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Doctor insights on: Mesalazine Raynauds

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Dr. Michael Miller
265 doctors shared insights

Raynaud's Disease (Definition)

Raynaud's disease is a disease of the small blood vessels. Triggers such as cold temperatures causes vasospasm of the blood vessels and thus decrease blood flow. Fingers classically turn white, then blue, then red ...Read more


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Can mesalazine be the cause of raynaud's syndrome?

Can mesalazine be the cause of raynaud's syndrome?

Unlikely: Mesalamine is not a likely culprit though it is not impossible. Meds like beta blockers are more likely causes. Autoimmune diseases are more likely causes for raynaud's. ...Read more

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Could mesalazine be responsible for causing raynaud's syndrome?

Could mesalazine be responsible for causing raynaud's syndrome?

Maybe not: Mesalazine (mesalamine, 5-asa) is the active ingredient of sulfasalazine. Mesalazine is for treating inflammatory bowel disease (ulcerative colitis, crohn's disease) and does not contain sulfa (avoids the problems of sulfa allergy or sulfonamide side effects). There was a report of raynaud's occurring with sulfasalazine, but I have not seen raynaud's reported with mesalazine. ...Read more

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How common is raynaud’s?

How common is raynaud’s?

3%-5% have symptoms: Raynaud's disease (no cause found) and raynaud's syndrome (caused by another medical condition) are not that rare. An estimated 3% to 5% of the population have raynaud's phenomenon, although symptoms can range from quite mild all the way to severe. ...Read more

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Where did the name raynaud’s come from?

French physician: The scleroderma foundation website states that in 1862, auguste-maurice raynaud, a french physician, wrote a thesis describing the color changes of hands and feet triggered by exposure to cold. Scleroderma is an autoimmune disorder (connective tissue disorder) in which patients can have raynaud's symptoms as part of their disease. ...Read more

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If raynaud’s is so common, how come i’ve never heard of it?

If raynaud’s is so common, how come i’ve never heard of it?

It's not in the news: Raynaud's disease (with no cause found) and raynaud's syndrome (caused by another medical condition) are not that rare. An estimated 3% to 5% of the population have raynaud's phenomenon, although symptoms can range from quite mild all the way to severe. People with mild symptoms learn to keep warm, and might not talk about their symptoms as a disease (to them, it may just be an annoyance). ...Read more

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Is there a cure that works for raynaud`s syndrome?

Is there a cure that works for raynaud`s syndrome?

Doubtful: Typically i would say there is no cure for raynauds. The one instance would be if smoking causes the symptoms of raynauds (which it can), and if you quit smoking it could go away. However, most patients with raynauds require treatment to reduce the symptoms of the condition. Avoiding direct contact with cold objects for example could reduce the symptoms. Medications can be quite helpful. ...Read more

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I’ve heard that there’s a surgical procedure to improve raynaud’s. What is it?

I’ve heard that there’s a surgical procedure to improve raynaud’s. What is it?

Sympathectomy: Thoracic sympathectomy is the procedure to cut the "sympathetic nerve" fibers coming out of the spine at the level of t2-t3 (second and third thoracic vertebrae). The nerve fibers usually cross over the second, third, & fourth ribs near the spine. Some doctors are using an endoscope to do this procedure, which would leave almost no surgical scar. The same procedure stops excessive hand sweating. ...Read more

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Is there a connection between trigger finger(s) and raynaud's condition?

Is there a connection between trigger finger(s) and raynaud's condition?

Usually not: Trigger finger is a problem with finger tendons and how they work to move a finger. Raynaud's phenomenon is a problem with spasm of arteries in the fingers, blocking blood flow. They are not directly related, but people with raynaud's syndrome can have connective tissue disorders, so may also have trigger finger. Overuse injuries, such as in certain jobs, can cause trigger finger and/or raynaud's. ...Read more

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Who gets raynaud’s?

Who gets raynaud’s?

Sometimes familial: Raynaud's symptoms sometimes run in families. People with a variety of disorders can get raynaud's phenomenon. Examples include: scleroderma, lupus, rheumatoid arthritis, sjogren's syndrome, atherosclerosis, subclavian aneurysm, beta-blocker drugs, ergotamine-type drugs, hypothyroidism, reflex sympathetic dystrophy, magnesium deficiency, etc... ...Read more

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