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Metanephrines Random Urine
Stopped going to old doc but just got labs back from 8mos ago. Random urine metanephrine/creatinine was .5 mcg/mg crt. No ref range provided. Normal?
Call the lab: You should be able to call the lab to get the reference range. Interpretation of the results will not be done by the lab. If you get a new doctor, be sure to share the results with them. Hope this helps! ...Read more
Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more
Often no: The plasma has more sensitive and more specific and generally adequate (better) in most situations. It would depend if the doctor is more worried about a false positive (finding pheochromcystoma you really don't have), or more worried about false negative (missing the disease when you really have it). Your doctor would decide based on your symptoms which is the bigger worry /risk. ...Read moreSee 1 more doctor answer
What does it mean if my Metanephrines Total (244) and Nor/Epinephrines Totals (107) are Elevated in my urine? I just got an email from the lab that ran these tests.
Warrants followup: Most common reason urine metanephrines & catecholamines are checked is suspicion for pheochromocytoma, a rare adrenal gland tumor. For high levels not in pheo range (=norepi >170mcg/day epi >35/day,metanephrine>400/day), suspicion depends on risks; followup w doc is important.Some folks have higher levels normally, or are on meds interfering(TCAs, decongestants, amphetamines, antipsychotics,other) ...Read more
My metanephrine free urine was 51, blood test was 63, normetanephrine free urine 181, blood test 150- total urine 232, blood test 213. Normal?
Sounds normal if....: the upper limits for blood metanephrine and normetanephrine are 0.50nm/l and 0.90nm/l. Urinary levels are, respectively: Total 24 hr. metanephrine =1.3mg for urine; and total plasma ME+NME is less than 205pg/ml. It sound as though you're within the normal ranges, but depending on the units of measure, which vary from lab to lab and med ctr to med ctr., you may not. Meet w/ your endocrinologist. ...Read more
If normethanephrine free 181pg/ml & metanephrine free 232 pg/ml 24hr urine collection, will my sister's matanephrine fractionated blood work be bad?
What are the advantages of the plasma free metanephrine blood test over the standard urine tests for pheochromocytoma?
More senditve& speci: By about 20percent.Get a more detailed answer ›
Should i redo 24 hrs urine test for catecholamines metanephrine if i had a cigarette or just give it to lab?
My metanephrine free was 232pg/ml suggestive of a pheochromocytoma(1) suggested I rpt the 24hr urine & serum chromogranin A for confirmation. Normal?
Phenol vs ether: The chemical structure of epinephrine, the natural hormone generated in excess by a pheochromocytoma tumor, has an aromatic carbon ring with two adjacent -oh (phenol) groups and a side-chain amino group. Compounds with this structure are called catecholamines. Metanephrine is a metabolite of this hormone, with one phenol converted to an ether (-och3). If elevated, it implies the tumor. ...Read moreSee 1 more doctor answer
Normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your result seems to be normal. You may consult this site for more info on this topic. https://medlineplus.gov/ency/article/003613.htm ...Read more
Free metanephrine 64, total plasma metanephrine 301 and normetanephrine 237. 3 weeks post total thyroidectomy. Anything to worry about?
Laboratory normals: Your question cannot be answered unless we know the following: 1. What laboratory did the tests and what are their normal reference ranges. 2. Did you take any medications that could interfere with the assays? 3. Did you have any foods that might interfere with the assays? Also, why were these tests done? If you are looking for a pheochromocytoma, they might help. Otherwise, probably not. ...Read more
BP related hormones: Metanephrines are hormone compounds related to the presence of an endocrine tumor called a pheochromacytoma. These tumors cause hypertension, the metanephrines are elevated in the blood and urine and mark the presence of the tumor. This test should lead to further localization of the tumor and possible removal. ...Read more
Metabolic product: Metanephrins are metabolic products of cathecolamines: epinephrin and norepinephrin and can be used to diagnose excess production of these adrenal/sympathetic hormones. They can be measured in blood and urine and are very elevated in a condition called pheochromocytoma which is a tumor found mostly in the adrenal glands that causes severe hypertension. ...Read moreSee 1 more doctor answer
Metanephrine: You should discontinue Epinephrine and epinephrine-like drugs for at least 1 week before the test, stop using Acetaminophen 48 hours beforehand, and fast for 8-10 hours prior to collection. It is especially important not to have any caffeine containing food (soda, chocolate), coffee (including decaf), tobacco (smoking cigarettes or cigars), tea, or alcohol for at least 4 hours before specimen coll. ...Read moreSee 1 more doctor answer
Metanephrins are metabolic products of cathecolamines: epinephrin and norepinephrin and can be used to diagnose excess production of these adrenal/sympathetic hormones. They can be measured in blood and urine and are very elevated in a condition called pheochromocytoma which is a tumor found mostly in the adrenal glands ...Read more
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