Doctor insights on:
Medicine For Thrombotic Thrombocytopenia Purpura
Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma. ...Read more
Range of symptoms: Ttp can involve many different organs. One can have renal dysfunction, fever, altered mental status, low platelet counts and hemolytic anemia. These signs can lead to symptoms of bleeding, bruising, petechiae, confusion, anemia, fatigue, and possible jaundice among other things. ...Read more
Rare disease: This is a rare but life-threatening disease; approx 2-3 cases per 100, 000 population in the USA are seen. ...Read more
TTP is a serious:
Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke.
This is an absolute medical emergency. ...Read more
The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange. ...Read more
Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few platelets in the blood. Check this site:
http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0001562/. ...Read more
Different: Thrombocytopenic purpura (ttp) is an acute condition involving destruction of blood components including red cells and platelets and can be life threatening. Blood dyscrasia is a general term referring to a chronic or inherited blood compnent disorder such as hemophilia, leukemia, thalassemia, etc. ...Read more
High risk pregnancy: It is something that is manageable, however. You should see a perinatologist for your high risk pregnancy to make sure your baby is okay and also see a hematologist through out your pregnancy- to make sure you and baby are okay. Your hematologist will be able to help and give you the necessary treatment as indicated- like-platelet transfusion, ivig, steroid etc. ...Read more
Platelet disorder.: Ttp is a blood disorder in which platelets form small clots. Formation of these clots uses up so many platelets that platelet count becomes low. The clots can get stuck in small blood vessels and cause damage to red blood cells, causing anemia. Other symptoms of ttp include fever, kidney failure, & neurologic problems. The biological cause of ttp is still uncertain. ...Read more
I had taken mornibg after pill twice this year should I be scared? And I have thrombotic thrombocytopetic purpura.
Repeat question: Should you be scared? Of what? Is your ttp in remission? ...Read more
Could someone tell me how many different kinds of Thrombotic thrombocytopenic purpura there is cause I had ttp and I thought there was just 1 kind?
Subtypes: You may have been born with low or poorly functioning ADAMTS13 (Upshaw's), or make an antibody to it, or otherwise have it inhibited, or get a TTP-like illness without a detectable inhibitor or mutation. It's good you're learning about your illness, and it's fortunate your physicians made the call. ...Read more
I have thrombotic thrombocytopetic purpura and I want to know if its safe to take birth control pills?
What tests would you order on a patient presenting with possible drug induced thrombocytopenia (minor petechiae after taking an antihistamine) and why?
Does TGF Beta Biomarker helps with diagnosis of what trigger cyclic thrombocytopenia in adult men with no drug and medication use?
TGF etc..: Hello ~ prob'ly not. Very brief review of the literature done and I could not find this connection. Its not an appropriate use of my time here to do in depth review of the literature to find arcane connections of biomarkers to rare diseases. This is a complex issue + I am sure you are well acquainted with using Internet search engines or Pubmed. Relevant personal info you should d/w treating Oncol ...Read more
Male 31 with Cyclic Thrombocytopenia, no drug or medicine or infection. What causes Cyclic thrombocytopenia, it can get as a low as 16 and move back up?
You need med monitin:
You may have a condition called Immune thrombocytopenic purpura (ITP). I assume, that you are under the medical supervision of a hematologist or oncologist. We need to know for how long have you known about your low/fluctuating platelet counts?
There are many options of treatment for ITP. This is something your doctor can explain to you. As long as your platelet count remains>50, 000, yr safe. ...Read more
I'm an 18 year old male with severe thrombocytopenia and anemia discovered on a cbc. Bone marrow biopsy was normal. Cat was normal. No viruses. No offending drugs. No lupus. Any ideas of a diagnosis?
Depends: Thrombocytopenia means low platelet count. It is an abnormal lab- like a symptom, not a disease. There are many reasons for it and "how long it lasts" depends on the cause. It can be from toxic exposure (examples= radiation, alcohol, or drugs), an immune problem ("ITP"), from infections or from bone marrow dysfunction. It can be from Leukemia or from treatment of Leukemia. NEED MORE INFORMATION. ...Read more
It depends on cause: You need to know the cause. One common cause is called idiopathic thrombocytopenic purpura or itp. This is a chronic condition which can last from a few months to several years. Other causes can be short lived and platelets recover. You should be sure to find out the cause. Or seek a second opinion to learn more about your problem from another specialist. ...Read more
Thrombocytopenia: platelet count is the balance between production (by the Bone Marrow) and consumption. Depending on the cause of Thrombocytopenia you can determine if it is curable or not. If the cause is reversible, YES it is curable. Causes such as low B12/Folate, or some types of hypothyroidism are reversible and correcting these causes may lead to cure. ...Read more
What causes hypoproliferative thrombocytopenia? What are the best diagnosis tests to determine hypoproliferative thrombocytopenia?
Blood clotting: Thrombocytopenia means low level of blood plateletes. Prothrombin time is a test for extrinsic coagulation pathway that is initiated with factor vii. Vitamin k deficiency or use of Coumadin (warfarin) or liver function deficiency will prolong the prothrombin time, while several blood clotting diseases that affect intrinsic coagulation such as von willibrand or hemophila will not affect prothrombin time. ...Read more