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Metanephrines Random Urine
Stopped going to old doc but just got labs back from 8mos ago. Random urine metanephrine/creatinine was .5 mcg/mg crt. No ref range provided. Normal?
Call the lab: You should be able to call the lab to get the reference range. Interpretation of the results will not be done by the lab. If you get a new doctor, be sure to share the results with them. Hope this helps! ...Read more
Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more
Often no: The plasma has more sensitive and more specific and generally adequate (better) in most situations. It would depend if the doctor is more worried about a false positive (finding pheochromcystoma you really don't have), or more worried about false negative (missing the disease when you really have it). Your doctor would decide based on your symptoms which is the bigger worry /risk. ...Read moreSee 1 more doctor answer
What does it mean if my Metanephrines Total (244) and Nor/Epinephrines Totals (107) are Elevated in my urine? I just got an email from the lab that ran these tests.
Warrants followup: Most common reason urine metanephrines & catecholamines are checked is suspicion for pheochromocytoma, a rare adrenal gland tumor. For high levels not in pheo range (=norepi >170mcg/day epi >35/day,metanephrine>400/day), suspicion depends on risks; followup w doc is important.Some folks have higher levels normally, or are on meds interfering(TCAs, decongestants, amphetamines, antipsychotics,other) ...Read more
What are the advantages of the plasma free metanephrine blood test over the standard urine tests for pheochromocytoma?
More senditve& speci: By about 20percent.Get a more detailed answer ›
Should i redo 24 hrs urine test for catecholamines metanephrine if i had a cigarette or just give it to lab?
Phenol vs ether: The chemical structure of epinephrine, the natural hormone generated in excess by a pheochromocytoma tumor, has an aromatic carbon ring with two adjacent -oh (phenol) groups and a side-chain amino group. Compounds with this structure are called catecholamines. Metanephrine is a metabolite of this hormone, with one phenol converted to an ether (-och3). If elevated, it implies the tumor. ...Read moreSee 1 more doctor answer
Metanephrins are metabolic products of cathecolamines: epinephrin and norepinephrin and can be used to diagnose excess production of these adrenal/sympathetic hormones. They can be measured in blood and urine and are very elevated in a condition called pheochromocytoma which is a tumor found mostly in the adrenal glands ...Read more
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