Doctor insights on:
Metabolites Of Valium
Valium (diazepam) is an older benzodiazepine tranquilizer. It was the #1 prescribed drug (of any kind) in the us in the late 1960s but is used less now due to drug interactions and active metabolites. It is still used for anxiety and as "pre-medication" for uncomfortable medical and minor surgical procedures. It is habit-forming, should not be used with alcohol, ...Read more
Hard to say: Since it depends if we are talking about acutely, where it takes twice as much Clonazepam to equal the clinical effects of lorazepam. However, once Clonazepam reaches it's steady state, it is actually twice a potent as lorazepam. So, initially you might need 3 mg of Clonazepam four times a day for the first day to feel the same effects, but you quickly have to reduce down to 1 mg three time/d. ...Read more
Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?
Probably: Tramadol is used for pain relief and has less addiction risks than narcotics. Pain can cause anxiety and vise versa. I believe that ativan, (lorazepam) a benzodiazepine that decreases anxiety, can increase effects of tramadol. Reisk of abuse increase though! ...Read moreSee 1 more doctor answer
Less than a week: Typically this drug is not detectable by the urine drug screen after 4 to 5 days. It depends on the condition of your liver and if other drugs are present and competing for metabolism. It also depends on the sensitivity and specificity of the test itself. Hope this helps! ...Read moreSee 2 more doctor answers
Not same group: All are sedatives but are different; clonazepam (klonopin) is long-acting benzodiazepine for anxiety @12 hours). Lorazepam (ativan) is short-acting benzodiazepine for anxiety (4-6 hours). Triazolam (halcion) is hypnotic for insomnia & is short-acting. ...Read moreSee 1 more doctor answer
Depression: Slows functions down.Get a more detailed answer ›
How does klonopin (clonazepam) differ from Ativan in its intended effects, length of action, dosing frequency?
How come of the seizure medicines; depakote, tegretol and klonopin (clonazepam) -why is klonopin (clonazepam) only known for withdrawls?
See below;: It is important to note that discontinuing any of those medications abruptly puts a person with epilepsy at risk of increased seizure frequency. The same is only true for clonazepam in a person *without* epilepsy, and therein lies your answer: clonazepam works differently than the other two and is associated with withdrawal disorders, like alcohol and certain drugs. ...Read moreSee 1 more doctor answer
I took .5 klonopin (clonazepam) 2x daily w/tegretol..klonopin (clonazepam) ineffective..does tegretol reduce the length of time klonopin (clonazepam) works-8hrs or it strength?
Probably not: While the benzodiazepine equivalence chart I have indicates 1mg of Ativan (lorazepam) to be equivalent to 10-25 mg, a 2009 study did a head to head comparison in treating alcohol withdrawal with the two drugs. That study found the two medications to be equally effective and the authors compared starting doses of 8 mg/day of Lorazepam to 80 mg/day of librium, as such i would tend to lean to the 10/1 ratio. ...Read more
Clonazepam: Benzodiazepines are rarely associated with elevated liver functions or clinically apparent liver injury and have not caused acute or chronic liver failure. However, there have been a few case reports about Clonazepam irritating the liver [none about Ativan] and therefore it would be considered slightly harsher.Their effect on the liver is probably due to a rarely produced intermediate metabolite. ...Read moreSee 1 more doctor answer