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Doctor insights on: Metabolism Of Folate

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Factors affecting absorption, metabolism and excretion of digoxin?

Factors affecting absorption, metabolism and excretion of digoxin?

Renal: This medication is cleared by the kidneys do when renal function worsens digoxin levels increase. ...Read more

Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


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Effect of acid secretion on absorption of iron and vitamin b12?

Effect of acid secretion on absorption of iron and vitamin b12?

Acid has a profound: Effect on iron. Acid is better. Not an issue with b12, as the issue is intrinsic factor from the stomach which is a cofactor in B12 absorption. ...Read more

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Does folate (folic acid) deficiency affect brain's health of the baby ?

Does folate (folic acid) deficiency affect brain's health of the baby ?

See below: Folate (folic acid) deficiency can affect the development of the brain and spinal cord of the fetus. ...Read more

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Will high amounts of magnesium supplements block absorption of folic acid?

Will high amounts of magnesium supplements block absorption of folic acid?

Unlikely: well high dose of anything is bad. Therapeutic dose of magnesium should not do that as b Vitamins including folic acid are needed in magnesium metabolism. Too much magnesium causes diarrhea so it is conceivable that there can be nutritional malabsorption including folic acid ...Read more

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What is the importance of b vitamins in glucose metabolism?

What is the importance of b vitamins in glucose metabolism?

Energy metabolism: They are essential items in the complex process of producing cellular energy. Since the body is made up of trillions of cells that cooperate together to create function, the energy that drives that function is a necessity ...Read more

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Does folate (folic acid) deficiency anemia affect the brain and nerves?

Does folate (folic acid) deficiency anemia affect the brain and nerves?

Yes: Folate (folic acid) is needed for maintenance and repair of myelin, the covering of larger/faster nerve fibers. Deficiency in utero results in birth defects of the neural cord, low birth weight or prematurity. Deficiency will slow growth in children. Peripheral neuropathy results in adults. Deficiency is reversible if treated early enough. Nerves suffer from folate (folic acid) deficiency itself more than from anemia. ...Read more

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Is a Serum level of Copper of 61 µg/dL and an RBC level of 49 µg/dL of Copper low enough to interfere with Iron absorption and metabolism?

Is a Serum level of Copper of 61 µg/dL and an RBC level of 49 µg/dL of Copper low enough to interfere with Iron absorption and metabolism?

Follow up needed: In order to accurately interpret these labs results, one has to be sure of the normal ranges used by the lab. These results also need to be correlated with your overall health status Going by the info above, it appears like you've been seen by someone who ordered these labs, I will strongly recommend following up with him/her for further evaluation. ...Read more

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Will 2000mg of nicotonic acid increase liver enzymes?

Will 2000mg of nicotonic acid increase liver enzymes?

Yes, but: Nicotinic acid which is niacin (Vitamin B3) can cause brief elevations in liver enzymes in some people which can resolve and pose no problem in most. Here is a detailed discussion on the subject: http://livertox.nih.gov/Niacin.htm ...Read more

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Is ascorbic acid involved in synthesis of andrenaline?

Is ascorbic acid involved in synthesis of andrenaline?

Ascorbic acid: is an essential nutrient, but not involved directly in synthesis of adrenaline. Ascorbic acid intake does not affect adrenaline levels. ...Read more

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What is the pathway and role of vitamin B12 in metabolism/catabolism of phenylalanine and tyrosine? Thank you.

What is the pathway and role of vitamin B12 in metabolism/catabolism of phenylalanine and tyrosine? Thank you.

Nothing: In the normal child less than 50% of dietary phenylalanine is utilized for polypeptide ; protein synthesis. Most of that remaining is converted to tyrosine. All this takes place by enzymatic chemical activity and I am not aware that vitamin b-12 is involved. ...Read more

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What are symptoms of being folate (folic acid) deficient?

What are symptoms of being folate (folic acid) deficient?

Folic Acid: A Folic Acid deficiency can present with fatigue, oral ulcerations, tongue swelling, graying hair and inadequate growth. ...Read more

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Does magnesium supplements block the absorption of folic acid?

Does magnesium supplements block the absorption of folic acid?

No: Not to the best of my knowledge. Various b vitamins like b-complex is needed for optimal magnesium function ...Read more

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What micromineral deficiency can interfere with vitamin a metabolism by reducing retinol binding protein?

What micromineral deficiency can interfere with vitamin a metabolism by reducing retinol binding protein?

Carotene and others: Many proteins, and enzymes are involved in vitamin a metabolism. Some proteins are involved in creating the useful form of vitamin a into 11-cis-retina from vitamin a or b-carotene, which is useful in vision. Some proteins transport vitamin a , such as retinol binding protein. Many nutrients important such as zinc, lipids, carotenes. Age related eye study vitamins: ww.Areds2.Org. ...Read more

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Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Not likely: Please consult this site for info in this topic. Folate (folic acid) and B12 are needed for efficient red cell production and other functions, but lack of one does not increase the other. http://www.webmd.com/diet/folic-acid. ...Read more

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Are folate and folic acid the same thing?

Folate /folic acid: Yes the two words are used interchangeably. ...Read more

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Does oxcarbazepine increase the metabolism of methadone?

Does oxcarbazepine increase the metabolism of methadone?

Maybe: Interaction checker indicates this may increase or decrease methadone levels. This is not a good combination of medications. Only use if prescribed and closely monitored. ...Read more

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What kind of supplement has activated folate (folic acid) and is typically recommended over Folic Acid suppliments?

What kind of supplement has activated folate (folic acid) and is typically recommended over Folic Acid suppliments?

Green leafy plants: I'm more of an advocate of getting your vitamins from FOOD, not from a bottle - where the substances within have been processed. Folate (or folic acid) is found naturally in green leafy plants - the name actually derives from 'foliage' or 'leaves'. So I advocate eating fresh veggies/plants. That type of diet also provides different minerals, micronutrients, anti-oxidants, fiber etc. that you need. ...Read more

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Which people are at high risk for folate (folic acid) deficiency?

Usually poor diet: Typically poor diet in green leafy vegetables can do it. Also patients on the strict atkins with no supplements can get that. But it is difficult with a health diet. ...Read more

Dr. Kristi Woods
668 doctors shared insights

Folate (Definition)

Folate is a vitamin which is a kind of nutritional agent ...Read more