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Doctor insights on: Meniscal Allograft Transplantation

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Is stem cell a procedure for me? I am 33 and have a damaged meniscus from a previous injury. I had a doctor tell me that i need a meniscal allograft.

Is stem cell a procedure for me? I am 33 and have a damaged meniscus from a previous injury. I had a doctor tell me that i need a meniscal allograft.

Stem cell: The terminology of "stem cell" use in the knee is being thrown around quite freely. A quasi "stem cell" approach is the platelet rich plasm (prp) injections that are gaining traction for osteoarthritis of the knee. Meniscal allograft has a limited indication in a "young" patient with joint pain, intact adjoining articular surfaces and previous total meniscectomy. ...Read more

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Dr. Neigatha Graney
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


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Nerve transplants possible in the next 10 years?

Nerve transplants possible in the next 10 years?

Nerve transplants: Yes quite possible. The biggest issue is coverage. Right now where we are heading is toward rationed care, expensive services will be restricted. If transplants are expensive and successful in less than 50% of cases they will likely not be covered. Pt will be needed after and this is already being restricted under obamacare to 24 sessions unless a new problem arises. ...Read more

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Please help! what is the most needed/requested organ for transplants?

Please help! what is the most needed/requested organ for transplants?

Kidneys: There nearly 100,000 patients with kidney failure who are waiting for donor kidneys; however, there are fewer than 10,000 deceased donor kidneys that become available every year. ...Read more

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I'm wondering if i donate my body for transplants, will it be frozen until completely utilized?

Organs don't freeze : Unfortunately, our organs don't freeze well so that we can thaw them out for use at a later time. We can cold preserve them at 4degs celsius and use them at a delayed time of up to ~48hrs for kidneys, 18hrs for livers, 16hrs for pancreas, and 6hrs for hearts with reasonable success. ...Read more

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How can organ transplants work?

Healthy new organ!: When your own organ(s) don't work they fail to perform the key functions that keep you alive. Replacement parts (from another human) are connected to you. Medications are given to prevent your immune system from recognizing that these "new" organs have different DNA than you do, preventing rejection. Technical success + consistent use of medications (every single day!) = success. ...Read more

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Why do some people need kidney transplants?

Why do some people need kidney transplants?

ESKD: Patients who end up with end-stage kidney diseases (ESKD) need kidney transplants. Common causes of ESKD in the U.S. include diabetes mellitus, hypertension, polycystic kidney diseases, glomerulonephritis, and toxins/medications. ...Read more

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Could you give me some info on organ transplants?

Broad topic: That's a broad topic. Many organs are transplantable. I refer to you the United Network of Organ Sharing (UNOS) at unos.org for more information. ...Read more

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Can you have bilateral nephrectomies without a transplant?

Yes: If both kidneys are removed the patient will have renal failure. In order to survive the patient will need renal replacement therapy with some form of dialysis treatment or a kidney transplant. ...Read more

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Are there any other options besides transplanting a kidney?

Are there any other options besides transplanting a kidney?

Dialysis: When the kidneys have failed entirely only dialysis and kidney transplantation are effective for treatment unless the kidneys recover function on their own or with treatment. There are several types of dialysis, but if a patient with irreversible kidney failure is a candidate for transplantation, that is almost always the best therapy for a longer lifespan and better quality of life. ...Read more

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What medications would a transplant recipient have to take?

Meds : Transplantation has become widely available only because we have developed effective immunosuppressive medications that help prevent rejection. These medications put the patient at risk for opportunistic infections , so prophylactic antibiotics and antiviral agents are commonly used with them. Additionally, whatever medications the patient needs for other health issues (htn, dm, hyperchol...). ...Read more

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Can a person have multiple kidney transplants in their life?

Can a person have multiple kidney transplants in their life?

Yes: There are many people who receive their second kidney transplants during their lifetime. I am aware of a couple of patients who received a total of four renal transplants in their lifetimes. ...Read more

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Can you tell me how is technology helping organ transplants?

Developments: Developments in all fields of transplant are quiet significant....many in the fields of immunosuppressive agent developments, trials and their clinical introduction....for example the kidney survival in three years in mid 80s was 50%....now low 90s.....no ideal immunosuppressive available....meaning none are selective or specific and there are great deal of intra and interinsividual variabilities ...Read more

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Can the organs from people who have oded be used for transplant?

Perhaps: Some individuals that become brain dead after a drug over dose can become organ donors. If the organs in question are functioning, they can be removed. However, there may be increased risk for the transfer of infections such as hepatitis b and c, and HIV that are often associated with illicit drug use. Careful testing for these infections and informed consent from the recipient is needed. ...Read more

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What technology is used in organ transplants? How successful are they?

It is organ specific: It depends on the organs....very significant improvements in all fields....rejection rates are better.....organ matchings are better and therefore the ultimate outcomes.....pre and postoperative managements with immunosuppressive drugs are better....yet the challenges remained....because we do not have any specific drugs yet..... ...Read more

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What types of medications should I expect to have to take post-transplant?

Several: Three group of medicines are required. First immunosuppressants to prevent your body rejecting the kidneys, second group for three to six months to prevent some rare infections as a result of the first group and thirdly long term medicines that the patient requires for high blood pressure or other medical conditions such as diabetes, gout, thyroid deficiency etc. ...Read more

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What is the ratio of failed kidney transplants to total kidney transplants?

What is the ratio of failed kidney transplants to total kidney transplants?

Less than 10%: The question is about survival, which is usually measured as percentage of surviving (not failed) kidneys transplanted after a time period, usually one year. Kidney transplant survival after one year is routinely in the 90% range. It depends on the type of kidney transplant (living donor vs deceased donor) the quality of the donor kidney and the health of the transplant recipient. ...Read more

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If humans evolved from apes, then can transplantation occur with a human and an ape?

Yes, but won't last : Transplant between different species, or xenotransplantation can be done, but the organ will be rejected in a short time, as in days to weeks. The antigen is in the blood vessel lining, so as blood passes through them, the host will recognize the organ as foreign and mount a response against it. This does not happen with cells transplanted from organs if there is no vascular tissue attached. ...Read more

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Allograft (Definition)

Allograft, when used medically, generally refers to transplants. One takes a tissue (heart, kidney, skin, liver, lung etc) from one person (same species) and transplants that tissue into another person that is genetically different (within that species). ...Read more


Dr. Amy Friedman
1,111 doctors shared insights

Transplantation (Definition)

Transplantation is the process of transplanting organs from a donor to a recipient and includes surgery ...Read more