vitamin to synthesize DNA (T's from U's). If you can't do this, the nuclear growth can't keep up with the cytoplasm and the red cells end up bigger before they can be released. Hence "megalo-". ...Read more

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Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more

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Are there supplements for megaloblastic anemia?

Are there supplements for megaloblastic anemia?

Cause can be treated: The cause of megaloblastic anemia has to be determined. If it is due to vitamin B12 or Folic Acid deficiency, supplements can help. Many people with B12 deficiency cannot absorb B12 orally and may need to have it injected. ...Read more

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What is the relationship between megaloblastic anemia and nourishment?

Megaloblastic anemia: Megaloblastic anemia is macrocytic anemia (elevated mcv/large rbc) that results fron inhibition of dna synthesis in RBC production. This can be caused by deficiency in vit b12, folate (folic acid) or drug induced. If you are a strict vegan- you are at risk to have vit B12 deficiency-thus you should take vit B12 supplement. Check and discuss further in detail with your doctor. ...Read more

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What differences are there in megaloblastic anemia and pernicious anemia?

Pernicious = Vit B12: Megaloblastic anemia refers to any condition which causes large red blood cells (folate (folic acid) deficiency, vitamin B12 deficiency, etc.) pernicious anemia can be thought of as a *type* of megaloblastic anemia which is caused by vitamin B12 deficiency secondary to malabsorption. ...Read more

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What is the difference between pernicious anemia and megaloblastic anemia?

Big RBC: Pernicious anemia is deficiency of vitaminb12 due to autoimmune attack on cell of the stomach and antibody against intrinsic factor- presented with megaloblastic anemia. Pa is only one of the causes of megaloblastic anemia- however other causes that can cause def vitb12, or folate (folic acid) or other drug eg. Bactrim- that inhibits dna synthesis in RBC production also can cause megaloblastic anemia. ...Read more

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What is a megaloblastic anemia?

Big red blood cell: Is a type of anemia presented with big size of red blood cells- that results from inhibition of dna synthesis during red blood cell production. This leads to continuing cell growth without division. It is most often due to hypovitaminosis, specifically a deficiency of vitamin B12 and/or folic acid, deficiency in micronutrient- as well as others including drugs/chemo etc. Work up needs to be done. ...Read more

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Is megaloblastic anemia an inherited condition?

Is megaloblastic anemia an inherited condition?

Not commonly: Most cases of this condition reflect deficiencies of key vitamins (b12, folic acid) and occur due to dietary deficiencies, pregnancy, pernicious anemia, medications. Rare inherited forms can occur in which the carrier proteins for B12 may be low for example. ...Read more

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Is there a connection between megaloblastic anemia and nutrition?

Is there a connection between megaloblastic anemia and nutrition?

Maybe: The common causes of megaloblastic anemia are vitamin B12 deficiency and Folic Acid deficiency. A diet poor in these vitamins may lead to megaloblastic anemia. ...Read more

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What's megaloblastic anemia?

What's megaloblastic anemia?

Anemia: Megaloblastic anemia is anemia related most commonly to vitamin B12 and Folic Acid deficiency. These problems are easily treated with replacement of the deficient vitamin. There are other much rarer causes of megaloblastic anemia, and other illnesses that may look similar to megaloblastic anemia. ...Read more

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What is the difference between megaloblastic anemia and regular anemia?

What is the difference between megaloblastic anemia and regular anemia?

Cause: Megaloblastic anemia is caused by vitamin B12 or Folic Acid deficiency, or rarely from other causes. In the blood, the red blood cells are large. In the bone marrow, there is delayed maturation of the red blood cell precursors that give a characteristic appearance when stained and looked at under the microscope. There is no "regular anemia". ...Read more

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Megaloblastic anemia can lead to some neurological disorders?

Megaloblastic anemia can lead to some neurological disorders?

Yes: Megaloblastic anemia is most commonly caused by vitamin B12 or Folic Acid deficiency. Neurologic symptoms might include weakness, numbness, difficulty walking and with balance. ...Read more

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Can you tell me is folic acid defiency anemia and megaloblastic anemia the same thing?

Can you tell me is folic acid defiency anemia and megaloblastic anemia the same thing?

Partially: Folic acid or folate (folic acid) deficiency is one of the causes of megaloblastic anemia but there are others including vitamin B12 deficiency, myelodysplastic syndromes, other blood cancers, genetic disorders, etc. ...Read more

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Does chewing ice cause anemia?

Does chewing ice cause anemia?

What you are.....: Describing is pagophagia, the consumption of ice in the setting of anemia, usually due to an fe deficiency state. The ice consumption is not causative, but rather emblematic. You should see your dr and be evaluated for fe deficiency. You may find that your dr checks your hematocrit and red cell indices, and if microcytic hypochromic anemia is detected, starts you on fe rx (cheaper than fe testing). ...Read more

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Can chewing on ice chips cause anemia?

No: There is an old wive's tale that chewing ice is a sign that someone may be anemic. But there is no way that chewing ice can actually cause anemia. ...Read more

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Can metformin HCl 500 cause coughing?

Can metformin HCl 500 cause coughing?

Unusual: Most of the side effects of metformin are stomach, gastrointestinal related, not cough. ...Read more

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Extreme anemia for a 60 yr. Old woman -causes?

Extreme anemia for a 60 yr. Old woman -causes?

Blood loss: Blood loss from the gastro intestinal tract is the most common cause. This could be due to gastritis, ulcer, hemorrhoids, diverticuli, or tumor. Nutritional deficiencies can lead to anemia as well. Cancer of the blood is another concern. Seek medical attention promptly. ...Read more

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Could metformin cause a loss of taste and smell?

Could metformin cause a loss of taste and smell?

Usually not: Tell your doctor you are having this problem. Acidosis, hypoglycemia and allergic reaction can occur. ...Read more

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Is it possible that hemochromatosis can cause anemia?

Is it possible that hemochromatosis can cause anemia?

Probably not: Hemochromatosis is caused by the accumulation of excess iron in the body - eventually depositing in the liver, heart and other organs. Anemia is not a typical sign, although a few rare types of anemia (thalassemia, for example) have caused secondary hemochromatosis. ...Read more

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Anemia can cause leukemia? I have anemia what should I do?

No: Anemia does not cause leukemia. Anemia is seen in lots of conditions. One of the most common is iron deficiency or nutritional. Anemia can be seen with leukemia but anemia does not cause leukemia. ...Read more

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Does poor sleep cause anemia?

Does poor sleep cause anemia?

No: It does not cause this directly, but whatever is causing the anemia can cause poor sleep. ...Read more

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Can anemia cause shoulder pain?

Can anemia cause shoulder pain?

Anemia and pain: Anemia can be caused by multiple underlying pathologies (ie. Iron deficiency, vit B12 deficiency, lead poisoning, chronic disease, blood cell dysfunction, sickle cell...). Some of these can lead to painful joints. If you have anemia the best thing to do is to find the source of it. You should also have your doctor perform a shoulder physical exam to rule-out internal pathologies. Hope that helps! ...Read more

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Does anemia cause high venous co2?

Most likely no...: Although this is a complex issue where several factors contribute. Co2 generation is a function of aerobic metabolism and decarboxylation of tca cycle intermediates. Significant anemia reduces o2 delivery to tissues and increases reliance on anaerobic metabolism --> tissue acidosis. A metabolic acidosis leads to respiratory compensation (which lowers blood co2). Whole books written about this. ...Read more

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What causes anemia even when on iron tablets?

What causes anemia even when on iron tablets?

Many: Iron only help if you are iron deficient, but anemia can be due to many reasons, you need to see your doctor for a full work up. Also note it takes more rhan a week to start improving if you just started iron., and your problem is iron def, also depends on if you are taking the right dose, normal absorbtion etc, also it is very important to find out why you are low in iron if that the real proble. ...Read more

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