Doctor insights on:
Medicine For Waldenstrom Macroglobulinemia
It is type of cancer: This condition affects your blood cells and lymph nodes. It is related to another blood cancer, called multiple myeloma.There is good treatment available for it. You will be best served by seeing a hematologist (Blood specialist) who can diagnose and treat you better. ...Read more
Paraprotein: Waldenstrom's looks like a low-grade lymphoma rather unusual plasma cells, and produces IgM pentamer molecules instead of IgG or IgA monomers or free light chains. It tends to occupy lymph nodes rather than marrow. Hyperviscosity of the blood is likely to be the most troublesome feature. ...Read more
Would normal CBC, metabolic panel, ESR, CRP, PT, aPTT, d-dimer make multiple myeloma or waldenstrom macroglobulinemia unlikely? Given a presumptive diagnosis of von Willebrand at age 31 with no known family history. Concerned it may be acquired form.
Not right tests: If you wish to be tested for multiple myeloma or Waldenstrom, you should have serum protein electrophoresis and immunofixation electrophoresis and if needed similar studies on urine. It is not a do it yourself diagnosis and your doctor should order the tests, if warranted. ...Read more
See below: Could you please ask in english.Get a more detailed answer ›
Perhaps: People with waldenstrom's macroglobulinemia usually go to their doctor because of lymph node enlargement. This is usually not painful. Because of the protein the lymphoma cells make, one might have a headache, shortness of breath or other symptoms. As the disease progresses, symptoms can worsen. In late stages, anemia and other low blood counts become more problematic. ...Read more
Plasmapheresis: If you have a large amount of IgM in your bloodstream and it is causing problems, for example with your nervous system, and you are offered plasmapheresis, then by all means accept it. If you are offered Rituximab or a autologous marrow transplant, get all the facts but consider these options especially if your disease progresses. ...Read more
Seek help from. ....: There are many options- contact yor local chapter of the leukemia & lymphoma society or the american cancer society to get information on local oncologists at free clinics in your area. Some hospitals with cancer programs can get you in help you obtain emergency medical assistance especially if you need treatment such as state medicaid. ...Read more
What are some good concrete metrics in defining remission for waldenstrom's macroglobulinemia - in terms of bone marrow analysis and IgM level?
50%, 90%, 100%:
Conﬁrmation of response in wm has been
adopted from response criteria for multiple
myeloma. See http://www. Iwmf. Com/docs/ghobrial_clincial_trials. Pdf
especially see tables xi, xii. The treatment of wm is aimed at control of symptomatic disease. Risk/benefits of various therapies are highly individualized based on patient and disease characteristics. ...Read more
Is a tiny IgM kappa monoclonal protein migrating in beta2 region considered specific for waldenström's macroglobulinemia irrespective of size?
No. MGUS: Mgus = monoclonal gammopathy of unknown significance. Igm is associated more with waldenstrom's macroglobulinemia (vs igg, iga, igd, ige with multiple myeloma). More info on background is here: http://bloodjournal. Hematologylibrary. Org/content/109/12/5096.Full" rel="nofollow" ta. ...Read more
IgM is macroglobulin: Macroglobulinemia is the term for monoclonal igm. However what you described is confusing/erroneous term, igm kappa is not light chain gammopathy. Igm kappa, by definition is macroglobulin. ...Read more
Low grade lymphoma: It is a disorder where one produces more antibody, specifically igm. This antibody is large so when in increased numbers can lead to several problems. These include what is called hyper viscosity syndrome. As there is too much of this protein, it tends to clog small arterioles and can lead to such things as mouth sores, kidney problems and other issues. The goal is keep the level down. ...Read more
For what purpose?: Libido? Erectile function? Premature ejaculation? "sex enhancing" seems to me to be a very broad topic. Best to chat w/your family doc to figure out what's wrong. Then consider appropriate treatment. Check out http://alvinblin. Blogspot. Com/search/label/libido, http://alvinblin. Blogspot. Com/search/label/erectile%20dysfunction & http://alvinblin. Blogspot. Com/search/label/premature%20ejaculation. ...Read more
Antihistamines: A cold is a viral infection, usually resolves on its own. People take medicines to resolve symptoms. Cough medicine like Guaifenesin and antihistamines like cetirizine, fexofenadine, loratidine, are commonly used for drainage, warm salt water rinses may help with the sore throat. If it doesn't improve seek a doctor. ...Read more
Not a standard: Abbreviation. I really have no idea. Can you put it in context? Where did you see it? If I'm making up things...obstructive tonsillar hypertrophy? Of the heart? Odd tooth brushing habits? Short for Other? ...Read more
Yes, I do: It depends on the patient, the problem, and the skill of the homeopath in taking the case, though. Some problems are not appropriate to treat primarily with homeopathy, and doing this will be both ineffective and possibly unsafe. I've personally worked with many patients not helped through conventional means, and witnessed their gradual recovery. I've had positive results in my own health too. ...Read more
Definition: The dsm-iv-tr has very specific criteria for substance abuse or substance dependence. Substance misuse, however, is not well defined but often the term is used when a person is engaging in maladaptive behaviors with regard to a substance that does not meet full criteria for abuse or dependence. Getting help before the problem worsens is key. Aa/na and sponsor and getting treatment for the problem. ...Read more
Psychologic effect: By acid, I assume you mean LSD. LSD can produce psychological effects and altered sense of reality. Remember the Beatles song Lucy in the Sky With Diamonds? The song is reportedly describes the effects of LSD. While it is not physically additive, using LSD on a regular basis, the hallucinogenic effect of drug can make it difficult for the user to have any normal sense of reality. So avoid use. ...Read more
The one that works: I have a preference for vyvanse (lisdexamfetamine). It has a smooth curve and can taken once a day. I do prescribe all of them, and unfortunately it often boils down to the availability of the medications (shortages have occurred) and which meds the insurance co will cover. ...Read more
Yes most of the time: It depends but after life style modification like loosing weight, salt restriction. Dash diet, exercisising regularly do not help control elevated blood pressure.Once drugs are started and tolerated they need to be taken all your life in most cases. Of course there are rarely exception as life style modification may be successful and drugs may be reduced in dosage or stopped under medical supervision. ...Read more
Medicine isn't alway: Needed. Cold tips: for sore throat – gargle with warm salt water (1/2 tsp salt in 8 oz of water). * for congestion – saline nose drops or a netti pot. *for anti-inflammatory effect ; mobilizing mucus- homemade chicken noodle soup.**for hydration- lots of water. Try clear broth. * add honey ; a small amt. Of lemon juice to chamomile tea. ...Read more
No: Prescriptions can not be written. This is a patient education forum. It seems that you have some important conditions that need an expert physician talk to you face to face and then recommend most appropriate treatment. ...Read more
Usually: Most medications do not cross react. Your prescribing doctor should know all you are taking to avoid giving you a problematic medication. The pharmacist commonly will detect such problems. Mostly they are uncommon. ...Read more
1. Throat coat liquorice tea: several times/day
2. Megafood Megaflora plus probiotics 4 caps 2 times/day for 1 week.
3. Sunshine for 30-45 minutes daily at noon or Vitamin D3 10, 000 IU/day (NOW brand is good)
4. Zinc supplement 50 mg/day (NOW brand is good) with food for 7-10 days
5. No milk products for 10-15 days ...Read more
Serious problem: There are many entry points into the drug distribution channels and the fda cannot be everywhere. Many drugs are so expensive that unethical manufacturers have produced ineffective imitations that can be either dangerous or have no drug in them. We have to trust our pharmacists and the good work of regulators but there is a risk. The actual percentage is only a guess. ...Read more
There are a few causes of headache. One of them is called a migraine. True migraines are severe, often on one side of the head, and often associated with nausea and vomiting. People with headaches often get relieve with aspirin, tylenol, (acetaminophen) ibuprofen, and similar drugs that are called non-steroidal antiiflammatory agents.
There are specific treatments for migraine, that require a prescription. ...Read more