Doctor insights on:
Metastasis Vs Metastases
Different lesions: A sarcoma is a malignant lesion arising from connective and not glandular tissue such as visceral leiomyosarcoma of uterus or stomach. metastatic disease represents spread of tumor that may arise from a sarcoma or carcinoma, lymphoma is a malignant form of blood cellular disease and paraganglioma is the benign form of the lesion arising from nerve tissue. All represent different forms of disease. ...Read more
A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more
Pancoast tumor: Occurs at the top of the lung and invades out and up to involve muscles, nerves, and thereby causing pain and horner's syndrome. Metastasis usually means going to another organ. If confined to chest and outward extension (?Metastasis), outlook is more optimistic. If it metastasized to brain, lung, liver or distant bones, the outlook is bleak, seek symptom management, there is no cure. ...Read moreSee 1 more doctor answer
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more
Many rt. Paratracheal/mediastinal, bilateral hilar nodes consistent w/metastasis. Right subcarinal metastatic node mass 3cm. Max suv 9.1. Lung cancer?
Needs Biopsy: Is there a known primary cancer? If not, you will need a biopsy of one of the nodes. Your doctor may suggest a mediastinoscopy and biopsy to get a tissue specimen. There are other causes of mediastinal node enlargement such as infection and sarcoidosis so it is important to make a definite diagnosis. Good luck. ...Read moreSee 3 more doctor answers
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read moreSee 3 more doctor answers
Prostate cancer: This is an advanced stage of prostate cancer; the good news is there are many new drugs and treatments for men in this stage that have been shown to extend life; in this stage survival is extremely variable from months to years isn't impossible. ...Read moreSee 1 more doctor answer
Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read moreSee 1 more doctor answer
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?
Highly Variable: The risk of breast cancer growing outside of the breast is most dependent on the aggressiveness of the cancer and the stage at diagnosis; it is less related to the type of breast cancer (ductal, lobular, etc). While metastatic disease may be present at the time of diagnosis, a majority of breast cancer patients never develop metastases. ...Read moreSee 2 more doctor answers
Depends: Lymph nodes are one aspect of evaluation for stage and treatment of breast cancer. It depends on size of breast cancer itself, number of lymph nodes involved, hormone status of the tumor, and dna testing can also help identify breast cancer risks. If the lymph node involvement is small, then there is little additioanl risk to the patient. There are many factors involved in assessing breast cancer. ...Read more
Prostate cancer: The most common metastatic site would be bones-although it also can go to other sites- lymph glands, lung, liver etc.. Symptoms will depend on the location of metastases. Bone pain, fractures would be the symptoms of bony mets. If spread to the adjacent area such as bladder area- blood in urine, lower abdomen pain, prob wi/ urination, obstruction can happen. Weight loss, weakness are common too. ...Read moreSee 1 more doctor answer
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read moreSee 1 more doctor answer
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more