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Doctor insights on: Medicine For Thrombotic Thrombocytopenia Purpura

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Can you die from thrombotic thrombocytopenia purpura?

Can you die from thrombotic thrombocytopenia purpura?

YES: Unfortunately, yes.
People can die from ttp. They can develop seizure, coma, renal failure, cardiac hemmorhage/bleeding, sudden cardiac arrest, myocardial infarction etc.
Need to get treatment as soon as possible. ...Read more

Non Blanching Red Or Purple Spots (Definition)

Non blanching red or purple spots can describe purpura, which is bleeding beneath the skin that does not blanch with pressure. It can be caused by platelet disorders, coagulation disordes, vascular ...Read more


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What is the disease? Thrombotic thrombocytopenia purpura?

What is the disease? Thrombotic thrombocytopenia purpura?

Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma. ...Read more

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Most common symptoms of thrombotic thrombocytopenia purpura?

Most common symptoms of thrombotic thrombocytopenia purpura?

Range of symptoms: Ttp can involve many different organs. One can have renal dysfunction, fever, altered mental status, low platelet counts and hemolytic anemia. These signs can lead to symptoms of bleeding, bruising, petechiae, confusion, anemia, fatigue, and possible jaundice among other things. ...Read more

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How common is it for somebody to get thrombotic thrombocytopenia purpura?

How common is it for somebody to get thrombotic thrombocytopenia purpura?

Rare disease: This is a rare but life-threatening disease; approx 2-3 cases per 100, 000 population in the USA are seen. ...Read more

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What is the definition or description of: thrombotic thrombocytopenia purpura?

What is the definition or description of: thrombotic thrombocytopenia purpura?

TTP is a serious: Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke.

This is an absolute medical emergency. ...Read more

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How come I have thrombotic thrombocytopenia purpura, but nobody else in the family has it?

Not hereditary: Ttp of thrombotic thrombocytopenic purpura is not a hereditary disease. Most of them is idiopathic i.e. Unknown etiology in about 37 percent. Others are related to drugs, autoimmune disease, infection such as hiv, endothelial injury, stem cell transplant etc. ...Read more

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Do people with thrombotic thrombocytopenia purpura have a lot of pain?

No usually: People with itp usually bleed more frequently following gently trauma, like a bump. In more severe forms, itp can be associated with gastric hemmorrages, which are painful, but this is rare. ...Read more

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Difference between idiopathic thrombocytopenia purpura and thrombotic thrombocytopenia purpura?

The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange. ...Read more

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What is the treatment for thrombotic thrombocytopenia purpura?

Plasma transfusion: Ttp is due to deficiency of an enzyme normally present in blood. This enzyme controls the activation of platelets. The deficient enzyme is usually replaced by transfusing plasma and in severe cases by exchanging the patient's plasma with normal plasma. ...Read more

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What is idiopathic thrombocytopenia purpura?

Autoimmune disease: Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few platelets in the blood. Check this site:
http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0001562/. ...Read more

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What is the treatment for idiopathic thrombocytopenia purpura?

What is the treatment for idiopathic thrombocytopenia purpura?

Steroids & surgery: Many cases of itp resolve with supportive care and corticosteroid treatment. In resistant cases, spleen, the site of platelet destruction, may be removed. ...Read more

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Is thrombocytopenia purpura as the same as blood dyscrasia?

Is thrombocytopenia purpura as the same as blood dyscrasia?

Different: Thrombocytopenic purpura (ttp) is an acute condition involving destruction of blood components including red cells and platelets and can be life threatening. Blood dyscrasia is a general term referring to a chronic or inherited blood compnent disorder such as hemophilia, leukemia, thalassemia, etc. ...Read more

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In the case of idiopathic thrombocytopenia purpura is pregnancy dangerous?

High risk pregnancy: It is something that is manageable, however. You should see a perinatologist for your high risk pregnancy to make sure your baby is okay and also see a hematologist through out your pregnancy- to make sure you and baby are okay. Your hematologist will be able to help and give you the necessary treatment as indicated- like-platelet transfusion, ivig, steroid etc. ...Read more

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Is it possible that I can get idiopathic thrombocytopenia pupura a second time?

Chronic disorder: Itp in adults is often a chronic disorder. There may be a period of remission which makes it appear that a person is getting the disease second time, when it in fact it was never cured. ...Read more

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What is thrombotic thrombocytopenic purpura (ttp)?

Platelet disorder.: Ttp is a blood disorder in which platelets form small clots. Formation of these clots uses up so many platelets that platelet count becomes low. The clots can get stuck in small blood vessels and cause damage to red blood cells, causing anemia. Other symptoms of ttp include fever, kidney failure, & neurologic problems. The biological cause of ttp is still uncertain. ...Read more

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Could someone tell me how many different kinds of Thrombotic thrombocytopenic purpura there is cause I had ttp and I thought there was just 1 kind?

Subtypes: You may have been born with low or poorly functioning ADAMTS13 (Upshaw's), or make an antibody to it, or otherwise have it inhibited, or get a TTP-like illness without a detectable inhibitor or mutation. It's good you're learning about your illness, and it's fortunate your physicians made the call. ...Read more

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What type of physician is best suited to treat thrombotic thrombocytopenic purpura?

What type of physician is best suited to treat thrombotic thrombocytopenic purpura?

TTP is managed by: A hematologist. Assistance may be needed from lab medicine or nephrology for plasma exchange therapy. Immunology, neurology and other consultants may be called in to help. ...Read more

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I have thrombotic thrombocytopetic purpura and I want to know if its safe to take birth control pills?

I have thrombotic thrombocytopetic purpura and I want to know if its safe to take birth control pills?

Avoid estrogen: Since ttp can sometimes be triggered by estrogen, you should probably avoid combination pills. The 'mini-pill' that has no estrogen might be an option. Talk with your gyn to come up with a safe, effective contraceptive plan. ...Read more

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What tests would you order on a patient presenting with possible drug induced thrombocytopenia (minor petechiae after taking an antihistamine) and why?

What tests would you order on a patient presenting with possible drug induced thrombocytopenia (minor petechiae after taking an antihistamine) and why?

Recheck platelet cou: Serial platelet counts is all we check till the counts recover. Tell us the actual platelet count...then we can advise you better. If the platelet count is more than
100, 000, then we stop to worry about it. ...Read more

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Does TGF Beta Biomarker helps with diagnosis of what trigger cyclic thrombocytopenia in adult men with no drug and medication use?

Does TGF Beta Biomarker helps with diagnosis of what trigger cyclic thrombocytopenia in adult men with no drug and medication use?

TGF etc..: Hello ~ prob'ly not. Very brief review of the literature done and I could not find this connection. Its not an appropriate use of my time here to do in depth review of the literature to find arcane connections of biomarkers to rare diseases. This is a complex issue + I am sure you are well acquainted with using Internet search engines or Pubmed. Relevant personal info you should d/w treating Oncol ...Read more

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Male 31 with Cyclic Thrombocytopenia, no drug or medicine or infection. What causes Cyclic thrombocytopenia, it can get as a low as 16 and move back up?

Male 31 with Cyclic Thrombocytopenia, no drug or medicine or infection. What causes Cyclic thrombocytopenia, it can get as a low as 16 and move back up?

You need med monitin: You may have a condition called Immune thrombocytopenic purpura (ITP). I assume, that you are under the medical supervision of a hematologist or oncologist. We need to know for how long have you known about your low/fluctuating platelet counts?
There are many options of treatment for ITP. This is something your doctor can explain to you. As long as your platelet count remains>50, 000, yr safe. ...Read more

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How long does thrombocytopenia last?

How long does thrombocytopenia last?

Depends: Thrombocytopenia means low platelet count. It is an abnormal lab- like a symptom, not a disease. There are many reasons for it and "how long it lasts" depends on the cause. It can be from toxic exposure (examples= radiation, alcohol, or drugs), an immune problem ("ITP"), from infections or from bone marrow dysfunction. It can be from Leukemia or from treatment of Leukemia. NEED MORE INFORMATION. ...Read more

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Thrombocytopenia, how long does it last?

Thrombocytopenia, how long does it last?

It depends on cause: You need to know the cause. One common cause is called idiopathic thrombocytopenic purpura or itp. This is a chronic condition which can last from a few months to several years. Other causes can be short lived and platelets recover. You should be sure to find out the cause. Or seek a second opinion to learn more about your problem from another specialist. ...Read more

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Can anyone help me to explain what is thrombocytopenia?

Low platelets: It literally means a low number of platelets - lower than the "average, healthy" person. There are many reasons for that - sometimes if it is minor, it is of no consequence. See your doctor to discuss it. ...Read more

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What can you tell me about thrombocytopenia? Is there a cure?

Thrombocytopenia: platelet count is the balance between production (by the Bone Marrow) and consumption. Depending on the cause of Thrombocytopenia you can determine if it is curable or not. If the cause is reversible, YES it is curable. Causes such as low B12/Folate, or some types of hypothyroidism are reversible and correcting these causes may lead to cure. ...Read more

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What causes hypoproliferative thrombocytopenia? What are the best diagnosis tests to determine hypoproliferative thrombocytopenia?

What's the cause?: This can be due to anything from drinking quinine bitters to having leukemia or cancer in the marrow to any of a variety of other things. It is not an illness on itself. ...Read more

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What is thrombocytopenia and how is a prothrombin time test used?

What is thrombocytopenia and how is a prothrombin time test used?

Blood clotting: Thrombocytopenia means low level of blood plateletes. Prothrombin time is a test for extrinsic coagulation pathway that is initiated with factor vii. Vitamin k deficiency or use of Coumadin (warfarin) or liver function deficiency will prolong the prothrombin time, while several blood clotting diseases that affect intrinsic coagulation such as von willibrand or hemophila will not affect prothrombin time. ...Read more

Purpura (Definition)

Purpura are non blanching red or purple spots caused by bleeding beneath the skin. The spots do not blanch with pressure. They can be caused by platelet disorders, coagulation disordes, vascular ...Read more


Dr. Liawaty Ho
1,058 Doctors shared insights

Thrombocytopenia (Definition)

Deficiency of platelets in the blood. This causes bleeding into the tissues, bruising, and slow ...Read more