Doctor insights on:
Metastatic Colon Cancer Liver Prognosis
Can high increasing bilirubin in metastic colon cancer with liver mets cause death ? What is prognosis ?other LFT "s are normal
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Yes, it can be an op: This pill is often used in Japan. So it is not popular in the US. Moreover, it is better to be treated with a combination of 2 or 3 medicines that are proven useful in the treatment of metastatic colon Cancer. I would advise you to seek a second opinion so that you can make sure that your treatment is not substandard. ...Read more
What kills a person in metastic colon cancer . Does the liver have to fail or can the mets alone cause death ?
Many ways: The actual mechanism varies. The liver or the cancer itself can get infected. Even small lung metastasis can cause pneumonia, or the overall debility from the cancer can cause this. Deep thrombi are one of several more common ways. Biliary obstruction is more common than actual liver failure. Bowel obstruction can hopefully be prevented by your surgeon. ...Read moreSee 2 more doctor answers
Metastic colon cancer with liver mets . Bilirubin was 12, then went to 95 and now 85.
Is it starting to drop again ?
ALT reading -50
ALP reading -140
Is this suggestive of liver failing
Metastic colon cancer ?
Liver function: The enzymes (ALP & ALT) are indicative of only mild liver dysfunction. The rising bili suggests that some degree of bile obstruction may be occurring. This could be due to the mechanical obstruction of small ducts by metastatic disease. But the liver has a large degree of reserve capacity, so full liver failure is unlikely to be final cause of death even with very bulky mets. ...Read moreSee 1 more doctor answer
Will avastin increase survival significantly for metastic colon cancer with liver mets ?
Is it a risky drug
Slight benefit: Bevacizumab (Avastin) is one of those drugs that is extremely expensive and often has limited benefit. Patients with metastatic colon cancer who received Avastin plus chemotherapy lived 1-2 months longer on average than those receiving chemo only. Because it has marginal benefit but costs ~$30,000 the U.K. Health Service won't pay for it. It can cause skin rash, bleeding or wound healing problems. ...Read more
No: A CAT scan is used to visually define the extent of metastatic colon cancer in the liver should metastasis be present. Liver failure is a condition measured by functional abnormalities that occur within the liver usually due to parenchymal damage such as inflammation from hepatitis . Here one measures serum enzymes and the presence of elevated alkaline phosphatase and bilirubin in serum. ...Read moreSee 1 more doctor answer
Metastic colon cancer . Ct scan showed disease stable after 3 chemo rounds . Largest liver met 8 cm. bilirubin was 12,19,12,33,51,now 74. What can this be ?
Hyperbili: If jaundiced, intrahepatic (liver caused) levels of bilirubin are likely here. One cause is hepatitis, possibly from chemo, or from the met. In some cases, high bilirubin in adults may be caused by blockages in the bile ducts, depending on where the met is. Symptoms include digestive distress and pain in the abdomen, hard to distinguish from chemo caused side effects. Talk to your cancer doctor. ...Read moreSee 1 more doctor answer
If chemotherapy treatment fails for metastic colon cancer pt, what else can be done for a liver met, 1 node and a tiny lung nodule ?
Remove lung lesion: At age 34 attempt at cure should be made. If liver met small and primary already out, liver met to be resected or microwave ablated. Usually chemo is only of temporary value and if all fails, the FDA protocol for monoclonal antibody Neo102 is available for treatment of metastatic colon cancer having failed chemo. the small node and lung lesion can be removed by laparoscopy/thoracoscopy. ...Read more
Metastic colon cancer .... On chemo , after 3 round scan shows increase in liver and peri mets and no increase in a aortocaval node . Size not known. What can this mean ?
Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more
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