Doctor insights on:
Melanoma Family History
Depends: Many people have a distant relative who had breast cancer late in life and that is not an indication for brca testing. There are certain criteria like very young breast cancer, male breast cancer, triple negative breast cancer before age 60, and others. Visit your family doc or gyn to see if you need a referral to a genetics health professional for testing. ...Read moreSee 2 more doctor answers
Skin is the largest and one of the most complex organs in the body composed of hundreds of different structures. Nearly any of these elements can degenerate into cancer. However the three most common are: basal cell, squamous cell and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use & ...Read more
VERY VERY IMPORTANT: Dear bgonzalez, i feel that family history is at least 50% of a patient's evaluation. I still believe that family genetics is greater than 50%, perhaps 70% of my focus on a patients's potentially preventable disease. If there is breast cancer in the family at an early age-more attention to early diagnostic testing is appropriate. Myriad now has certain tests available. See their website, . ...Read moreSee 1 more doctor answer
Other than immediate family members (mother father brother sister) should any other family member's medical history be taken in consideration as well?
Grandparents too!: When considering close family history, i also want to include grandparents. Although uncles, aunts, cousins may not be as important, include their information if you have it. ...Read more
Rephrase: besides 30 year pack history what are other significant risk factors for screening for lung cancer? Family history? Other cancer? Polyps?
Important: Family history of cancer is very important information. If your family history of colon cancer is significant ( multiple family members with colon cancer especially at younger age) -then you would need to be screen for colon cancer- started approximately 10 years earlier than the age of the youngest person in the family got diagnosed with colon cancer.You also need to see a genetician if history +. ...Read moreSee 1 more doctor answer
If a family member has ovarian cancer, can genetic screening determine if other family members will get the disease?
Yes: Ovarian cancer, especially pre-menopausal ovarian cancer is a rare disease and i recommend family members of such patients atleast have a genetics consultation to talk about testing. Brca-1 and brca-2 mutations put women at a much higher risk of developing ovarian, breast and endometrial cancers. More common in jewish women. Hnpcc (lynch syndrome) also increases the risks of female cancers. ...Read moreSee 1 more doctor answer
Maybe: If in doubt go to a genetics counselor - most cancer centers have one. The consultation is not expensive, but the test itself is. They will ask about your age, the exact numbers of family members affected, their age at diagnosis, whether one or both breasts, their relationship to you (mother, sister, or daughter increase your personal risk), other cancers in the family. Then they can advise you. ...Read moreSee 1 more doctor answer
Earlier colonoscopy: If you have a significant family history of colon cancer, you would start your colonoscopy 10 years earlier than the age of the youngest family members diagnosed with colon cancer. Significant history - if there are multiple family members with colon ca; if a very young age of diagnosis of colon ca in some family members; diagnoses of other, associated cancers in family members. ...Read moreSee 2 more doctor answers
BRCA Mutations: The genetic mutations responsible for the hereditary type of breast cancer are called BRCA mutations. If either parent has this mutation, there's a 50:50 chance that any of their children will inherit this mutation. Even with this mutation, the chance of breast cancer is not 100%; it's closer to 60%(in women). Keep in mind that only 10-15% of all breast cancers in the US are the hereditary type. ...Read moreSee 2 more doctor answers
No certainity: Although autoimmune disease have high genetic transmission rates, I do not know if you can say who will get what until signs/symptoms appear. So the best advice i can give is that you to be aware of the signs and symptoms of conditions which are prevalent in your family and be vigilant and honest in recognizing them and taking action to be evaluated by a medical professional. ...Read more
Family History BC: Hi, medical investigators typically used the gale questionnaire re: breast cancer risk.The questions would be a first degree relative age less than 50 years old who developed breast cancer. A first degree relative with a brca 1 or 2 mutation. Note:both mother and father's side. This model of familial risk for breast cancer is not as reliable as once was thought. Pls seek bc genetic counselor eval. ...Read moreSee 1 more doctor answer
Should somebody with a family history of breast cancer be more adamant about examination early in life?
Even with + fam: Hx, evidence does not support early mammo's, and they add radiation exposure. Adamant or not, the yield is so low that the risk outweighs it. It it were risk free and cheap, and there are ultrasound devices in development that might do this, there might be a case. ...Read moreSee 1 more doctor answer
23F. Strong family history of colon cancer. Syncope, h/h 7.4/27.7. Fe studies showed anemia, hematologist referred to GI. Chances of cancer?
Low: What is the earliest age which you family members had colon cancer? If you are ten or more years younger than the lowest age of the cancer patient, your risk is very low. Your anemia is more likely due to blood loss in menstrual bleeding. You are doing the right thing by seeking care. Follow your doctors' instructions. ...Read more
See below: If you have a first degree relative (mother or sister) who was diagnosed at age <50 then take the age at diagnosis and subtract 10 years. So if your mother was diagnosed at age 46, you would start at age 36. Otherwise, all women should start annual screening mammograms at age 40. ...Read moreSee 1 more doctor answer
At 30 unlikely but: Age is no exception for cancer , breast cancer was described as young as 6 yr old but very very rare. Woman BRACA genetic mutations breast cancers can occur at early age. Regardless what age any breast lump should bring to the attention of a professional See your doctor ...Read more
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