Doctor insights on:
Melanoma Staging Prognosis
Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more
Curable!: Stage 3 means the tumor is large and/or the cancer has spread to many lymph nodes. It can still be cured with a combination of surgery, chemotherapy and radiation therapy. The risk of cancer returning depends on many factors-- age, # of involved lymph nodes, and whether the cancer has hormone receptors or her2. About 50% of stage 3 breast cancer patients are cured. Have hope! ...Read moreSee 1 more doctor answer
Pancoast tumor: Occurs at the top of the lung and invades out and up to involve muscles, nerves, and thereby causing pain and horner's syndrome. Metastasis usually means going to another organ. If confined to chest and outward extension (?Metastasis), outlook is more optimistic. If it metastasized to brain, lung, liver or distant bones, the outlook is bleak, seek symptom management, there is no cure. ...Read moreSee 1 more doctor answer
Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read moreSee 1 more doctor answer
Depends: Some cancers are curable with today's chemotherapy even if they have spread extensively. Others (for example, the common lung cancers) may someday be curable when they have reached stage iv, but not today. I've just seen reports of possible cures of stage IV colon and stomach cancers; i'm hopeful. ...Read more
Majority will be No: When the cancer has spread to other organ beyond the primary organ-metastatic disease- or stage 4- , majority , it is an incurable disease. In a very selected case, when the metastatic disease is very limited - 1 or 2- only in the liver or only in the lung- and no other disease anywhere else and if surgery can be done to remove completely, attemp to cure the cancer can be done with chemo & surgery. ...Read moreSee 2 more doctor answers
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more
My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive stage 4 cancer.She's on folfox. Life expectancy??
Varies from months/y: The overall survival of stage 4 colon cancer varies from 1 to 3 years. Most patients have at least 2 years if their tumor responds to chemo. If you tumors regresses after chemo, it may even be surgically removable in which case long term survival(even a cure) can be possible. Ask more questions to your treating oncologist. ...Read more
Yes and No: Certain genetic conditions may predispose someone to malignant melanoma. But there are certainly things that can be done to boost one's immune system to fight cancers. And those with irregular moles should be seen at least yearly by their doctor or dermatologist to remove suspicious moles. Therefore, preventing a metastatic process. ...Read moreSee 2 more doctor answers
Tumor,Nodes,Mets: The t, n, m system classifies breast cancers based upon tumor size(t), lymph node status(n), and presence of cancer elsewhere in the body(m). Stage i is limited to small cancers +/- microscopic ln disease. Stage ii describes tumors 2-5cm +/- ln disease. Stage iii is for more advanced tumors (>5cm, skin/chest wall involvement) +/- multiple/distant ln. Stage IV describes metastatic disease. ...Read moreSee 1 more doctor answer
Sometimes: Stage 4 nb in children over 18 months of age is usually treated aggressively with chemotherapy, then surgery. This is followed with consolidation with high-dose chemotherapy and autologous stem cell transplant and then radiation. Finally, the patient receives minimal residual disease therapy with anti-gd2 monoclonal antibody with cytokines and accutane, for 86% 2 year overall survival. ...Read moreSee 1 more doctor answer
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
Are small melanomas <5mm in diameter less likely to be invasive? Do they have better prognosis than melanomas of larger diameter?
Nodular melanoma: Three of the four types of melanoma remain superficial in the epidermis and grow RADIALLY (laterally), often for several years, before entering the VERTICAL GROWTH PHASE where they grow downward and invade the dermis with the potential to metastasize. The fourth type of melanoma is nodular melanoma which STARTS in the vertical growth phase and can metastasize from the outset. ...Read moreSee 1 more doctor answer
1 melanoma 0.7mm + 1 nevoid melanoma 1 4mm + 2 insitu removed last 7 years and will be having two more moles removed soon, what is my prognosis?
Why the next surgery: 2 "moles" to be removed? Did the DR say WHY? Do they have certain features suggesting melanoma? If the lab finds BENIGN lesions, then you are done, nothing to worry about. If there is melanoma, it will be staged. The prognosis depends on the stage. You need to be thoroughly familiar with the features to look for as suggesting biopsy for melanoma. ...Read more
What is the prognosis of Spindle cell melanoma T4 lesion on the scalp?other than the surgery, what other treatments have been successful?
Skin cancer: Melanoma is a cancer that develops in the melanocytes, pigmented cells of the outer layer of skin. While it is related to sun and uv radiation, it is possible to get melanoma in areas that receive minimal sun exposure. Melanoma is generally considered the most dangerous form of skin cancer, more likely to metastasize than the more common basal or squamous cell cancers. ...Read moreSee 2 more doctor answers
A type of skin cance: Melanoma is a type of skin cancer that arises from the pigmented cells (melanocytes) in the skin. In general, it is more malignant than the other two common skin cancer types (basal cell and squamous cell), but early melanoma has a good prognosis. Look online for the abcde for diagnosing melanoma. If you have a suspicious mole - have it checked out by a deramatologist. It could save your life! ...Read moreSee 2 more doctor answers
Learn your ABCD's: Definitive diagnosis is made by biopsy. Melanomas are screened by the abcd's: a-asymmetry; b-irregular borders; c-different colors; d-diameber >6mm (size of pencil eraser). If you notice a mole with these characteristics, get it checked out asap. If you have a skin lesion which is growing, ulcerating, bleeding, or otherwise changing, get it seen as well for evaluation and possible biopsy. ...Read moreSee 5 more doctor answers
Cancer of melanocyte: Melanoma is cancer of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. These cells predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can originate in any part of the body that contains melanocytes. ...Read moreSee 2 more doctor answers
White people in sun: Sun damage can lead to melanoma and people with fair skin sustain more injury from the sun more rapidly than their darker skinned counterparts. Sun protection from a young age is very important. You can read more at www.Melanomafoundation.Org. ...Read moreSee 2 more doctor answers
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