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Doctor insights on: Metabolic Acidosis

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Dr. Fred McCurdy
60 doctors shared insights

Metabolic Acidosis (Overview)

Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally any loss of bicarb (diarrhea etc).


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How does metabolic acidosis affect liver clearance of drugs? I.E. Should i stop my medications during metabolic acidosis

How does metabolic acidosis affect liver clearance of drugs? I.E. Should i stop my medications during metabolic acidosis

See below.: Patients with acidosis severe enough to affect drug metabolism are usually in the ICU with bigger problems. Mild degrees of acidosis are probably not sufficient to affect the clearance of many medications. ...Read more

Dr. Fred McCurdy
60 doctors shared insights

Metabolic Acidosis (Overview)

Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally any loss of bicarb (diarrhea etc).


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What symptoms characterize metabolic acidosis?

What symptoms characterize metabolic acidosis?

See below: Metabolic acidosis can be detected by blood teasts. Patients can present with kussmauls breathing which is deep ventilation or breathing. Some patients have abdominal pain blood tests show a low bicarbonate (sodium bicarbonate) level and a low co2 level seen on blood gases.This is a serious condition with many causes, commonly seen with diabetic ketoacidosis. ...Read more

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What are the tests for metabolic acidosis?

See below: Metabolic acidosis can be detected by blood teasts. Patients can present with kussmauls breathing which is deep ventilation or breathing. Some patients have abdominal pain blood tests show a low bicarbonate (sodium bicarbonate) level and a low co2 level seen on blood gases.This is a serious condition with many causes, commonly seen with diabetic ketoacidosis. ...Read more

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Can topamax (topiramate) cause metabolic acidosis?

Can topamax (topiramate) cause metabolic acidosis?

Yes: Among the side effects, including cognitive issues, narrow angle glaucoma, heat stroke risk in kids, kidney stones; is also, metabolic acidosis, which can potentially be life threatening. It has been associated with kidney disease, and surgery. It is advised to stop topamax (topiramate) if surgery is planned. ...Read more

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What does this mean "high anion gap metabolic acidosis"?

What does this mean "high anion gap metabolic acidosis"?

Anion gap: The anion gap is a calculation in which you subtract the sum of the negative ions in the blood (chloride, bicarbonate) from the sum of the positive ions (sodium, potassium). Often potassium is left out because it has only a very small effect. A normal gap is < 11. If the result of the subtraction is > 11 you have a high anion gap acidosis, which means some other acid is causing acidosis (ketoacids. ...Read more

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What are ways to treat metabolic acidosis?

See below: Medications used to treat metabolic acidosis are sodium bicarbonate or citrate salts. Discuss doses and preparations with your doctor. ...Read more

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Need expert help here. What are some ways of treating metabolic acidosis?

Correct the problem: Metabolic acidosis from renal tubular disease is treated with bicarbonate, (sodium bicarbonate) lactic acidosis requires treating the source of the acid production, ketoacidosis requires relief of the diabetes or starvation with Insulin and carbohydrates. The source of the imbalance for acidosis must be identified and corrected. ...Read more

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What is the treatment for metabolic acidosis?

What is the treatment for metabolic acidosis?

Acidosis: The body compensates for metabolic acidosis by increasing the respiratory rate in order to alkalinize the blood by removing carbon dioxide. Acute treatment of metabolic acidosis requires administration of i've bicarbonate (sodium bicarbonate) or by performing urgent dialysis. ...Read more

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What are the tests for metabolic acidosis?

See below: Metabolic acidosis can be detected by blood teasts. Patients can present with kussmauls breathing which is deep ventilation or breathing. Some patients have abdominal pain blood tests show a low bicarbonate (sodium bicarbonate) level and a low co2 level seen on blood gases.This is a serious condition with many causes, commonly seen with diabetic ketoacidosis. ...Read more

Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more