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Doctor insights on: Mesalamine Rectal Suspension Enema

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My biopsy result is chronic inflammation w/ lymphoid hyperplasia but my new GI insist its only IBS but my 1st GI prescrbed salofalk 4* aday. Confuse?

My biopsy result is chronic inflammation w/ lymphoid hyperplasia but my new GI insist its only IBS but my 1st GI prescrbed salofalk 4* aday. Confuse?

Probably IBS: I agree with that your G.I. Doctor that this may be irritable bowel syndrome and not also have colitis crohn's disease or other types of active colitis. Lymphoid hyperplasia is a very common condition in the colon and terminal ileum. Chronic inflammation is very nonspecific and when mild with out features of autoimmune disease is often a variant of normal. ...Read more

Enema (Definition)

An enema is the introduction of liquid into the rectum to evacuate the bowels[ principly the colon/ large ...Read more


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How much time am I suppost to hold in a mesalamine enema?

How much time am I suppost to hold in a mesalamine enema?

Ideally you should: Be able to hold it in through the night time sleep cycle. This may take several days before you can accomplish this. The longer you hold the more effective the treatment. Let your prescribing doctopr know if after a week you are still not able to go thru the night holding the enema ...Read more

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Using colocort enema every 3 days to control inflammation from colitis in addition to asacol (mesalamine) daily. Is long time usage of colocort bad? No problem yet

Using colocort enema every 3 days to control inflammation from colitis in addition to asacol (mesalamine) daily. Is long time usage of colocort bad? No problem yet

Maybe: Colocort is a steroid medication. Although you are using it in limited fashion and in a topical form, there is still systemic absorption and, over time, steroid side effects can occur (bone loss, glucose intolerance, hip problems, cataracts, etc). Best to discuss your concerns with your provider to see if Mesalamine enemas would help or if you need a different steroid sparing medication. ...Read more

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Doctor prescribed me mesalamine enema for hemorroids today. Will the enema or mesalamine suppositories work better?

Doctor prescribed me mesalamine enema for hemorroids today. Will the enema or mesalamine suppositories work better?

Not sure: mesalamine enemas are used for colitis that extends up to the second half the colon, while mesalamine suppositories are used for colitis of the rectum (proctitis). I do not use mesalamine for hemorrhoids. So you may want to double check on this with your doctor. ...Read more

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Suffer from rectal ulcer with sessile polyp, I have continuos bloody mucous bleeding with constipation, am on pentasa (mesalamine) what to do else?

Suffer from rectal ulcer with sessile polyp, I have continuos bloody mucous bleeding with constipation, am on pentasa (mesalamine) what to do else?

Rectal Ulcer: You are on Mesalamine for uc? Of course, the bleeding and mucus is likely associated with active ulcerative colitis. A large sessile polyp, if it is a true polyp and not a uc pseudo polyp, can secrete mucus itself. It sounds to me that your ulcerative colitis is still not under control. Having said that, the rectal ulcer is likely associated also with your active disease. Get a 2nd opinion. ...Read more

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I am on pentasa (mesalamine) and flagyle for rectal ulcer, is that effective and safe am breast feeding?

I am on pentasa (mesalamine) and flagyle for rectal ulcer, is that effective and safe am breast feeding?

Safe/ no problem: Both medications are considered relatively safe during breast feeding. I can't comment about the effectiveness of the treatment, not part of my area. ...Read more

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I am on pentasa (mesalamine) for rectal ulcer but I am breast feeding my 9 months old baby is that risky?

No: But Pentasa (mesalamine) is not a great treatment for a recital ulcer. Very little of the active Mesalamine found in oral Pentasa (mesalamine) will reach the rectum. It is usually reserved for those with small bowel involved crohn's. For a rectal ulcer, one should consider rectal treatment (enema or suppository) I would question your doctor. ...Read more

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Does pentasa (mesalamine) has any side effect during breast feeding cause I have rectal ulcer and breast fed my 7/12 old baby? Is it risky?

Does pentasa (mesalamine) has any side effect during breast feeding cause I have rectal ulcer and breast fed my 7/12 old baby? Is it risky?

Probably safe: While there are no large controlled studies of this medication during bf, the reported side efects are rare or minor. Watery diarrhea has been reported but that overlaps with expected bf stools anyway. See hale t "medications and mothers milk, 15ed, 2012. ...Read more

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I have rectal ulcer with rectal prolapse am taking pentasa (mesalamine) for 3 months but my doctor advise me to do pelvic floor exercises why? And how to do it?

I have rectal ulcer with rectal prolapse am taking pentasa (mesalamine) for 3 months but my doctor advise me to do pelvic floor exercises why? And how to do it?

Pelvic strengthen: You have rectal prolapse. Your doctor wants you to strengthen your supporting muscles so perhaps your prolapse will not recur. Ask your doctor for help and use your local library for pelvis exercise books. If it recurs you may need surgery. Try amazon books? Hope this helps. ...Read more

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Have UC. Switched 2 nites ago from 1g Mesalamine suppository to 4g Mes. Enema. Experiencing flu-like symps. Diarrhea, body aches and abd pain. Why?

Have UC. Switched 2 nites ago from 1g Mesalamine suppository to 4g Mes. Enema. Experiencing flu-like symps. Diarrhea, body aches and abd pain. Why?

Mesalamine: These symptoms are common adverse effects of this medication, and in your case, may be related to increasing the dosage. Best of health to you! ...Read more

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What are the possible consequences of taking 4, 000 mg of pentasa (mesalamine) everyday?

Usually helps: 4000 mg is the usual dose of Pentasa. The active ingredients in Pentasa is mesalamine. It is usually well-tolerated, and very often helps with inflammatory bowel conditions in the bowel. Lists of the rare possible side effects are easily found online. The important thing is to be sure that your IBD is not worsening after starting the medication. If it is, contact your doctor. ...Read more

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Will pepto interfere with asacol (mesalamine)?

Will pepto interfere with asacol (mesalamine)?

Unlikely: Pepto and Asacol (mesalamine), if taken together, should not cause any issues. You shouldn't need both together though ...Read more

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Does mesalamine cause stools to be black in color?

Does mesalamine cause stools to be black in color?

No: Mesalamine should not turn stool black. Black stool can be a sign of internal bleeding or a side-effect of consuming iron supplements or bismuth. ...Read more

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Does asacol (mesalamine) become toxic past its expiration date?

Uncertain: In general, it is recommended that medications not be used after expiration date. With that said, there is a big difference between being expired for 5 days versus 5 years. Your pharmacist should be able to provide more information. ...Read more