Doctor insights on:
Metastatic Infiltrating Ductal Carcinoma
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. The type of cancer (ductal, lobular, etc) doesn't impact survival. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read moreSee 1 more doctor answer
Send us UR? in Engli: Sorry I can not read Spanish. But if you have Invasive ductal carcinoma...that means cancer. If it is not invasive(it is called Ductal carcinoma in situ) that is a pre-cancer. Go see a surgeon and ask for advice for further treatment as you will likely need surgery to remove either one of the two conditions that I have mentioned. ...Read more
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Highly Variable: The risk of breast cancer growing outside of the breast is most dependent on the aggressiveness of the cancer and the stage at diagnosis; it is less related to the type of breast cancer (ductal, lobular, etc). While metastatic disease may be present at the time of diagnosis, a majority of breast cancer patients never develop metastases. ...Read moreSee 2 more doctor answers
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
Cancer 'elsewhere': Metastatic cancer is cancer that has spread from its organ of origin to another part of the body. For example, the most common sites of metastases for breast cancer are the lungs, liver, and bone. Most breast cancers, when caught early and treated in a timely manner, do not ever spread to other organs. ...Read moreSee 1 more doctor answer
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
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- Alternative treatments for infiltrating ductal carcinoma
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