Doctor insights on:
Mepivacaine Leukotriene Inhibitor
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
No problem: These two medications should have no significant interactions. ...Read more
For the full list: would see your pharmacist.Get a more detailed answer ›
How can the therapeutic effects of antacid drugs, h2 blockers, proton pump inhibitor drugs, misoprostol?
Question?: I'm not sure I fully understand what your question is? The drugs you listed all help with symptoms of GERD or stomach ulcers, and they have different means by which they help patients with these problems. The safest and easiest to take are antacids and H2 blockers. Please consider rephrasing your question more specifically. ...Read more
Any interactions plaquenil methotrexate motrin800 Tylenol500 folic acid prilosec aspirin lopressor cartia imdur ambian singulair xyzal (levocetirizine) melatonin ?
Too many: You are taking so many drugs that it is difficult to tell whether drug interaction may occur. Even if you run a profile in Epocrates , it is impossible to tell whether a combination with another drug may lead to interaction. Thus you will require close monitoring by your doctor and be on the lookout for any adverse effects. ...Read more
I'm using 2 rotacaps for asthma (salbutamol sulphate& ipratropium bromide, fluticasino propionate& formaterol fumarate). Is the long term use safe?
Yes and no: The last drug you mentioned formaterol is a long acting beta agonist (laba). In the us, labas alone are used in treating copd. When used in asthma and to reduce their potential serious side effects, they must be combined with a steroid like fluticasone. ...Read moreSee 2 more doctor answers
Evidence says not: One meta-analysis* (a study pooling results from multiple other studies) suggested that reboxetine is ineffective & may be harmful. *(eyding d et.Al. "reboxetine for acute treatment of major depression: systematic review &meta-analysis of published &unpublished placebo &selective serotonin reuptake inhibitor controlled trials."bmj. 2010; 341:c4737). ...Read moreSee 1 more doctor answer
I'm immune to the hydromorphone actions, but not other opioids such as demerol (meperidine hydrochloride) (meperidine) or morphine?
Sounds confusing: In that hydromorphone is metabolized into morphine, and that is the effective agent in our bodies. There are people who may lack the enzymes to metabolize certain drugs, and this has been reported in some people with codeine, where the enzyme that metabolizes it to morphine is absent. It is possible you have something similar. Sometimes it is that you have not gotten the right dose by right route. ...Read more
About the same: Topical nasal steroids have about equal efficacy (activity) and safety. Flonase (fluticasone) and Nasonex (mometasone) are about the same. It depends on what your physician gets into the habit of using. Also some patients prefer one over the other because one of the two topical sprays is less irritating. There is little evidence that one is better than the other. ...Read more
What is the best local anestesic of choice when pregnant lidocaine (category b) or mepivacaine (cat c)?
See below: Depends. For an IV insertion Lidocaine is best. Fast onset and fast removal. For a spinal i would use bupivicaine for a spinal, and Lidocaine for an epidural. Talk to your anesthesiologist for their opinion. If you are talking about dental procedures the amount used is so small that it should not affect the fetus. ...Read moreSee 2 more doctor answers
Local anesthetics: Hexylcaine has a much shorter half life than mepivicaine. So, in a practical sense mepivicaine is more powerful. ...Read more
Drinking mepivacaine: First, your mouth will get very numb. Then you may anesthetize the muscles in your mouth and throat and thus feel like you are choking or gagging on your tonge and completely unable to swallow anything (or it may go into your lungs). So this is not a good idea at all. Otherwise, it is not poisonous by itself. ...Read more
Depending: On the quantity,and speed of injection a range from nervous system problems to seizures then cardiac to death ...Read more
It depends: It depends more on the size of the wound. You didn't provide enough information to answer directly. I usually need less than 10 mL for most of the lacerations I repair in my emergency department. ...Read more
Got ehlers danlos syndrome, tooth extraction, it wouldnt budge. Mepivacaine and still felt pain when drilling. Really don't want a general!
If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?
No: It is still one steroid injection. Biotransformation in liver is important for drugs given trough mouth, im and IV since those effect depend on concentration of drug in blood. Liver (and p450 enzyme system) has relatively little effect on drugs injected in joints, epidural space, tendons, body cavities. ...Read more
Pain med: Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys. Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker. ...Read moreSee 1 more doctor answer
Will cause severe BP: Tyramine in large doses can raise your blood pressure, that can cause a stroke and death. Small doses don't do that because there is enough MAO in your intestinal tract to metabolize the tyramine. When you take a MAO inhibitor, tyramine is no longer metabolized in the gut, so it is free to raise your blood pressure to a very high level. This is less likely to happen with topical MAO called emsam. ...Read more
Increase BP: Tyramine in large doses can raise your blood pressure, that can cause a stroke and death. Small doses don't do that because there is enough MAO in your intestinal tract to metabolize the tyramine. When you take a MAO inhibitor, tyramine is no longer metabolized in the gut, so it is free to raise your blood pressure to a very high level. This is less likely to happen with topical MAO called emsam. ...Read more
Few: Carbocaine is an amide local anesthetic. It's side effects are similar to any amide local anesthetic which can include allergic reactions, nerve injury, and toxicity if overdosed. Sign and symptoms of high levels include ringing in the ears, numbness of the lips, metallic taste in the mouth, confusion, loss of consciousness, heart arrhythmias, or cardiac arrest. ...Read more
Drug out of China: Huperzine a might have some benefit similar to drugs such as donepezil, rivastigmine, or galantamine, (galantamine hydrobromide) as it too, is a cholinesterase inhibitor. Has received hype in the alternative literature, due to lack of branding and commercial ownership, but it is unlikely to be any better than the above prescription meds. Do not waste money pursuing the "chinese aricept". ...Read more
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