Doctor insights on:
Metastatic Lymph Node Cancer
Depends: Lymph nodes are one aspect of evaluation for stage and treatment of breast cancer. It depends on size of breast cancer itself, number of lymph nodes involved, hormone status of the tumor, and dna testing can also help identify breast cancer risks. If the lymph node involvement is small, then there is little additioanl risk to the patient. There are many factors involved in assessing breast cancer. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Regional spread: Many tumors, as they evolve, develop the potential to spread. The lesions develop matrix metalloproteinase which forms small e-cadherin from the cell cement and allows for spread. Regional nodes are a common site and for lesions on the arm and chest, spread is to the axilla. Lt. breast carcinomas as they grow and spread frequently are noted in the left axillary lymph nodes as metastatic adenoca ...Read more
Not neccessarily: Ultrasonography itself cannot distinguish benign from malignant lesions, but an echographic appearance suggests malignancy and helps in the selection of the node to aspirate with ultrasonographically guided fnab, which is crucial for a final diagnosis. You need to have the node sampled with a needle to know if it is benign or otherwise. Talk to your physician. ...Read more
No: A lymph node replaced with malignant cells growing as a primary lymphod tumor or metastatic from another site which has spread to axilla will not shrink without treatment, either chemo or RT. The node will enlarge further or if unchanged will spread to adjacent nodes. It does not have the potential to metastasize further to non lymphatic tissue such as liver or lung. ...Read moreSee 2 more doctor answers
Could cancer metastase to distant regional lymph nodes before it metastase to the nearby lymph nodes?
No: tumors metastasize to regional nodes before distant nodes, but what goes to nodal disease only stays nodal. When breast spreads to nodes, one pos. axillary node is said to have better prognosis that 10 nodes. This is not due to # nodes but more nodes means primary has been spreading over a longer period of time. If axilla speads it is only to supraclavicular nodes and no other site. ...Read more
Monitoring Centers: Lymphatic system absorbs/carries things too big to go into the arteries/veins like bacteria eaten by white cells and digested food. Lymph nodes "taste" the lymph for anything bad like bacteria/viruses/cancers, etc. When it detects a problem, it alerts the immune system and your body reacts. They enlarge in response to the inflammation they create when they react. They shrink when all is well. ...Read moreSee 1 more doctor answer
Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read moreSee 3 more doctor answers
No: A schmorl's node is basically a weakness in the endplate of a vertebra through which disc material is displaced into the vertebral body. The term "node" is misleading and has nothing to do with cancer. Schmorl's nodes are very common, usually asymptomatic but can be a source of pain if they are acute. ...Read moreSee 1 more doctor answer
That depends on: what you mean. Hodgkins lymphoma or non- Hodgkins lymphoma start in lymph system. If there is cancer found in a lymph node (& not a lymphatic cancer) then it is metastatic from where it originated. But having a painful or swollen lymph doesn't automatically mean that there is cancer in that particular node. It needs to be tested to know. ...Read moreSee 1 more doctor answer
CTshows Spleen 17cm ,small Axillary Lymph nodes, retroperitoneal lymph nodes& mesentric lymph node noted, normal blood count &bone marrow,no infection?
Many possibilities: The combination of enlarged spleen and internal lymph nodes could be any of several infections (mononucleosis, syphilis, HIV, and several others, of course depeding on risk); inflammatory conditions like sarcoidosis; various malignancies like lymphoma and others. The doctor(s) who have been evaluating this problem and requested the CT scan are the only ones who can answer accurately. Good luck. ...Read more
Many rt. Paratracheal/mediastinal, bilateral hilar nodes consistent w/metastasis. Right subcarinal metastatic node mass 3cm. Max suv 9.1. Lung cancer?
Needs Biopsy: Is there a known primary cancer? If not, you will need a biopsy of one of the nodes. Your doctor may suggest a mediastinoscopy and biopsy to get a tissue specimen. There are other causes of mediastinal node enlargement such as infection and sarcoidosis so it is important to make a definite diagnosis. Good luck. ...Read moreSee 3 more doctor answers
Unclear question: Lymphoma is a tumor (often malignant) of the lymphatic cells and there are different types (i.e., hodgkin's, non-hd, etc.). These can present with non-tender enlarged lymph nodes, along with other signs and symptoms. Some lymphomas are curable and some treatable and controllable for long time periods. ...Read more
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