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Doctor insights on: Metabolites Of Valium

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Dr. Amrita Dosanjh
511 doctors shared insights

Valium (Definition)

Valium (diazepam) is an older benzodiazepine tranquilizer. It was the #1 prescribed drug (of any kind) in the us in the late 1960s but is used less now due to drug interactions and active metabolites. It is still used for anxiety and as "pre-medication" for uncomfortable medical and minor surgical procedures. It is habit-forming, should not be used with alcohol, ...Read more


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6mgs of ativan (lorazepam) equals how many mgs of clonazepam?

6mgs of ativan (lorazepam) equals how  many mgs of clonazepam?

Hard to say: Since it depends if we are talking about acutely, where it takes twice as much Clonazepam to equal the clinical effects of lorazepam. However, once Clonazepam reaches it's steady state, it is actually twice a potent as lorazepam. So, initially you might need 3 mg of Clonazepam four times a day for the first day to feel the same effects, but you quickly have to reduce down to 1 mg three time/d. ...Read more

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Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?

Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?

Valium tolerance: When valium induces tolerance, this includes all its cns-depressant effects. It's similar to alcohol, where someone could appear "sober" despite having a high blood alcohol level. If the blood alcohol level dips from usual, withdrawal symptoms may be experienced. ...Read more

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Can ativan (lorazepam) increase the effects of tramadol?

Can ativan (lorazepam) increase the effects of tramadol?

Probably: Tramadol is used for pain relief and has less addiction risks than narcotics. Pain can cause anxiety and vise versa. I believe that ativan, (lorazepam) a benzodiazepine that decreases anxiety, can increase effects of tramadol. Reisk of abuse increase though! ...Read more

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Can Valium and clonazepam show same drug in drug screen?

Can Valium and clonazepam show same drug in drug screen?

Same class of drugs: Klonipin is stronger than valium but both are classified as benzodiazepins. It depends on how detailed the test is but i think that most who do drug tests would be looking for the type of drug and not the specific brand. ...Read more

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Which drug stays in your system longer, ativan or xanax (alprazolam)?

Benzodiazepines & UA: They are literally the same chemicals. If you need to pass a ua they may be in the system up to six weeks. Benzodiazepines stay around a very long time. ...Read more

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How long is ativan (lorazepam) detectable in a urine drug screen?

How long is ativan (lorazepam) detectable in a urine drug screen?

Less than a week: Typically this drug is not detectable by the urine drug screen after 4 to 5 days. It depends on the condition of your liver and if other drugs are present and competing for metabolism. It also depends on the sensitivity and specificity of the test itself. Hope this helps! ...Read more

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Are clonazepam, lorazepam, triazolam the same drug?

Are clonazepam, lorazepam, triazolam the same drug?

Not same group: All are sedatives but are different; clonazepam (klonopin) is long-acting benzodiazepine for anxiety @12 hours). Lorazepam (ativan) is short-acting benzodiazepine for anxiety (4-6 hours). Triazolam (halcion) is hypnotic for insomnia & is short-acting. ...Read more

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Tips on detoxing from high dose of ativan (lorazepam)?

Tips on detoxing from high dose of ativan (lorazepam)?

Medical attention.: Detoxing from hisgh dose of Ativan (lorazepam) need to be done slowly and under close supervision of your physician, to prevent benzo withdrawl seizure. ...Read more

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How does klonopin (clonazepam) differ from Ativan in its intended effects, length of action, dosing frequency?

How does klonopin (clonazepam) differ from Ativan in its intended effects, length of action, dosing frequency?

Both have similar: uses, anxiety, panic etc. The ativan has a 14 hour half life and klonopin (clonazepam) 20-50 hour half life both are used 2-3 times daily. Ativan being shorter acting will tend to be more addictive but both drugs have a high addiction potential. ...Read more

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How come of the seizure medicines; depakote, tegretol and klonopin (clonazepam) -why is klonopin (clonazepam) only known for withdrawls?

How come of the seizure medicines; depakote, tegretol and klonopin (clonazepam) -why is klonopin (clonazepam) only known for withdrawls?

See below;: It is important to note that discontinuing any of those medications abruptly puts a person with epilepsy at risk of increased seizure frequency. The same is only true for clonazepam in a person *without* epilepsy, and therein lies your answer: clonazepam works differently than the other two and is associated with withdrawal disorders, like alcohol and certain drugs. ...Read more

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What's the mgs for 0.25 Xanax (alprazolam) and half of another Xanax (alprazolam) ?

What's the mgs for 0.25 Xanax (alprazolam) and half of another Xanax (alprazolam) ?

Xanax (alprazolam) dose?: Do you mean how much is 1and ½ of a Xanax (alprazolam) 0.25 mg pill? It's 0.375 mg of Xanax (alprazolam). ...Read more

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Is a 1mg tablet of ativan (lorazepam) stronger than a 25mg pill of librium?

Is a 1mg tablet of ativan (lorazepam) stronger than a 25mg pill of librium?

Probably not: While the benzodiazepine equivalence chart I have indicates 1mg of Ativan (lorazepam) to be equivalent to 10-25 mg, a 2009 study did a head to head comparison in treating alcohol withdrawal with the two drugs. That study found the two medications to be equally effective and the authors compared starting doses of 8 mg/day of Lorazepam to 80 mg/day of librium, as such i would tend to lean to the 10/1 ratio. ...Read more

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Which benzo is harsher on your liver--klonopin or Ativan (lorazepam)?

Which benzo is harsher on your liver--klonopin or Ativan (lorazepam)?

Clonazepam: Benzodiazepines are rarely associated with elevated liver functions or clinically apparent liver injury and have not caused acute or chronic liver failure. However, there have been a few case reports about Clonazepam irritating the liver [none about Ativan] and therefore it would be considered slightly harsher.Their effect on the liver is probably due to a rarely produced intermediate metabolite. ...Read more

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Is Xanax (alprazolam) different from valium?

Xanax (alprazolam): Xanax (alprazolam) is shorter-acting benzo. More potent for panic attacks than valium. Both are addicting & tolerance develops with continued use. ...Read more