Doctor insights on:
Metastatic Papillary Adenocarcinoma
Several things.: In this sentence metastatic most likely means the disease has spread to other organs such as liver, lung, etc. And would be considered stage 4; alternatively it could mean spread to lymph nodes only and would represent stage 3 disease. Signet ring is a description of what the cell looks like. Adenocarcinoma is the type of tumor and can arise from the GI tract, prostate, lung, breast or stomach. ...Read more
Metastatic tumor: The treatment of metastatic adenocarcinoma depends on the nature of the primary, the site of metastasis and the degree of metastatic tumor. Pancreatic Ca with one lesion in the liver is unresectable and treated by chemo such as Gemzar (gemcitabine) Abraxane. Colon Ca with one lesion to liver is resected. When any met is unresectable chemo is always used alone or in combination with RT. ...Read more
Subtype of colon Ca: Mucin producing metastatic adenoca of the colon is derived from a primary adenoCa of colon producing large amounts of extracelluar mucin with greater than a 50% mucinous component. The proximal colon and appendix represents 10-20% of these colorectal neoplasms. The rt. Colon is the usual source for most of these lesions presenting with more advanced forms of disease than other colonic sites. ...Read more
My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive, stage 4. She started folfox. Can it be cured? Life expectancy?
Serious diagnosis: Stage 4 colon cancer has a very poor prognosis. No one can give you a life expectancy that is exact. It depends upon her response to the treatment. Some people respond very well. Of all people that have this diagnosis only about 8% of them are still alive at 5 years. But still she could be one of that 8%. I hope she responds well to the treatments. ...Read more
Regional spread: Many tumors, as they evolve, develop the potential to spread. The lesions develop matrix metalloproteinase which forms small e-cadherin from the cell cement and allows for spread. Regional nodes are a common site and for lesions on the arm and chest, spread is to the axilla. Lt. breast carcinomas as they grow and spread frequently are noted in the left axillary lymph nodes as metastatic adenoca ...Read more
My mother has been diagnosed with metastatic adenocarcinoma with mucinous features. Can you explain what this means?
Glandular activity: Primary tumors with mucinous features are those that are derived from organs producing mucin to allow the organ to function. The most common organ whose tumor, an adenocarcinoma, has mucinous features is that from colon. As such the metastatic tumors would have segmental areas within the spreading lesion that demonstrates the presence of fields of mucin on histologic exam. ...Read more
What do you suggest if my mother has been diagnosed with metastatic adenocarcinoma with mucinous features. What does this mean?
Many things: Adenocarcinoma means a cancer derived of epithelial cells of glandular origin (not from a gland necessarily). Metastatic means that it has spread. Mucinous features means that the pathologist saw areas of mucin outside the cells, the significance of this depends on how much and where. It being metastatic is probably the most important thing prognostically, but please discuss with oncologist. ...Read more
My mom (50 yrs) was detected with papillary adenocarcinoma of ovary. Endometrium, cervix were normal. Please suggest me the better way to proceed?
My fil, 68 yrs, biopsy report stating "well differentiated papillary adenocarcinoma" @ rectosigmoid junction. Dr suggests surgery -R we doing right?
What is TTF-1, Napsin and CK7 mean in lung biopsy mean? Can papillary adenocarcinoma spread by blood if no nodes involve?
Arcana: These are special stains used by the pathologist to determine exactly what kind of lung cancer we're dealing with. No result means anything in isolation. Any lung cancer can spread by blood, and even clean lymph nodes does not mean the cancer will not recur. Estimating the odds of length of curvival / possibility of cure is based on many variables. Good luck. ...Read more
My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive stage 4 cancer. She's on folfox. Life expectancy??
Varies from months/y: The overall survival of stage 4 colon cancer varies from 1 to 3 years. Most patients have at least 2 years if their tumor responds to chemo. If you tumors regresses after chemo, it may even be surgically removable in which case long term survival (even a cure) can be possible. Ask more questions to your treating oncologist. ...Read more
Hello, Please let me know what is the reason for occur metastatic lymph node cancer??? 2nd Question : Is Adenocarcinoma is called tumor??? What happen
Yes it is a cancer: Adenocarcinoma is one type of common Cancer which can arise from any gland forming organ such as Breast, Colon and lung. If left untreated for a long time, cancer cells spread and can involve regional lymph nodes and later spread to the internal organs. I hope you are under the care of a cancer specialist (Oncologist) who can guide you further and offer the required treatments. ...Read more
What is the prognosis for nsclc with pleural extension in stage 1b pT2aN0 adenocarcinoma grade 2 Papillary predominant 80%, 20% acinar aft lobectomy. See pathology report in my file. No treatment after lobectomy? I am still exceedingly fatigued.
Cancer: The best person to give you an answer to this question is the treating physician. Good Luck ...Read more
Hi, I was asked to do rai for my metastatic papillary carcinoma (i had a tt)a year &10 months ago. I never had my rai. Do u think my cancer spread a lot?
Need information: 22 months after total thyroidectmy for papillary adenocarcinoma of thyroid y you have rai scan or rai treatment? , you have to give more information, even if you have lymph node metastasis had rai treatment, at 81 yr old, will not be as serious as it sounds, these are relatively very slow growing tumors, don't worry you will be fine, speak to your doctor for more assurance, . ...Read more
Several factors: Amount of rai dose is caliculated, based on several factors, age, sex, body weight, extent of disease, blood levels reaching less than bone marrow toxic dose of lees than 200 rad. Dose varies li greater than 1.10 (30mci) most of the doctors will not bother to know as the expert radiotherapists doctors who are specially trained will calculate and administer ri. ...Read more
Had tt a year and 3 months ago for metastatic papillary thyroid cancer. I haven't had rai. On the average did the cancer spread to other organs?
Thyroid: Papillary metastasizes outside the neck only about 10-15% of patients while local lymph nodes nay occur in up to 50% of patients. You should get rai if you are otherwise healthy. ...Read more
Will there be an uptake for i-131 during rai if there was no uptake for i-123 pre-scan for metastatic papillary thyroid cancer?
I had metastatic papillary thyroid cancer and never had rai after total thyrodectomy. I wanna take it soon. Was it bad I didn't do the rai right away?
Lucky: You may simply be a lucky person--not everyone needs to have rai, particularly those with small tumors. Discuss it with your surgeon and/or endocrinologist. If you do indeed need it, don't worry--there is still time. ...Read more
Can metastatic papillary thyroid cancer spread to the parathyroid? Is this rare? Can recurrent pap thyroid cancer show up on parathyroid?
Parathyroid: Presumably you have had surgery followed by radioactive iodine. This could damage the parathyroid and cause hypoparathyroidism, although this usually does not happen. Thyroid cancer spreads locally (within the neck), and that could damage the parathyroids more, but again, this does not usually happen. Check this out with your endocrinologist. ...Read more
Hx of late stage metastatic papillary thy cancer. Can thy cancer spread to the liver? Poss mass found on no contrast CT which I read is a bad sign.
Does rai normally eradicate the cancer cells in metastatic sites of papillary thyroid carcinoma? Or does it only reduce the tumors in these sites?
Eradicate: Rai can eradicate thyroid cancer cells from distant sites such as the lung or bone. It may not be completely effective with everyone, however, as some tumor cells at these distant sites have lost the ability to take up the iodine like normal thyroid cells can. In such cases, repeat and/or higher doses may be required. ...Read more