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Doctor insights on: Megestrol Side Effects

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Has anyone experienced side effects or symptoms with megace (megestrol)?

Has anyone experienced side effects or symptoms with megace (megestrol)?

Yes, it is possible: This is a very strong progestin medication and is often associated with weight gain, fluid retention, possible blood clots and high blood sugars. Other side effects are possible but less common. ...Read more

Dr. George Canellos
57 doctors shared insights

Megestrol (Definition)

Megestrol is a progestin-based agent which is a kind of women's ...Read more


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Can you tell me about side effects or symptoms with megace or megestrol acetate ?

Can you tell me about side effects or symptoms with megace or megestrol acetate ?

Many side effects.: Body as a Whole: abdominal pain, chest pain, infection, thrush and sarcoma Cardiovascular System: cardiomyopathy and palpitation Digestive System: constipation, dry mouth, hepatomegaly, increased salivation and oral thrush Blood: leukopenia Metabolic and Nutritional: LDH increased, edema and peripheral edema Nervous System: paresthesia, confusion, convulsion, depression More. Many side effects ...Read more

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At age 35... How effective is megestrol acetate in treating endometrial hyperplasia...What are problem side effects....What about ability to conceive?

At age 35... How effective is megestrol acetate in treating endometrial hyperplasia...What are problem side effects....What about ability to conceive?

Good after treatment: Remember you're being treated for a pre-cancerous lining of the uterus. Simple hyperplasia is treated with megestrol to prevent proliferation (growth) to a more aggressive type which may require hysterectomy. If all works well, your gyn can clear you for pregnancy. Side effects are hot flashes, GI symptoms, slight edema but all reversible. Please check with your doc for more details. Stay safe. ...Read more

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After taking megestrol i bled daily for wks. Is this a normal side effect?

After taking megestrol i bled daily for wks. Is this a normal side effect?

Progestin: Breakthrough bleeding can be a side effect of Progesterone based medications such as megestrol (progestin) & will subside after cessation of therapy. If the bleeding is protracted your doctor may prescribe another medication to help stop the bleeding. Consult your doctor or gynecologist to make sure the bleeding was not caused by an underlying gynecological pathology. ...Read more

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I took megace (megestrol) es for about 3 months. People tell me that i look darker, as if I have a tan. Is this a side effect? Will i continue to get darker?

I took megace (megestrol) es for about 3 months. People tell me that i look darker, as if I have a tan. Is this a side effect?  Will i continue to get darker?

Adrenal suppression: One of the possible side effects from Megace (megestrol) is adrenal suppression, which can result in darker pigmentation of the skin. You should contact your physician immediately to notify him/her of this symptom. Depending on why you are taking it and the severity of your other problems, you need to discuss discontinuation of the medication. ...Read more

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Is the drug megestrol acet safe?

Is the drug megestrol acet safe?

Depends: Thsi drug sis used for a number of conditionc including cachexia ( appetite) or breast cancer . It is usually benign but can have some side effects. ...Read more

Dr. Zahid Niazi
41 doctors shared insights

Megace (Definition)

Megace is a progestin-based agent which is a kind of women's ...Read more