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Doctor insights on: Melanoma And Enbrel

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Is it safe for a pt with history of basal cell carcinoma and squamous cell carcinoma (father died of malignant melanoma and sister has had a melanoma removed) to take enbrel (etanercept) for ra? Red hair, blue eyes.

Is it safe for a pt with history of basal cell carcinoma and squamous cell carcinoma (father died of malignant melanoma and sister has had a melanoma removed) to take enbrel (etanercept) for ra? Red hair, blue eyes.

Immunosuppressant: Enbrel (etanercept) is an immunosupressant to minimize yuur bodies attack of itself. Anything that lowers your immune system may increase your risk for certain cancers such as lymphoma, basal and squamous cell cancers, particularly if you are already fair skinned. Good sun block, wide brimmed hats, minimize sun exposure, etc. Your doctor should be able to discuss the relative risks of treatment of enbrel (etanercept). ...Read more

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Dr. Mike Bowman
905 doctors shared insights

Skin Cancer (Definition)

Skin is the largest and one of the most complex organs in the body composed of hundreds of different structures. Nearly any of these elements can degenerate into cancer. However the three most common are: basal cell, squamous cell and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use & ...Read more


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How many documented melanoma deaths with patients on enbrel (etanercept)?

How many documented melanoma deaths with patients on enbrel (etanercept)?

Not knowable: I appreciate your concern, but this is the kind of data that can't be obtained by any means. Enbrel (etanercept) is an immunomodulator that may suppress the immune response which has a small impact on melanoma progress; it's also given for psoriasis in which the skin cancer risk is already up. It's worth the risk; do keep a close eye on your skin so that skin cancers get rx'd early & there' s no risk of death. ...Read more

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What are the effects of the shot enbrel (etanercept)?

What are the effects of the shot enbrel (etanercept)?

Well tolerated excep: Despite the fda requiring the package insert to warn one of the development of cancer with the drug, there has been many studies refuting the increased propensity to develop cancer; either lymph, skin or other "solid tumors." the one big risk is infectious complications. The drug does not cause infections; but, it makes it difficult to fight off tuberculosis, fungal infections and viruses. ...Read more

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What is a melanoma?

A type of skin cance: Melanoma is a type of skin cancer that arises from the pigmented cells (melanocytes) in the skin. In general, it is more malignant than the other two common skin cancer types (basal cell and squamous cell), but early melanoma has a good prognosis. Look online for the abcde for diagnosing melanoma. If you have a suspicious mole - have it checked out by a deramatologist. It could save your life! ...Read more

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How is melanoma diagnosed?

How is melanoma diagnosed?

Learn your ABCD's: Definitive diagnosis is made by biopsy. Melanomas are screened by the abcd's: a-asymmetry; b-irregular borders; c-different colors; d-diameber >6mm (size of pencil eraser). If you notice a mole with these characteristics, get it checked out asap. If you have a skin lesion which is growing, ulcerating, bleeding, or otherwise changing, get it seen as well for evaluation and possible biopsy. ...Read more

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What exactly is a melanoma?

Cancer of melanocyte: Melanoma is cancer of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. These cells predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can originate in any part of the body that contains melanocytes. ...Read more

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Is melanoma hereditary? How?

Is melanoma hereditary? How?

IN A SENSE: A positive family history of melanoma is a risk factor. So is hair-blonde or red-color and eye-blue or green-color, which of course you inherit. The biggest risk factor, though, is sun exposure. ...Read more

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How often is melanoma 1-2 mm?

Quite common: Most melanomas in the US are diagnosed when they have thickness of 1mm to 3mm) are diagnosed in about 30% of patients and carry an intermediate prognosis with a risk of recurrence between 15-30%. ...Read more

Dr. Travis Kidner
2,579 doctors shared insights

Melanoma (Definition)

Melanoma is a cancer of the melanocyte cells. Melanocyte cells determine the color of your skin. Although these cells are primarily found in your skin, they can also be found in the bowel ...Read more


Dr. Robert Lowe
121 doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more