Doctor insights on:
Metastatic Renal Cell Carcinoma Life Expectancy
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Often very good: It depends on the tumor stage, which is based on the tumor size and whether it is confined to the kidney or invades other structures. Many papillary renal cell carcinomas are small and confined to kidney, in which case they often do not recur. ...Read more
My brother has been diagnosed with metastatic renal cell carcinoma stage 4. Am I at risk of this disease. Is this cancer rare?
My brother has metastatic renal cell carcinoma and it's spread the doctor said he could pass anytime y r they still giving him chemotherapy?
So sorry: Once cancer metastasizes, it is no longer curable. However, individuals can live for some time especially if they are being treated by chemo or targeted therapies. I don't know your brother's exact situation nor dx. If treatment is too toxic for him, he can elect to stop. Drs may be giving him palliative tx which can help with pain and other symptoms. When time comes, consider hospice to help all. ...Read more
I had nephrectomy in feb. After that I was diagnosed as metastatic renal cell carcinoma (lung cancer). But I don't have any symptoms as doc said. Why?
Congratulations: Renal cell carcinoma is notoriously capricious and unpredictable. It's common for a lung metastasis to vanish or stay stable for many years, especially after removal fo the primary tumor. I'm going to assume the diagnosis is accurate. Cherish being alive and be thankful for whatever time you have left -- fill it with love and good things. ...Read more
Unusual but possible: Metastasis (spread) to the skin is uncommon for renal cell carcinoma. Lung is a much moe common site of spread. However, skin metastasis has been described. In fact, there are patients who were originally diagnosed solely through the biopsy of a suspicious skin lesion. Fortunately, unusual skin lesions are often accessible for biopsy which should decrease the uncertainty of diagnosis. ...Read more
Poor: Unfortunately even with chemo, stage IV renal cell has a short survival time. Some reasonably good chemo agents are coming available but present therapies may work for a while, then quit working. ...Read more
Many facilities: There are many academic facilities that treat renal cell carcinoma. These include, ucsf, usc, city of hope, and ucla. ...Read more
Maybe: How long has it been since your tumor was removed? 5 year survival for stage 3 tumor would be 67%. Grade of the tumor is also a factor. At 5 years, 93% of recurrences which will occur have occurred. Your oncologist will suggest the appropriate surveillance strategy. Best of luck to you. ...Read more
How long does renal cell carcinoma take to spread? Been 3 months since found. Authorization taking awhile. Labs say hasn't spread to other parts yet.
Not clear cut:
There is no special test that is an early sensitive indicator. The current guidelines after removal of a kidney tumor is exam, ldh and other blood test and ct scan.
In many tumors we have found that routine testing is not a great help.
A key idea is that any symptoms that is new or worrisome should be investigated quickly. Target the test to the symptom. ...Read more
Most likely Stage I: All tumors are staged by the tumor, nodes, metastasis (staging system). Stage I kidney tumors are less than 7 CM in size and have no evidence of lymph node as well as distant metastasis. Stage ii tumors are larger than 7 CM and have no lymph node or distant metastasis. Stage iii tumors are locally advanced. Stage IV tumors have spread to lymph nodes or other organs. ...Read more
Varies with stage: Fortunately many renal cell carcinomas are now being diagnosed at an early stage (when the tumor is small and doesn't invade any other structures) thanks to improvements in imaging (ct scan etc). If early stage, many patients do very well after the tumor is removed. However, as the stage of the tumor increases, the risk of the cancer behaving aggressively increases. So stage helps to predict. ...Read more
Varies: Even within stage 4, there are varying severities of disease. Survival can occasionally go beyond five years though most people will succumb in two or less years. ...Read more
? egfr??: Please avoid using abbreviations...they may have different meaning to different folks. Is this epidermal growth factor receptor (EGFR) that you are talking about? Or is this something related to GFR (glomerular filtration rate) which is a test for Kidney function??? . Please clarify so that we can address your question properly. ...Read more
It depends: I know that's what we always say. But stage 4 renal cancer prognosis depends on many factors. Someone who is very ill with an elevated ldh, elevated calcium, and anemia has months to a year. Someone who responded to immunotherapy and has normal labs may have several years or more. Your doctor knows, and if he/she is not saying, ask. And say you want the truth. ...Read more
Please: Consult your urologist or the md who diagnosed the disease. Blindly my advise would be if you have a medical school in your proximity, even if many miles away, I would make an appointment with them immediately. Do not neglect the problem every day should count! ...Read more
Is polycythemia the cause of renal cell carcinoma or renalcell carcinoma the cause of polycythemia?
Polycythemia: Polycythemia is not the cause of renal cell carcinoma. ...Read more
Increased risk.: Smoking introduces many very carcinogenic compounds into the bloodstream, which is filtered by the kidney. These carcinogens, along with the decreased tissue oxygenation caused by smoking, is theorized to increase the risk of renal cell carcinoma. A meta-analysis of 24 studies (hunt, int j cancer 114:101-108, 2005) showed this significantly increased risk, & it is considered causal by the ussg. ...Read more
What are the chances of metastatic renal cell cancer in a nephrectomised patient with clear cell carcinoma (fuhrman grade 2)?
Need more info: Stage and grade are needed to estimate this risk. One can check nomograms dot org where a number of such risk calculators can be accessed. ...Read more
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